Yanyan Hou

TL;DR: Following application of ultrasounds to cells treated with BTNPs, fluorescence imaging of ion dynamics revealed that the synergic stimulation is able to elicit a significant cellular response in terms of calcium and sodium fluxes; moreover, tests with appropriate blockers demonstrated that voltage-gated membrane channels are activated.

TL;DR: The first application of a small molecule-type thermosensitive fluorescent dye, ERthermAC, to monitor thermogenesis in BAs derived from murine brown fat precursors and in human brown fat cells differentiated from human neck brown preadipocytes is reported.

TL;DR: Evidence is provided that remote NIR + NS muscle excitation represents an effective wireless stimulation technique with great potential in the fields of muscle tissue engineering, regenerative medicine, and bionics.

TL;DR: It is demonstrated that an increase in mitochondrial pH is implicated as an early event in adrenergically stimulated BAs and suggested that this pH increase may play a role in the potentiation of thermogenesis.

TL;DR: This work proposes a bottom-up approach to generate nanoprobes where four organic dyes are conjugated to tetravalent single-chain avidin (scAVD) proteins via an intracellular click reaction, and demonstrates that the nanoprobs, exhibiting increased brightness and enhanced photostability, were detectable as single dots in living cells.