Wendy Cheng

TL;DR: Antibody to Campylobacter pyloridis was measured by ELISA in the sera of 160 patients from whom gastric biopsy specimens were also obtained, and Histological diagnosis of active chronic gastritis was associated with a high median ELISA titer (485 E), chronic gast arthritis with a much lower titer(150 EU), and normal histology with a titer of 110 EU.

TL;DR: Oral GS-9620 was safe, well tolerated, and associated with induction of peripheral ISG15 production in the absence of significant systemic IFN-alpha levels or related symptoms in patients with chronic hepatitis B.

TL;DR: Tenofovir alafenamide 25 mg was safe and well tolerated; declines in HBV DNA were similar to ten ofovir disoproxil fumarate at all doses evaluated.

TL;DR: It is demonstrated that a single-nucleotide polymorphism (rs12979860) in the intronic region of interferon-λ4 (IFNL4) is a strong predictor of fibrosis in an aetiology-independent manner and is maximal in young females, especially those with HCV genotype 3.

TL;DR: Drug and host immune responses are likely to provide powerful selection forces that shape HCV genetic diversity and replication dynamics, and considered in terms of drug resistance as well as host “immune resistance” in the STAT‐C treatment era could provide important information toward an optimized and individualized therapy for chronic hepatitis C.