Y
Yuhan Guo
Researcher at University of Hong Kong
Publications - 11
Citations - 246
Yuhan Guo is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 3, co-authored 5 publications receiving 190 citations. Previous affiliations of Yuhan Guo include Li Ka Shing Faculty of Medicine, University of Hong Kong.
Papers
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Journal ArticleDOI
Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo.
Jun Jacob Hu,Nai-Kei Wong,Sen Ye,Xingmiao Chen,Mingyang Lu,Angela Qian Zhao,Yuhan Guo,Alvin C.H. Ma,Anskar Y.H. Leung,Jiangang Shen,Dan Yang +10 more
TL;DR: Three new O2(•-) fluorescent probes are synthesized which exhibit excellent selectivity and sensitivity over a broad range of pH, strong oxidants, and abundant reductants found in cells, which open up exciting opportunities for unmasking the roles of O2 (•-) in health and disease.
Journal ArticleDOI
Functions of IDH1 and its mutation in the regulation of developmental hematopoiesis in zebrafish
Xiangguo Shi,Bai-Liang He,Alvin C.H. Ma,Yuhan Guo,Yali Chi,Cheuk Him Man,Wenqing Zhang,Yiyue Zhang,Zilong Wen,Tao Cheng,Anskar Y.H. Leung +10 more
TL;DR: It is shown that zebrafish idh1 (zidh1) knockdown by morpholino and targeted mutagenesis by transcription activator-like effector nuclease might induce blockade in myeloid differentiation, as evident by an increase in pu.1 and decrease in mpo, l-plastin, and mpeg1 expression, and significantly reduce definitive hematopoiesis.
Book ChapterDOI
Modeling Tumor Angiogenesis with Zebrafish
TL;DR: The zebrafish model represents an emerging vertebrate system to study the tumor angiogenesis process and to better understand the modification of tumor microenvironment by anti-angiogenesis therapy.
Journal ArticleDOI
Effect of ambient air pollutants on in vitro fertilization-embryo transfer pregnancy outcome in Zhengzhou, China.
TL;DR: Wang et al. as discussed by the authors used multivariate logistic regression to analyze the relationship between six ambient air pollutants (PM2.5, PM10, NO2, SO2, CO and O3) and the IVF-ET pregnancy outcome.
Journal ArticleDOI
Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium
Yuhan Guo,Bowie Yik Ling Cheng,Dandan Wang,Alvin C.H. Ma,Bai-Liang He,Toni K. Man,May P.L. Cheung,Xiangguo Shi,Nelson K. L. Ng,Anskar Y.H. Leung +9 more
TL;DR: This study identified arl4aa as a factor regulating initiation of definitive HSCs by maintaining the integrity of Golgi complex and, secondarily, maturation of the Notch receptor.