Institution
Clark Atlanta University
Education•Atlanta, Georgia, United States•
About: Clark Atlanta University is a education organization based out in Atlanta, Georgia, United States. It is known for research contribution in the topics: Neutrino & Neutrino detector. The organization has 1176 authors who have published 2128 publications receiving 56172 citations. The organization is also known as: CAU.
Papers published on a yearly basis
Papers
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TL;DR: The condition of self-adjointness as discussed by the authors ensures that the eigenvalues of a Hamiltonian are real and bounded below, replacing this condition by the weaker condition of $\mathrm{PT}$ symmetry, one obtains new infinite classes of complex Hamiltonians whose spectra are also real and positive.
Abstract: The condition of self-adjointness ensures that the eigenvalues of a Hamiltonian are real and bounded below. Replacing this condition by the weaker condition of $\mathrm{PT}$ symmetry, one obtains new infinite classes of complex Hamiltonians whose spectra are also real and positive. These $\mathrm{PT}$ symmetric theories may be viewed as analytic continuations of conventional theories from real to complex phase space. This paper describes the unusual classical and quantum properties of these theories.
5,626 citations
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TL;DR: Results from an analysis with a third year of data from the complete IceCube detector are consistent with the previously reported astrophysical flux in the 100 TeV-PeV range at the level of 10(-8) GeV cm-2 s-1 sr-1 per flavor and reject a purely atmospheric explanation for the combined three-year data at 5.7σ.
Abstract: A search for high-energy neutrinos interacting within the IceCube detector between 2010 and 2012 provided the first evidence for a high-energy neutrino flux of extraterrestrial origin. Results from an analysis using the same methods with a third year (2012-2013) of data from the complete IceCube detector are consistent with the previously reported astrophysical flux in the 100 TeV-PeV range at the level of 10(-8) GeV cm(-2) s(-1) sr(-1) per flavor and reject a purely atmospheric explanation for the combined three-year data at 5.7 sigma. The data are consistent with expectations for equal fluxes of all three neutrino flavors and with isotropic arrival directions, suggesting either numerous or spatially extended sources. The three-year data set, with a live time of 988 days, contains a total of 37 neutrino candidate events with deposited energies ranging from 30 to 2000 TeV. The 2000-TeV event is the highest-energy neutrino interaction ever observed.
1,183 citations
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TL;DR: These two neutrino-induced events could be a first indication of an astrophysical neutrinos flux; the moderate significance, however, does not permit a definitive conclusion at this time.
Abstract: We report on the observation of two neutrino-induced events which have an estimated deposited energy in the IceCube detector of 1.04 +/- 0.16 and 1.14 +/- 0.17 PeV, respectively, the highest neutrino energies observed so far. These events are consistent with fully contained particle showers induced by neutral-current nu(e,mu,tau) ((nu) over bar (e,mu,tau)) or charged-current nu(e) ((nu) over bar (e)) interactions within the IceCube detector. The events were discovered in a search for ultrahigh energy neutrinos using data corresponding to 615.9 days effective live time. The expected number of atmospheric background is 0.082 +/- 0.004(stat)(-0.057)(+0.041)(syst). The probability of observing two or more candidate events under the atmospheric background-only hypothesis is 2.9 x 10(-3) (2.8 sigma) taking into account the uncertainty on the expected number of background events. These two events could be a first indication of an astrophysical neutrino flux; the moderate significance, however, does not permit a definitive conclusion at this time.
786 citations
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University of Kentucky1, Yonsei University2, University of Colorado Boulder3, University of Florida4, University of Pennsylvania5, Sungkyunkwan University6, Meharry Medical College7, University of Southern California8, Clark Atlanta University9, Australian National University10, University of Sydney11, Rockefeller University12, New York University13, University of Utah14, Veterans Health Administration15, Johns Hopkins University16, Laval University17
TL;DR: Findings reveal a miRNA-independent cell survival function for DICER1 involving retrotransposon transcript degradation, show that Alu RNA can directly cause human pathology, and identify new targets for a major cause of blindness.
Abstract: Geographic atrophy (GA), an untreatable advanced form of age-related macular degeneration, results from retinal pigmented epithelium (RPE) cell degeneration. Here we show that the microRNA (miRNA)-processing enzyme DICER1 is reduced in the RPE of humans with GA, and that conditional ablation of Dicer1, but not seven other miRNA-processing enzymes, induces RPE degeneration in mice. DICER1 knockdown induces accumulation of Alu RNA in human RPE cells and Alu-like B1 and B2 RNAs in mouse RPE. Alu RNA is increased in the RPE of humans with GA, and this pathogenic RNA induces human RPE cytotoxicity and RPE degeneration in mice. Antisense oligonucleotides targeting Alu/B1/B2 RNAs prevent DICER1 depletion-induced RPE degeneration despite global miRNA downregulation. DICER1 degrades Alu RNA, and this digested Alu RNA cannot induce RPE degeneration in mice. These findings reveal a miRNA-independent cell survival function for DICER1 involving retrotransposon transcript degradation, show that Alu RNA can directly cause human pathology, and identify new targets for a major cause of blindness.
590 citations
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508 citations
Authors
Showing all 1182 results
Name | H-index | Papers | Citations |
---|---|---|---|
George Japaridze | 82 | 382 | 22222 |
Hans E. Grossniklaus | 63 | 612 | 17255 |
Albert Padwa | 61 | 714 | 19902 |
Dirk Lennarz | 61 | 221 | 12891 |
O. Fadiran | 55 | 130 | 12798 |
John Heise | 54 | 327 | 17961 |
Isaac Elishakoff | 47 | 460 | 9144 |
Fereydoon Family | 40 | 196 | 8070 |
Lance M. Kaplan | 39 | 254 | 5848 |
Don VanDerveer | 35 | 279 | 5198 |
Ronald E. Mickens | 35 | 253 | 5733 |
Cleber Renato Mendonça | 34 | 360 | 5195 |
Christian Bosshard | 33 | 102 | 2912 |
Robert D. Bullard | 33 | 92 | 7305 |
Stefan Boettcher | 33 | 194 | 9750 |