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Yao-Rong Zheng
Researcher at Kent State University
Publications - 52
Citations - 6657
Yao-Rong Zheng is an academic researcher from Kent State University. The author has contributed to research in topics: Supramolecular chemistry & Prodrug. The author has an hindex of 30, co-authored 48 publications receiving 5932 citations. Previous affiliations of Yao-Rong Zheng include University of Ulsan & North Carolina State University.
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Journal ArticleDOI
Metal–Organic Frameworks and Self-Assembled Supramolecular Coordination Complexes: Comparing and Contrasting the Design, Synthesis, and Functionality of Metal–Organic Materials
Journal ArticleDOI
Self-Organization in Coordination-Driven Self-Assembly
TL;DR: The studies have shown that the extent of self-organization in the coordination-driven self-assembly of both 2D polygons and 3D polyhedra ranges from no organization to amplified organization and all the way to the absolute self- Organization of discrete supramolecular assemblies.
Journal ArticleDOI
Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery
Yao-Rong Zheng,Kogularamanan Suntharalingam,Timothy C. Johnstone,Hyunsuk Yoo,Wei Lin,Jamar G. Brooks,Stephen J. Lippard +6 more
TL;DR: A series of platinum(IV) prodrugs designed specifically to enhance interaction with human serum albumin (HSA) for drug delivery was presented in this article. But, their performance was limited by the fact that the axial ligands of the prodrug were asymmetrically functionalized so as to mimic the overall features of a fatty acid.
Journal ArticleDOI
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug
Miles A. Miller,Yao-Rong Zheng,Suresh Gadde,Christina Pfirschke,Harshal Zope,Camilla Engblom,Rainer H. Kohler,Yoshiko Iwamoto,Katherine S. Yang,Bjorn Askevold,Nagesh Kolishetti,Mikael J. Pittet,Stephen J. Lippard,Omid C. Farokhzad,Omid C. Farokhzad,Ralph Weissleder +15 more
TL;DR: Simultaneous imaging of intratumoral TNP vehicle, its drug payload and single-cell DNA damage response reveals that TAMs serve as a local drug depot that accumulates significant vehicle from which DNA-damaging Pt payload gradually releases to neighbouring tumour cells.
Journal ArticleDOI
A facile approach toward multicomponent supramolecular structures: selective self-assembly via charge separation.
Yao-Rong Zheng,Zhigang Zhao,Ming Wang,Koushik Ghosh,J. Bryant Pollock,Timothy R. Cook,Peter J. Stang +6 more
TL;DR: A novel approach toward the construction of multicomponent two-dimensional and three-dimensional metallosupramolecules by mixing carboxylate and pyridyl ligands with cis-Pt(PEt(3))(2)(OTf)(2) in a proper ratio allows for the selective generation of discrete multicomponents structures via charge separation on the metal centers.