Y
Yinghui Zheng
Researcher at Peking University
Publications - 9
Citations - 1385
Yinghui Zheng is an academic researcher from Peking University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 5 publications receiving 910 citations.
Papers
More filters
Journal ArticleDOI
Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
Y Cao,Bin Su,Xianghua Guo,Wenjie Sun,Yong-Qiang Deng,Linlin Bao,Qinyu Zhu,Xu Zhang,Yinghui Zheng,Chenyang Geng,Xiaoran Chai,Runsheng He,Xiaofeng Li,Qi Lv,Hua Zhu,Wei Deng,Yanfeng Xu,Yanjun Wang,Luxin Qiao,Yafang Tan,Liyang Song,Guopeng Wang,Xiao-Xia Du,Ning Gao,Jiangning Liu,Junyu Xiao,Xiao-Dong Su,Zongmin Du,Yingmei Feng,Chuan Qin,Cheng-Feng Qin,Ronghua Jin,X. Sunney Xie +32 more
TL;DR: It is shown that human neutralizing antibodies could be efficiently discovered by high-throughput single B-cell sequencing in response to pandemic infectious diseases.
Journal ArticleDOI
Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Shuo Du,Y Cao,Qinyu Zhu,Pin Yu,Feifei Qi,Guopeng Wang,Xiao-Xia Du,Linlin Bao,Wei Deng,Hua Zhu,Jiangning Liu,Jianhui Nie,Yinghui Zheng,Haoyu Liang,Ruixue Liu,Shuran Gong,Hua Xu,Ayijiang Yisimayi,Qi Lv,Bo Wang,Runsheng He,Yunlin Han,Wenjie Zhao,Yali Bai,Yajin Qu,Xiang Gao,Chenggong Ji,Qisheng Wang,Ning Gao,Weijin Huang,Youchun Wang,X. Sunney Xie,Xiao-Dong Su,Junyu Xiao,Chuan Qin +34 more
TL;DR: The results rationalized a new RBD epitope that leads to high neutralization potency and demonstrated BD-368-2’s therapeutic potential in treating COVID-19, a SARS-CoV-2 pseudovirus at pM level and rescues mutation-induced neutralization escapes.
Journal ArticleDOI
Changes in genome architecture and transcriptional dynamics progress independently of sensory experience during post-natal brain development.
Longzhi Tan,Longzhi Tan,Wenping Ma,Honggui Wu,Yinghui Zheng,Dong Xing,Ritchie Chen,Xiang Li,Nicholas Daley,Karl Deisseroth,Karl Deisseroth,X. Sunney Xie +11 more
TL;DR: In this article, a 3D atlas of the developing mouse cortex and hippocampus was generated by using high-resolution multiple annealing and looping-based amplification cycles for digital transcriptomics (MALBAC-DT) and diploid chromatin conformation capture (Dip-C) methods and developing multi-omic analysis pipelines.
Journal ArticleDOI
Lycium barbarum Glycopeptide prevents the development and progression of acute colitis by regulating the composition and diversity of the gut microbiota in mice
Yi-Chen Huang,Yinghui Zheng,Yicheng Feng,K Xu,Jun Wu,Shuang Qu,Zhexiong Yu,Fuxiang Fan,Lu Huang,Meng Qin,Zhan He,Kaili Nie,Kwok-Fai So +12 more
TL;DR: The capability of LbGP to prevent the development of acute colitis by regulating the composition and diversity of the gut microbiota and highlighted the dynamic process of gut microbiota with the colitis progression is demonstrated.
Posted ContentDOI
Structures of potent and convergent neutralizing antibodies bound to the SARS-CoV-2 spike unveil a unique epitope responsible for exceptional potency
Shuo Du,Y Cao,Qinyu Zhu,Guopeng Wang,Xiao-Xia Du,Runsheng He,Hua Xu,Yinghui Zheng,Bo Wang,Yali Bai,Chenggong Ji,Ayijiang Yisimayi,Qisheng Wang,Ning Gao,Sunney Xie,Xiao-Dong Su,Junyu Xiao +16 more
TL;DR: The results rationalize a unique epitope that leads to exceptional neutralization potency, and provide guidance for NAb therapeutics and vaccine designs against SARS-CoV-2.