Yun Ling

TL;DR: Patients with fever and/or cough and with conspicuous ground-glass opacity lesions in the peripheral and posterior lungs on CT images, combined with normal or decreased white blood cells and a history of epidemic exposure, are highly suspected of having 2019 Novel Coronavirus (2019-nCoV) pneumonia.

TL;DR: The clearance time and factors influencing 2019 novel coronavirus (2019-nCoV) RNA in different samples from patients with COVID-19 were analyzed, providing further evidence to improve the management of patients during convalescence and showed that the CD4+ T lymphocyte count may help predict the duration of viral RNA detection in patients’ stools.

TL;DR: Clinical data from 326 cases suggest that T cell depletion and cytokine bursts are associated with a worse prognosis, and genomic sequences from 112 patients with confirmed SARS-CoV-2 virus showed two clades with similar virulence and clinical outcome.

TL;DR: Multiple organ dysfunction and impaired immune function were the typical characteristics of patients with severe or critical illness and there was a significant difference in the use of angiotensin-converting enzyme inhibitors/angiotens in II receptor blockers among patients with different severities of disease.

TL;DR: The clinical progression pattern suggests that early control of viral replication and application of host-directed therapy in later stage is essential to improve the prognosis of CVOID-19.