F
Frank Cobelens
Researcher at University of Amsterdam
Publications - 268
Citations - 9186
Frank Cobelens is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Tuberculosis & Population. The author has an hindex of 43, co-authored 243 publications receiving 8155 citations. Previous affiliations of Frank Cobelens include University of London & Radboud University Nijmegen.
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Journal ArticleDOI
Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study
Catharina Boehme,Mark P. Nicol,Mark P. Nicol,Pamela Nabeta,Joy Sarojini Michael,Eduardo Gotuzzo,Rasim Tahirli,Ma Tarcela Gler,Robert Blakemore,William Worodria,Christen Gray,Laurence Huang,Tatiana Cáceres,Rafail Mehdiyev,Lawrence Raymond,Andrew Whitelaw,Andrew Whitelaw,Kalaiselvan Sagadevan,Heather Alexander,Heather Alexander,Heidi Albert,Frank Cobelens,Helen M Cox,David Alland,Mark D. Perkins +24 more
TL;DR: The Xpert MTB/RIF test can effectively be used in low-resource settings to simplify patients' access to early and accurate diagnosis, thereby potentially decreasing morbidity associated with diagnostic delay, dropout and mistreatment.
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LTBI: latent tuberculosis infection or lasting immune responses to M. tuberculosis? A TBNET consensus statement.
Ulrich Mack,Giovanni Battista Migliori,Martina Sester,Hans L. Rieder,Stefan Ehlers,Delia Goletti,Aik Bossink,Klaus Magdorf,Christoph Hölscher,Beate Kampmann,S. M. Arend,A Detjen,Graham H. Bothamley,Jean-Pierre Zellweger,Heather Milburn,Roland Diel,Pernille Ravn,Frank Cobelens,P J Cardona,B Kan,Ivan Solovic,Raquel Duarte,Daniela Maria Cirillo +22 more
TL;DR: The main issue regarding testing is to restrict it to those who are known to be at higher risk of developing tuberculosis and who are willing to accept preventive chemotherapy, and to identify an adaptive immune response against, but not necessarily a latent infection with, M. tuberculosis.
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Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial.
Martin Adjuik,Patrice Agnamey,Abdel Babiker,Steffen Borrmann,Steffen Borrmann,Philippe Brasseur,M. Cisse,Frank Cobelens,Diallo S,Jean-François Faucher,Paul Garner,S. Gikunda,Peter G. Kremsner,Peter G. Kremsner,Sanjeev Krishna,Sanjeev Krishna,Bertrand Lell,Bertrand Lell,M. Loolpapit,Pierre-Blaise Matsiegui,Michel A. Missinou,Michel A. Missinou,J. Mwanza,Francine Ntoumi,Piero Olliaro,P. Osimbo,Philipp Rezbach,Philipp Rezbach,Eliab Some,Walter R. J. Taylor +29 more
TL;DR: The combination of artesunate and amodiaquine improved treatment efficacy in Gabon and Kenya, and was equivalent in Sénégal, and is a potential combination for use in Africa.
Journal ArticleDOI
Rapid diagnosis of tuberculosis with the Xpert MTB/RIF assay in high burden countries: a cost-effectiveness analysis.
Anna Vassall,Sanne van Kampen,Hojoon Sohn,Joy Sarojini Michael,K. R. John,Saskia den Boon,J. Lucian Davis,Andrew Whitelaw,Andrew Whitelaw,Mark P. Nicol,Mark P. Nicol,Maria Tarcela Gler,Anar Khaliqov,Carlos Zamudio,Mark D. Perkins,Catharina Boehme,Frank Cobelens +16 more
TL;DR: A cost-effectiveness study reveals that Xpert MTB/RIF is a cost-effective method of tuberculosis diagnosis that is suitable for use in low- and middle-income settings.
Journal ArticleDOI
Comparison of two interferon-gamma assays and tuberculin skin test for tracing tuberculosis contacts.
Sandra M. Arend,Steven F. T. Thijsen,Eliane M. S. Leyten,John J. M. Bouwman,Willeke P. J. Franken,Ben F. P. J. Koster,Frank Cobelens,Arend-Jan van Houte,Ailko W. J. Bossink +8 more
TL;DR: In this article, the authors compared TST, QFT-GIT and T-SPOT.TB in bacillus Calmette-Guerin unvaccinated contacts and correlate results with measures of recent exposure.