Brookhaven National Laboratory

About: Brookhaven National Laboratory is a facility organization based out in Upton, New York, United States. It is known for research contribution in the topics: Quantum chromodynamics & Scattering. The organization has 18828 authors who have published 39450 publications receiving 1782061 citations. The organization is also known as: BNL.

Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR

Abstract: Binding of virus particles to specific host cell surface receptors is known to be an obligatory step in infection even though the molecular basis for these interactions is not well characterized. The crystal structure of the adenovirus fiber knob domain in complex with domain I of its human cellular receptor, coxsackie and adenovirus receptor (CAR), is presented here. Surface-exposed loops on knob contact one face of CAR, forming a high-affinity complex. Topology mismatches between interacting surfaces create interfacial solvent-filled cavities and channels that may be targets for antiviral drug therapy. The structure identifies key determinants of binding specificity, which may suggest ways to modify the tropism of adenovirus-based gene therapy vectors.

Simultaneously Dual Modification of Ni-Rich Layered Oxide Cathode for High-Energy Lithium-Ion Batteries

Abstract: A critical challenge in the commercialization of layer-structured Ni-rich materials is the fast capacity drop and voltage fading due to the interfacial instability and bulk structural degradation of the cathodes during battery operation. Herein, with the guidance of theoretical calculations of migration energy difference between La and Ti from the surface to the inside of LiNi0.8Co0.1Mn0.1O2, for the first time, Ti-doped and La4NiLiO8-coated LiNi0.8Co0.1Mn0.1O2 cathodes are rationally designed and prepared, via a simple and convenient dual-modification strategy of synchronous synthesis and in situ modification. Impressively, the dual modified materials show remarkably improved electrochemical performance and largely suppressed voltage fading, even under exertive operational conditions at elevated temperature and under extended cutoff voltage. Further studies reveal that the nanoscale structural degradation on material surfaces and the appearance of intergranular cracks associated with the inconsistent evolution of structural degradation at the particle level can be effectively suppressed by the synergetic effect of the conductive La4NiLiO8 coating layer and the strong TiO bond. The present work demonstrates that our strategy can simultaneously address the two issues with respect to interfacial instability and bulk structural degradation, and it represents a significant progress in the development of advanced cathode materials for high-performance lithium-ion batteries.

Azimuthal anisotropy in Au+Au collisions at sNN=200GeV

Abstract: The results from the STAR Collaboration on directed flow (v(1)), elliptic flow (v(2)), and the fourth harmonic (v(4)) in the anisotropic azimuthal distribution of particles from Au+Au collisions at root s(NN) = 200 GeV are summarized and compared with results from other experiments and theoretical models. Results for identified particles are presented and fit with a blast-wave model. Different anisotropic flow analysis methods are compared and nonflow effects are extracted from the data. For v(2), scaling with the number of constituent quarks and parton coalescence are discussed. For v(4), scaling with v(2)(2) and quark coalescence are discussed.

PHENIX detector overview

Abstract: The PHENIX detector is designed to perform a broad study of A-A, p-A, and p-p collisions to investigate nuclear matter under extreme conditions A wide variety of probes, sensitive to all timescales, are used to study systematic variations with species and energy as well as to measure the spin structure of the nucleon Designing for the needs of the heavy-ion and polarized-proton programs has produced a detector with unparalleled capabilities PHENIX measures electron and muon pairs, photons, and hadrons with excellent energy and momentum resolution The detector consists of a large number of subsystems that are discussed in other papers in this volume The overall design parameters of the detector are presented (C) 2002 Elsevier Science BV All rights reserved