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Xiangyu Zhang
Researcher at Picower Institute for Learning and Memory
Publications - 8
Citations - 813
Xiangyu Zhang is an academic researcher from Picower Institute for Learning and Memory. The author has contributed to research in topics: Anterior cingulate cortex & Amygdala. The author has an hindex of 8, co-authored 8 publications receiving 554 citations. Previous affiliations of Xiangyu Zhang include McGovern Institute for Brain Research & Massachusetts Institute of Technology.
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Journal ArticleDOI
Basolateral to Central Amygdala Neural Circuits for Appetitive Behaviors
Joshua Kim,Xiangyu Zhang,Shruti Muralidhar,Sarah Anne LeBlanc,Susumu Tonegawa,Susumu Tonegawa +5 more
TL;DR: Genetically defined neural circuits in the amygdala that promote and suppress appetitive behaviors analogous to the direct and indirect pathways of the basal ganglia are revealed.
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Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects
Yang Zhou,Yang Zhou,Tobias Kaiser,Patricia Monteiro,Patricia Monteiro,Patricia Monteiro,Xiangyu Zhang,Marie Sophie van der Goes,Dongqing Wang,Boaz Barak,Menglong Zeng,Menglong Zeng,Chenchen Li,Chenchen Li,Congyi Lu,Congyi Lu,Michael F. Wells,Michael F. Wells,Aldo Amaya,Shannon Nguyen,Michael C. Lewis,Neville E. Sanjana,Neville E. Sanjana,Yongdi Zhou,Mingjie Zhang,Feng Zhang,Zhanyan Fu,Zhanyan Fu,Guoping Feng,Guoping Feng,Guoping Feng +30 more
TL;DR: In this paper, the authors characterized two lines of mutant mice with Shank3 mutations linked to ASD and schizophrenia and found both shared and distinct synaptic and behavioral phenotypes, which may inform exploration of these relationships in human patients.
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Amygdala Reward Neurons Form and Store Fear Extinction Memory.
TL;DR: It is demonstrated that a fear extinction memory engram is formed and stored in a genetically distinct basolateral amygdala (BLA) neuronal population that drives reward behaviors and antagonizes the BLA's original fear neurons.
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The Anterior Cingulate Cortex Predicts Future States to Mediate Model-Based Action Selection
Thomas Akam,Ines Rodrigues-Vaz,Ivo M. Marcelo,Xiangyu Zhang,Michael Pereira,Rodrigo F. Oliveira,Peter Dayan,Rui M. Costa +7 more
TL;DR: It is shown that the anterior cingulate cortex (ACC) predicts the state that actions will lead to, not simply whether they are good or bad, and monitors whether outcomes match these predictions, and is a critical node in model-based control.
Journal ArticleDOI
A Novel Imprinted Gene NUWA Controls Mitochondrial Function in Early Seed Development in Arabidopsis.
Shan He,Yan Sun,Qian Yang,Xiangyu Zhang,Qingpei Huang,Peng Zhao,Mengxiang Sun,Jingjing Liu,Weiqiang Qian,Genji Qin,Hongya Gu,Li-Jia Qu +11 more
TL;DR: A novel imprinted gene of a previously unidentified type is uncovers, namely, a maternal-specific expressed nuclear gene with its encoded protein localizing to and controlling the function of the maternally inherited mitochondria, which reveals a unique mechanism of maternal control of the mitochondria.