Y
Yuji Miyahara
Researcher at Tokyo Medical and Dental University
Publications - 343
Citations - 7756
Yuji Miyahara is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Field-effect transistor & Membrane. The author has an hindex of 47, co-authored 332 publications receiving 7045 citations. Previous affiliations of Yuji Miyahara include National Institute for Materials Science & Kyushu University.
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Design of an open-tubular column liquid chromatograph using silicon chip technology
TL;DR: In this article, a silicon chip with an open-tubular column and a conductometric detector, a chip holder and a pressure pulse driven injector using a conventional liquid chromatography pump and valves is presented, which has theoretical separation efficiencies of 8000 and 25 000 plates in 1 and 5 min, respectively.
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Phenylboronic Acid-Installed Polymeric Micelles for Targeting Sialylated Epitopes in Solid Tumors
Stephanie Deshayes,Horacio Cabral,Takehiko Ishii,Yutaka Miura,Shutaro Kobayashi,Takashi Yamashita,Akira Matsumoto,Yuji Miyahara,Nobuhiro Nishiyama,Kazunori Kataoka +9 more
TL;DR: Developed PBA-installed micellar nanocarriers incorporating the parent complex of the anticancer drug oxaliplatin for targeting sialylated epitopes overexpressed on cancer cells, which effectively reduced the growth rate of both orthotopic and lung metastasis models of melanoma.
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A Synthetic Approach Toward a Self‐Regulated Insulin Delivery System
Akira Matsumoto,Takehiko Ishii,Junko Nishida,Hiroko Matsumoto,Kazunori Kataoka,Yuji Miyahara +5 more
TL;DR: PBA, a synthetic molecule capable of reversibly binding with 1,2or 1,3-cis-diols including glucose, is utilized as the molecular basis and systemically explored the structure–property correlation by focusing on (meth)acrylamide-based hydrogels.
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A phenylboronate-functionalized polyion complex micelle for ATP-triggered release of siRNA
TL;DR: It is demonstrated that the PBA-assisted PIC micelles can be tailored to exhibit a dramatic disruption accompanied by the release of siRNAs in response to a change in the ribose concentration (which parallels events in the intracellular environment).
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Noninvasive sialic acid detection at cell membrane by using phenylboronic acid modified self-assembled monolayer gold electrode.
TL;DR: A potentiometric SA detection using a phenylboronic acid compound integrated into the form of a self-assembled monolayer (SAM) onto a field effect transistor (FET) extended gold gate electrode is developed, revealing that the disease could be feasibly diagnosed simply by placing the known-count cell suspensions onto the device without any labeling and enzymatic procedures.