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Ze-Guang Han

Researcher at Shanghai Jiao Tong University

Publications -  191
Citations -  10954

Ze-Guang Han is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Gene & Carcinogenesis. The author has an hindex of 45, co-authored 184 publications receiving 9319 citations. Previous affiliations of Ze-Guang Han include East China University of Science and Technology & Chinese National Human Genome Center.

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Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection.

TL;DR: This study constructed a risk map indicating the vulnerability of different organs to 2019-nCoV infection, and identified the organs at risk, such as lung, heart, esophagus, kidney, bladder, and ileum, and located specific cell types (i.e., type II alveolar cells (AT2), myocardial cells, proximal tubule cells of the kidney, ileal cells, and bladder urothelial cells).
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Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain

TL;DR: CDNA array on genes mainly made from the cDNA libraries of lumbar DRGs of normal rats and of rats 14 days after peripheral axotomy reveals dynamic and complex changes in molecular diversity among DRG neurons after axotomy.
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Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver.

TL;DR: In this paper, a comprehensive characterization of gene expression profiles of hepatitis B virus-positive HCC through the generation of a large set of 5′-read expressed sequence tag (EST) clusters (11,065 in total) from HCC and non-cancerous liver samples, which then were applied to a cDNA microarray system containing 12,393 genes/ESTs and to comparison with a public database.
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Exome sequencing of hepatitis B virus–associated hepatocellular carcinoma

TL;DR: Exome sequencing is used to identify somatic mutations in HBV-positive individuals with HCC with portal vein tumor thromboses (PVTTs), intrahepatic metastases and suggests that seven genes, including VCAM1 and CDK14, may confer growth and infiltration capacity to HCC cells.