Z
Zhangzhi Xue
Researcher at Westlake University
Publications - 10
Citations - 37
Zhangzhi Xue is an academic researcher from Westlake University. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 2, co-authored 3 publications receiving 8 citations.
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Journal ArticleDOI
Computational Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage and Applications to 15 Tumors.
Weigang Ge,Xiao Liang,Fangfei Zhang,Yifan Hu,Luang Xu,Nan Xiang,Rui Sun,Wei Liu,Zhangzhi Xue,Xiao Yi,Yaoting Sun,Bo Wang,Jiang Zhu,Cong Lu,Xiaolu Zhan,Lirong Chen,Yan Wu,Zhiguo Zheng,Wangang Gong,Qijun Wu,Yu Jiekai,Zhaoming Ye,X D Teng,Shiang Huang,Shu Zheng,Tong Liu,Chunhui Yuan,Tiannan Guo +27 more
TL;DR: In this paper, a computational strategy for optimizing the spectral library for a specific DIA data set based on a comprehensive spectral library, requiring the preliminary analysis of the DIA-MS data set, is described.
Journal ArticleDOI
High-throughput proteomic sample preparation using pressure cycling technology
X. Cai,Zhangzhi Xue,Chunlong Wu,Rui Sun,Liujia Qian,Liang Yue,Weigang Ge,Xiaoli Yi,Wei Li,Chen Chen,Huanhuan Gao,Jing-song-di Yu,Lu Ang Xu,Yi Zhu,Tiannan Guo +14 more
TL;DR: In this article , a detailed protocol of pressure cycling technology (PCT)-assisted sample preparation for proteomic analysis of biopsy tissues is described, where a piece of fresh frozen or formalin-fixed paraffin-embedded tissue weighing ~0.1-2 mg is placed in a 150 μL pressure-resistant tube called a PCT-MicroTube with proper lysis buffer.
Journal ArticleDOI
ProteomeExpert: a docker image based web-server for exploring, modeling, visualizing, and mining quantitative proteomic data sets.
Tiansheng Zhu,Hao Chen,Xishan Yan,Zhicheng Wu,Xiaoxu Zhou,Qi Xiao,Weigang Ge,Qiushi Zhang,Chao Xu,Luang Xu,Guan Ruan,Zhangzhi Xue,Chunhui Yuan,Guo-Bo Chen,Tiannan Guo +14 more
TL;DR: ProteomeExpert as discussed by the authors is a web server-based software tool implemented in Docker, which offers various analysis tools for experimental design, data mining, interpretation, and visualization of quantitative proteomic data sets.
Posted ContentDOI
Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage
Weigang Ge,Xiao Liang,Fangfei Zhang,Luang Xu,Nan Xiang,Rui Sun,Wei Liu,Zhangzhi Xue,Xiao Yi,Bei Wang,Jingtan Zhu,Cong Lu,Zhan X,Chen L,Yaosen Wu,Zhiyong Zheng,Weikang Gong,Wu Q,Yu Jiekai,Zhenqing Ye,X D Teng,Shiang Huang,Zheng S,Tingting Liu,Chunhui Yuan,Tiannan Guo +25 more
TL;DR: A computational strategy for optimizing the spectral library for a specific DIA dataset based on a comprehensive spectral library, which is accomplished by a priori analysis of the DIA datasets to achieve deeper proteome coverage of DIA-MS data.
Journal ArticleDOI
Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility
Fengzhe Xu,Evan Yi-Wen Yu,X. Cai,Liang Yue,Li-peng Jing,Xinxiu Liang,Yuanqing Fu,Zelei Miao,M. Yang,Menglei Shuai,Wanglong Gou,Congmei Xiao,Zhangzhi Xue,Yuting Xie,Sainan Li,Shan Lu,Meiqi Shi,Xu-hong Wang,Wenshen Hu,Claudia Langenberg,Jian Yang,Yu-ming Chen,Tiannan Guo,Ju-Sheng Zheng +23 more
TL;DR: This article conducted genome-wide association analyses for 304 unique proteins in 2,958 Han Chinese participants and identified 195 genetic variant-protein associations, which contributed to the differences in the obesity-induced diabetes and coronary artery disease susceptibility.