Yves Traoré

TL;DR: Analyzing the isotypic distribution of the IgG response to conserved epitopes and P. falciparum blood-stage extract in 283 malaria-exposed individuals favors a protective role of IgG3 and IgG2, which may activate effector cells through FcγRIIA, and provides evidence for a blocking role for IgG4 in malarial infection and disease.

TL;DR: In this article, the authors evaluated the usefulness of field-based polymerase chain reaction (PCR) testing to identify the etiologic agent in cases of bacterial meningitis in sub-Saharan Africa.

TL;DR: Sib-pair linkage analyses between blood infection levels and chromosome 5q31-q33, which contains numerous candidate genes encoding immunological molecules indicate that the locus plays a central role in the control of parasitemia, and the identification of the gene is of major interest in understanding the mechanisms controlling P. falciparum Parasitemia.

TL;DR: Although a serotype 1 clone was commonly isolated, over half of the cases were caused by other serogroups and/or serotypes, and genetic diversification increased over a relatively short period.

TL;DR: High genetic diversity in hepatitis C virus (HCV) and its genotypes implies that HCV infection is long‐established in these West African regions and poses a challenge for vaccine development.