O
Ovide F. Pomerleau
Researcher at University of Michigan
Publications - 134
Citations - 10743
Ovide F. Pomerleau is an academic researcher from University of Michigan. The author has contributed to research in topics: Nicotine & Abstinence. The author has an hindex of 51, co-authored 134 publications receiving 10413 citations. Previous affiliations of Ovide F. Pomerleau include University of Connecticut & Columbia University.
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Journal ArticleDOI
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
Scott F. Saccone,Anthony L. Hinrichs,Nancy L. Saccone,Gary A. Chase,Karel Konvicka,Pamela A. F. Madden,Naomi Breslau,Eric O. Johnson,Dorothy K. Hatsukami,Ovide F. Pomerleau,Gary E. Swan,Alison Goate,Joni L. Rutter,Sarah Bertelsen,Louis Fox,Douglas A. Fugman,Nicholas G. Martin,Grant W. Montgomery,Jen C. Wang,Dennis G. Ballinger,John P. Rice,Laura J. Bierut +21 more
TL;DR: This study represents one of the most powerful and extensive studies of nicotine dependence to date and has found novel risk loci that require confirmation by replication studies.
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Reliability of the Fagerstrom Tolerance Questionnaire and the Fagerstrom Test for Nicotine Dependence.
TL;DR: Both the FTQ (in both samples) and the FTND proved to be highly reliable and the validity of the scales, using cotinine, number of years smoked, and the "addictive" factor on the Classification of Smoking by Motives questionnaire as criterion variables, was supported.
Journal ArticleDOI
Novel genes identified in a high-density genome wide association study for nicotine dependence
Laura J. Bierut,Pamela A. F. Madden,Naomi Breslau,Eric O. Johnson,Dorothy K. Hatsukami,Ovide F. Pomerleau,Gary E. Swan,Joni L. Rutter,Sarah Bertelsen,Louis Fox,Douglas A. Fugman,Alison Goate,Anthony L. Hinrichs,Karel Konvicka,Nicholas G. Martin,Grant W. Montgomery,Nancy L. Saccone,Scott F. Saccone,Jen C. Wang,Gary A. Chase,John P. Rice,Dennis G. Ballinger +21 more
TL;DR: This study nominates several novel genes, such as Neurexin 1 (NRXN1), in the development of nicotine dependence while also identifying a known candidate gene, the beta3 nicotinic cholinergic receptor.
Journal ArticleDOI
Variants in nicotinic receptors and risk for nicotine dependence
Laura J. Bierut,Jerry A. Stitzel,Jen C. Wang,Anthony L. Hinrichs,Richard A. Grucza,Xiaoling Xuei,Nancy L. Saccone,Scott F. Saccone,Sarah Bertelsen,Louis Fox,William J. Horton,Naomi Breslau,John P. Budde,C. Robert Cloninger,Danielle M. Dick,Tatiana Foroud,Dorothy K. Hatsukami,Victor Hesselbrock,Eric O. Johnson,John Kramer,Samuel Kuperman,Pamela A. F. Madden,Kevin Mayo,John I. Nurnberger,Ovide F. Pomerleau,Bernice Porjesz,Oliver Reyes,Marc A. Schuckit,Gary E. Swan,Jay A. Tischfield,Howard J. Edenberg,John P. Rice,Alison Goate +32 more
TL;DR: This study confirms that at least two independent variants in this nicotinic receptor gene cluster contribute to the development of habitual smoking in some populations, and it underscores the importance of multiple genetic variants contributing to theDevelopment of common diseases in various populations.
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Neuroregulators and the reinforcement of smoking: Towards a biobehavioral explanation
TL;DR: It is proposed that nicotine is "used" by smokers to produce temporary improvements in performance or affect, and a potential large number of exteroceptive and interoceptive cues unrelated to the nicotine-dependence cycle may serve as discriminative stimuli for smoking, over and above smoking to terminate or avoid withdrawal.