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Yaochen Wang
Researcher at Public Health England
Publications - 10
Citations - 11275
Yaochen Wang is an academic researcher from Public Health England. The author has contributed to research in topics: Breast cancer & Radiation therapy. The author has an hindex of 8, co-authored 10 publications receiving 9477 citations. Previous affiliations of Yaochen Wang include University of Oxford & Clinical Trial Service Unit.
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Journal ArticleDOI
Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials.
Mike Clarke,Rory Collins,Sarah C. Darby,C Davies,P. Elphinstone,V Evans,J Godwin,Richard Gray,C. Hicks,Spencer L. James,E MacKinnon,Paul McGale,T McHugh,Richard Peto,Carolyn W. Taylor,Yaochen Wang +15 more
TL;DR: It is found that variations in local treatment that substantially affect the risk of locoregional recurrence could also affect long-term breast cancer mortality, and that avoidance of a local recurrence in the conserved breast is recommended.
Journal ArticleDOI
Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials
Sarah C. Darby,Paul McGale,C Correa,Carolyn W. Taylor,R Arriagada,Mike Clarke,D Cutter,C Davies,Marianne Ewertz,Jon Godwin,Richard Gray,Lori J. Pierce,Timothy J. Whelan,Yaochen Wang,Richard Peto +14 more
TL;DR: In this paper, the authors conducted a meta-analysis of individual patient data for 10,801 women in 17 randomised trials of radiotherapy versus no radiotherapy after breast-conserving surgery, 8337 of whom had pathologically confirmed node-negative (pN0) or node-positive (nN+) disease.
Journal ArticleDOI
Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial
C Davies,Hongchao Pan,Jon Godwin,Richard Gray,Rodrigo Arriagada,Vinod Raina,Mirta Abraham,Victor Hugo Medeiros Alencar,Atef Badran,Xavier Bonfill,Joan Caroline Bradbury,Mike Clarke,Rory Collins,Susan R. Davis,Antonella Delmestri,John F. Forbes,Peiman Haddad,Ming-Feng Hou,Moshe Inbar,Hussein M. Khaled,Joanna Kielanowska,Wing-Hong Kwan,Beela Sarah Mathew,Indraneel Mittra,Bettina Muller,Antonio Nicolucci,Octavio Peralta,Fany Pernas,Lubos Petruzelka,Tadeusz Pienkowski,Ramachandran Radhika,Balakrishnan Rajan,Maryna Rubach,Sera Tort,Gerard Urrútia,Miriam Valentini,Yaochen Wang,Richard Peto +37 more
TL;DR: Treatment allocation seemed to have no effect on breast cancer outcome among 1248 women with ER-negative disease, and an intermediate effect among 4800 women with unknown ER status, and a further reduction in recurrence and mortality, particularly after year 10.
Journal ArticleDOI
Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials
Bernard Asselain,William E. Barlow,John M. S. Bartlett,Jonas Bergh,Elizabeth Bergsten-Nordström,Judith M Bliss,Francesco Boccardo,Clare Boddington,Jan Bogaerts,Gianni Bonadonna,Rosie Bradley,Etienne Brain,Jeremy P Braybrooke,Philippe Broët,John Bryant,Julie Ann Burrett,David Cameron,Mike Clarke,Alan S. Coates,Robert E. Coleman,Raoul Charles Coombes,C Correa,J. Costantino,Jack Cuzick,David N. Danforth,Nancy E. Davidson,C Davies,Lucy Davies,Angelo Di Leo,David Dodwell,Mitch Dowsett,Fran Duane,Vaughan Evans,Marianne Ewertz,Bernard Fisher,John F. Forbes,Leslie G. Ford,Jean-Claude Gazet,Richard D. Gelber,Lucy Gettins,Luca Gianni,Michael Gnant,Jon Godwin,Aron Goldhirsch,Pamela J. Goodwin,Richard Gray,Daniel F. Hayes,Catherine Hill,James N. Ingle,Reshma Jagsi,Raimund Jakesz,Sam James,Wolfgang Janni,Hui Liu,Z Liu,Caroline Lohrisch,Sibylle Loibl,Liz MacKinnon,Andreas Makris,Eleftherios P. Mamounas,Gurdeep S. Mannu,Miguel Martín,Simone Mathoulin,Louis Mauriac,Paul McGale,Theresa McHugh,Philip Morris,Hirofumi Mukai,Larry Norton,Yasuo Ohashi,Ivo A. Olivotto,Soon Paik,Hongchao Pan,Richard Peto,Martine Piccart,Lori J. Pierce,Philip Poortmans,Trevor J. Powles,Kathy Pritchard,Joseph Ragaz,Vinod Raina,Peter M. Ravdin,Simon Read,Meredith M. Regan,John F.R. Robertson,Emiel J. Th. Rutgers,Suzy Scholl,Dennis J. Slamon,Lidija Sölkner,Joseph A. Sparano,Seth M. Steinberg,Rosemary Sutcliffe,Sandra M. Swain,Carolyn W. Taylor,Andrew Tutt,Pinuccia Valagussa,Cornelis J.H. van de Velde,Jos van der Hage,Giuseppe Viale,Gunter von Minckwitz,Yaochen Wang,Zhe Wang,Xiang Wang,Timothy J. Whelan,Nicholas Wilcken,Eric P. Winer,Norman Wolmark,William C. Wood,Milvia Zambetti,Jo Anne Zujewski +109 more
TL;DR: Tumours downsized by NACT might have higher local recurrence after breast-conserving therapy than might tumours of the same dimensions in women who have not received NACT.
Journal ArticleDOI
Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast
C Correa,Paul McGale,Carolyn W. Taylor,Yaochen Wang,Mike Clarke,C Davies,Richard Peto,N Bijker,L Solin,Sarah C. Darby +9 more
TL;DR: Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive cancer) by 15.2% and was effective regardless of the age at diagnosis, extent of breast-conserving surgery, use of tamoxifen, method of DCIS detection, margin status, focality, grade, comedonecrosis, architecture, or tumor size.