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William J. Horton
Researcher at Bucknell University
Publications - 20
Citations - 1397
William J. Horton is an academic researcher from Bucknell University. The author has contributed to research in topics: Nicotine & Opioid. The author has an hindex of 10, co-authored 18 publications receiving 1213 citations. Previous affiliations of William J. Horton include Michigan State University & Pennsylvania State University.
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Journal ArticleDOI
Variants in nicotinic receptors and risk for nicotine dependence
Laura J. Bierut,Jerry A. Stitzel,Jen C. Wang,Anthony L. Hinrichs,Richard A. Grucza,Xiaoling Xuei,Nancy L. Saccone,Scott F. Saccone,Sarah Bertelsen,Louis Fox,William J. Horton,Naomi Breslau,John P. Budde,C. Robert Cloninger,Danielle M. Dick,Tatiana Foroud,Dorothy K. Hatsukami,Victor Hesselbrock,Eric O. Johnson,John Kramer,Samuel Kuperman,Pamela A. F. Madden,Kevin Mayo,John I. Nurnberger,Ovide F. Pomerleau,Bernice Porjesz,Oliver Reyes,Marc A. Schuckit,Gary E. Swan,Jay A. Tischfield,Howard J. Edenberg,John P. Rice,Alison Goate +32 more
TL;DR: This study confirms that at least two independent variants in this nicotinic receptor gene cluster contribute to the development of habitual smoking in some populations, and it underscores the importance of multiple genetic variants contributing to theDevelopment of common diseases in various populations.
Journal ArticleDOI
Human Connectome Project informatics: quality control, database services, and data visualization.
Daniel S. Marcus,Michael P. Harms,Abraham Z. Snyder,Mark Jenkinson,J. Anthony Wilson,Matthew F. Glasser,M Deanna,Kevin A. Archie,Gregory C. Burgess,Mohana Ramaratnam,Michael R. Hodge,William J. Horton,Rick Herrick,Timothy R. Olsen,Michael McKay,Matthew House,Michael Hileman,Erin Reid,John W. Harwell,Timothy S. Coalson,Jon Schindler,Jennifer Stine Elam,Sandra W. Curtiss,David C. Van Essen +23 more
TL;DR: The Human Connectome Project has developed protocols, standard operating and quality control procedures, and a suite of informatics tools to enable high throughput data collection, data sharing, automated data processing and analysis, and data mining and visualization.
Journal ArticleDOI
The Incentive Salience of Alcohol: Translating the Effects of Genetic Variant in CNR1
Kent E. Hutchison,Heather M. Haughey,Michelle Niculescu,Joseph P. Schacht,Alan Kaiser,Jerry A. Stitzel,William J. Horton,Francesca M. Filbey +7 more
TL;DR: Individuals with the C allele may be more susceptible to changes in the mesocorticolimbic neurocircuitry that is involved in the attribution of incentive salience after repeated exposure to alcohol.
Journal ArticleDOI
ConnectomeDB--Sharing human brain connectivity data
Michael R. Hodge,William J. Horton,Timothy T. Brown,Rick Herrick,Timothy R. Olsen,Michael Hileman,Michael McKay,Kevin A. Archie,Eileen A. Cler,Michael P. Harms,Gregory C. Burgess,Matthew F. Glasser,Jennifer Stine Elam,Sandra W. Curtiss,M Deanna,Robert Oostenveld,Linda J. Larson-Prior,Kamil Ugurbil,David C. Van Essen,Daniel S. Marcus +19 more
TL;DR: ConnectomeDB is a database for housing and disseminating data about human brain structure, function, and connectivity, along with associated behavioral and demographic data, and is geared towards public distribution.
Journal ArticleDOI
Delayed behavioural aging and altered mortality in Drosophila beta integrin mutants.
M. M. Goddeeris,E. Cook-Wiens,William J. Horton,H. Wolf,Jon R. Stoltzfus,M. Borrusch,M. S. Grotewiel +6 more
TL;DR: It is reported here that age‐related declines in locomotor activity are ameliorated and that mean lifespan is increased in myospheroid mutants, and data indicate that functional senescence and age‐dependent mortality are influenced by β integrins in Drosophila.