Z
Zhi-Gao Xu
Researcher at Wuhan University
Publications - 4
Citations - 564
Zhi-Gao Xu is an academic researcher from Wuhan University. The author has contributed to research in topics: Internal medicine & Carcinogenesis. The author has an hindex of 2, co-authored 2 publications receiving 341 citations.
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Journal ArticleDOI
m 6 A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
Jun Liu,Jun Liu,Mark A. Eckert,Bryan T. Harada,Bryan T. Harada,Song-Mei Liu,Zhike Lu,Zhike Lu,Kangkang Yu,Kangkang Yu,Kangkang Yu,Samantha M. Tienda,Agnieszka Chryplewicz,Allen Zhu,Allen Zhu,Ying Yang,Jing-Tao Huang,Shao-Min Chen,Zhi-Gao Xu,Xiao-Hua Leng,Xue-Chen Yu,Jie Cao,Zezhou Zhang,Jianzhao Liu,Ernst Lengyel,Chuan He,Chuan He +26 more
TL;DR: Investigation of human endometrial cancer in which a hotspot R298P mutation is present in a key component of the methyltransferase complex reveals reduced m6A mRNA methylation as an oncogenic mechanism in endometricrial cancer and identifies m 6A methylationAs a regulator of AKT signalling.
Journal ArticleDOI
Next generation digital PCR measurement of hepatitis B virus copy number in formalin-fixed paraffin-embedded hepatocellular carcinoma tissue.
Jing-Tao Huang,Ying-Juan Liu,Jin Wang,Zhi-Gao Xu,Ying Yang,Fan Shen,Xing-hui Liu,Xin Zhou,Song-Mei Liu +8 more
TL;DR: HBV infection is a key factor that influences tumorigenesis in HCC by regulating tumor occurrence and development and ddPCR improves the analytical sensitivity and specificity of measurements in nucleic acids at a single-molecule level and is suitable for HBV detection.
Journal ArticleDOI
IL‐36γ and IL‐36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell–Matrix Adhesion Network and Wnt Signaling
Wei Yang,H.P. Dong,Peng Wang,Zhi-Gao Xu,Jiahuan Xian,Jiachen Chen,Hai-Yan Wu,Yang Lou,Dandan Lin,Bo Zhong +9 more
TL;DR: The findings suggest the critical role of IL‐36γ and IL-36Ra in gut inflammation and tumorigenesis and indicate that targeting the IL‐ 36γ/IL‐36Ra signal balance provides potential therapeutic strategy for inflammatory bowel disease and gastrointestinal cancers.
Journal ArticleDOI
Effect of Matrix Metalloproteinase 23 Accelerating Wound Healing Induced by Hydroxybutyl Chitosan.
Haoyang Xia,Qianchao Hu,Yi Yang,Haoran Yuan,Yan Cai,Zhongzhong Liu,Zhi-Gao Xu,Yan Xiong,Jinping Zhou,Qifa Ye,Zibiao Zhong +10 more
TL;DR: Wang et al. as discussed by the authors revealed the underlying mechanism of matrix metalloproteinase 23 (MMP23) in the dynamic process of cutaneous proliferation and repair period, and they leaded in adeno-associated virus (AAV) to specifically decreased expression quantity of MMP23 in rat skin.