Xu Zhang

TL;DR: It is shown that human neutralizing antibodies could be efficiently discovered by high-throughput single B-cell sequencing in response to pandemic infectious diseases.

TL;DR: In this article, a modulation multiplexing approach was proposed for real-time detection of multiple species using the fast Fourier transform (FFT) for labeling and quantifying chemical concentrations in a ternary mixture.

TL;DR: It is demonstrated that quantitative concentration determination of cholesterol in the presence of interfering chemical species can be achieved with sensitivity down to 4 mM, and it is shown that mammalian cell SRS hyperspectral imaging reveals the spatially inhomogeneous distribution of saturated lipids, unsaturatedlipids, cholesterol, and protein.

TL;DR: A model in which rhabduscin’s physical association at the bacterial cell surface provides a highly effective inhibitor concentration directly at the site of phenoloxidase contact is suggested, which is not limited to insect pathogens.

TL;DR: SRS imaging in the fingerprint region is demonstrated to be able to map the distribution of nucleic acids in addition to proteins and lipids in single salivary gland cells of Drosophila larvae, and in single mammalian cells, opening up possibilities of imaging such processes in vivo.