Yumin Yang

TL;DR: Different nerve grafts used for peripheral nerve repair are summarized, various basic components of tissue engineered nerve grafting are highlighted in terms of their structures, features, and nerve regeneration-promoting actions, and current clinical applications and future perspectives are discussed.

TL;DR: Data indicate that silk fibroin has good biocompatibility with DRG and is also beneficial to the survival of Schwann cells without exerting any significant cytotoxic effects on their phenotype or functions, thus providing an experimental foundation for the development of silk Fibroin as a candidate material for nerve tissue engineering applications.

TL;DR: Functional and morphological parameters show that SF grafts could promote peripheral nerve regeneration with effects approaching those elicited by nerve autografts which are generally considered as the gold standard for treating large peripheral nerve defects, thus raising a potential possibility of using these newly developed nerve grafts as a promising alternative to nerve autOGrafts.

TL;DR: The results from morphological analysis as well as electrophysiological examination indicated that regenerative outcomes achieved by the developed scaffold were similar to an acellular nerve graft, but superior to those by a plain chitosan/SF scaffold.

TL;DR: Comparative genomic analysis reveals specific gene family expansions or reductions that are associated with the formation of adhesive setae, nocturnal vision and tail regeneration, as well as the diversification of olfactory sensation that provide robust genetic evidence of adaptive evolution in reptiles.