Y
Youngmi Kim Pak
Researcher at Kyung Hee University
Publications - 134
Citations - 4964
Youngmi Kim Pak is an academic researcher from Kyung Hee University. The author has contributed to research in topics: Mitochondrion & Insulin resistance. The author has an hindex of 37, co-authored 128 publications receiving 4456 citations. Previous affiliations of Youngmi Kim Pak include Stanford University & Kangwon National University.
Papers
More filters
Journal ArticleDOI
Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells.
Young Min Cho,Sujin Kwon,Youngmi Kim Pak,Hye Won Seol,Young Min Choi,Do Joon Park,Kyong Soo Park,Hong Kyu Lee +7 more
TL;DR: HESC differentiation was followed by dynamic changes in mitochondrial mass, ATP and ROS production, and antioxidant enzyme expressions, which led to a dramatic change in the expression of various antioxidant enzymes.
Journal ArticleDOI
Oxidized Low Density Lipoprotein Inhibits Interleukin-12 Production in Lipopolysaccharide-activated Mouse Macrophages via Direct Interactions between Peroxisome Proliferator-activated Receptor-γ and Nuclear Factor-κB
Su Wol Chung,Bok Yun Kang,Seung Hyun Kim,Youngmi Kim Pak,Daeho Cho,Giorgio Trinchieri,Tae Sung Kim +6 more
TL;DR: OxLDL-mediated suppression of the IL-12 production from LPS-activated mouse macrophages may, at least in part, involve both inhibition of the NF-κB-DNA interactions and physical interactions between NF-σκB and PPAR-γ.
Journal ArticleDOI
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
Min-Seon Kim,Youngmi Kim Pak,Pil-Geum Jang,Cherl Namkoong,Yon-Sik Choi,Jong Chul Won,Kyung-Sup Kim,Seung-Whan Kim,Hyo-Soo Kim,Joong-Yeol Park,Young-Bum Kim,Ki-Up Lee +11 more
TL;DR: It is demonstrated that in normal mice, hypothalamic Foxo1 expression is reduced by the anorexigenic hormones insulin and leptin, establishing a new signaling pathway through which insulin andptin regulate food intake in hypothalamic neurons.
Journal ArticleDOI
The Mitogenic and Antiapoptotic Actions of Ghrelin in 3T3-L1 Adipocytes
Min Seon Kim,Cho Ya Yoon,Pil Geum Jang,Young Joo Park,Chan Soo Shin,Hye Sun Park,Je Won Ryu,Youngmi Kim Pak,Joong Yeol Park,Ki Up Lee,Seong Yeon Kim,Hong Kyu Lee,Young-Bum Kim,Kyong Soo Park +13 more
TL;DR: The findings suggest that the direct effects of ghrelin on proliferation, differentiation, and apoptosis in adipocytes may play a role in regulating fat cell number, which may be mediated via activation of the MAPK and phosphatidylinositol 3-kinase/Akt pathways.
Journal ArticleDOI
Chronic Exposure to the Herbicide, Atrazine, Causes Mitochondrial Dysfunction and Insulin Resistance
Soo Lim,Sun Young Ahn,In Chan Song,Myung Hee Chung,Hak Chul Jang,Kyong Soo Park,Ki Up Lee,Youngmi Kim Pak,Hong Kyu Lee +8 more
TL;DR: It is suggested that long-term exposure to the herbicide ATZ might contribute to the development of insulin resistance and obesity, particularly where a high-fat diet is prevalent.