Xiaohua Liu

TL;DR: The development of a new bisguanidinium salt as a multifunctional organocatalyst for asymmetric cascade esterification/aza-Michael reaction between 2-hydroxyphenyl-substituted enones and isocyanates is reported.

TL;DR: Endotoxin tolerance induced by lipopolysaccharide pretreatment was accompanied with upregulation of suppressors of cytokine signalling-1 and the silence of suppressor of cytokinespecifics-1 by RNA interference obviously attenuated this inhibitive effect, indicating that the absence of suppression of IL-1 caused abnormal enhancement of inflammatory cytokine production.

TL;DR: Chiral Lewis acid-promoted enantioselective α-alkylation of β-ketoamides with phenyliodonium ylide with good results was developed and control experiments and EPR studies supported a radical process.

TL;DR: A highly efficient asymmetric Diels-Alder/[3,3] sigmatropic rearrangement reaction of methyleneindolinones with 1-thiocyanatobutadienes has been realized by using a chiral N,N'-dioxide/nickel(II) complex as the catalyst.

TL;DR: In this paper, the mechanism of the aminolysis of meso-epoxides catalyzed by the proline-based N,N′-dioxide-indium tris(triflate) complex was performed using control experiments, UV-Vis spectroscopy, 1H NMR, electrospray ionization mass spectrometry (ESI-MS) and scanning electron microscopy (SEM).