Xiaoxiao Yang

TL;DR: This review will examine and make the case that CO be developed into a therapeutic agent against AKI, a common clinical problem that develops in patients receiving cisplatin therapies for a number of different solid organ malignancies.

TL;DR: The authors show that TRIB3 interacts with EGFR and regulates its stability and activity, and perturbing EGFR-TRIB3 interaction attenuates NSCLC progression by accelerating EGFR degradation.

TL;DR: This work assessed the response of three published arylnitro-based fluorescent CO probes, namely COFP, LysoFP-NO2, and NIR-CO toward CO from various sources and found that only ruthenium-based CO releasing molecules (CO-RMs) were able to turn on the fluorescence while pure CO gas and CO from other sources did not turn-on the probe in the absence of r Ruthenium.

TL;DR: The donor was examined for its inhibitory effect toward glyceraldehyde 3-phosphate dehydrogenase (GAPDH).

TL;DR: The protective effect of representative CO prodrug, BW-CO-111, is examined in rat models of gastric damage induced by necrotic ethanol or aspirin, a representative non-steroidal anti-inflammatory drug.