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Yan-Ni Shi
Researcher at Goethe University Frankfurt
Publications - 18
Citations - 349
Yan-Ni Shi is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Gene & Xenorhabdus. The author has an hindex of 8, co-authored 15 publications receiving 193 citations. Previous affiliations of Yan-Ni Shi include Chinese Academy of Sciences.
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Journal ArticleDOI
Nonribosomal Peptides Produced by Minimal and Engineered Synthetases with Terminal Reductase Domains.
TL;DR: The biosynthesis of a pyrazine that originates from an aldehyde‐generating minimal NRPS termed ATRed in entomopathogenic Xenorhabdus indica is revealed.
Posted ContentDOI
The Chemical Structure of Widespread Microbial Aryl Polyene Lipids
Gina L. C. Grammbitter,Yi-Ming Shi,Yan-Ni Shi,Sahithya Phani Babu Vemulapalli,Christian Richter,Harald Schwalbe,Mohammad Alanjary,Mohammad Alanjary,Anja Schüffler,Matthias Witt,Christian Griesinger,Helge B. Bode +11 more
TL;DR: In this article, aryl polyene-containing lipids (APELs) from the entomopathogenic bacterium Xenorhabdus doucetiae were analyzed using a combination of isotope labeling, nuclear magnetic resonance techniques, and tandem mass spectrometry.
Posted ContentDOI
Evolution Inspired Engineering of Megasynthetases
Kenan A. J. Bozhüyük,Leonard Präve,Carsten Kegler,Sebastian Kaiser,Yan-Ni Shi,Wolfgang Kuttenlochner,Leonie Schenk,TM Mohiuddin,Michael Groll,Georg K. A. Hochberg,Helge B. Bode +10 more
TL;DR: In this article , an evolution-inspired eXchange Unit between T domains (XUT) approach was developed which allows the assembly of NRPS fragments over a broad range of GC contents, protein similarities, and extender unit specificities.
Journal ArticleDOI
Chemical constituents from Piper hainanense and their cytotoxicities
Yan-Ni Shi,Ying Xin,Yi Ling,Xing-Cong Li,Chao-Yun Hao,Hong-Tao Zhu,Dong Wang,Chong-Ren Yang,Min Xu,Ying-Jun Zhang +9 more
TL;DR: Two new compounds, (Z,R)-1-phenylethylcinnamate and (1R,2R,3R,6S)-pipoxide were isolated from the aerial part of Piper hainanense, along with 12 known compounds, including nine benzene derivatives, one isobutylamide, and two polyoxygenated cyclohexene derivatives (13–14).
Posted ContentDOI
Focused natural product elucidation by prioritizing high-throughput metabolomic studies with machine learning
Nicholas J. Tobias,César Parra-Rojas,Yan-Ni Shi,Yi-Ming Shi,Svenja Simonyi,Aunchalee Thanwisai,Apichat Vitta,Narisara Chantratita,Esteban A. Hernandez-Vargas,Helge B. Bode +9 more
TL;DR: A comprehensive metabolic screening using HPLC-MS data associated with a 114-strain collection from across Thailand and utilizing machine learning in order to rank the importance of individual metabolites in determining all given metadata, leading to the identification of previously unknown compounds.