Institution
Commissariat à l'énergie atomique et aux énergies alternatives
About: Commissariat à l'énergie atomique et aux énergies alternatives is a based out in . It is known for research contribution in the topics: Layer (electronics) & Signal. The organization has 9958 authors who have published 9212 publications receiving 132235 citations.
Topics: Layer (electronics), Signal, Substrate (printing), Electrode, Transistor
Papers published on a yearly basis
Papers
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TL;DR: A modeled absolute chronology of the human and cave bear occupations of the Chauvet-Pont d'Arc Cave is derived and shows that there were two distinct periods of human activity in the cave, one from 37 to 33,500 y ago, and the other from 31 to 28,000 y ago.
Abstract: Radiocarbon dates for the ancient drawings in the Chauvet-Pont d’Arc Cave revealed ages much older than expected. These early ages and nature of this Paleolithic art make this United Nations Educational, Scientific and Cultural Organization (UNESCO) site indisputably unique. A large, multidisciplinary dating program has recently mapped the anthropological evolution associated with the cave. More than 350 dates (by 14C, U-Th, TL and 36Cl) were obtained over the last 15 y. They include 259 radiocarbon dates, mainly related to the rock art and human activity in the cave. We present here more than 80 previously unpublished dates. All of the dates were integrated into a high-precision Bayesian model based on archaeological evidence to securely reconstruct the complete history of the Chauvet-Pont d’Arc Cave on an absolute timescale. It shows that there were two distinct periods of human activity in the cave, one from 37 to 33,500 y ago, and the other from 31 to 28,000 y ago. Cave bears also took refuge in the cave until 33,000 y ago.
79 citations
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TL;DR: In this article, a search for supersymmetry involving the pair production of gluinos decaying via third-generation squarks into the lightest neutralino ((chi) over tilde (0)(1)) is reported.
Abstract: A search for supersymmetry involving the pair production of gluinos decaying via third-generation squarks into the lightest neutralino ((chi) over tilde (0)(1)) is reported. It uses LHC proton-prot ...
79 citations
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TL;DR: In this paper, the stability domains and the possible uptake of small amounts of magnesium by C-S-H or, reversely, the uptake of a small amount of calcium by magnesium silicate hydrate were investigated.
79 citations
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TL;DR: The reconstructed hadrons are used to classify the decay mode and to calculate the visible four-momentum of reconstructed tau candidates, significantly improving the resolution with respect to the calibration in the existing tau reconstruction.
Abstract: This paper presents a new method of reconstructing the individual charged and neutral hadrons in tau decays with the ATLAS detector. The reconstructed hadrons are used to classify the decay mode and to calculate the visible four-momentum of reconstructed tau candidates, significantly improving the resolution with respect to the calibration in the existing tau reconstruction. The performance of the reconstruction algorithm is optimised and evaluated using simulation and validated using samples of [Formula: see text] and [Formula: see text]+jets events selected from proton-proton collisions at a centre-of-mass energy [Formula: see text], corresponding to an integrated luminosity of 5 [Formula: see text].
78 citations
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TL;DR: This study presents the first atomic resolution structural characterization of a client protein bound to each of the three nucleotide states of DnaK and establishes that the large structural changes in DNAK and the associated energy that accompanies ATP binding and hydrolysis do not affect the overall conformation of the bound substrate protein.
Abstract: The 70 kDa heat shock protein (Hsp70) chaperone system is ubiquitous, highly conserved, and involved in a myriad of diverse cellular processes. Its function relies on nucleotide-dependent interactions with client proteins, yet the structural features of folding-competent substrates in their Hsp70-bound state remain poorly understood. Here we use NMR spectroscopy to study the human telomere repeat binding factor 1 (hTRF1) in complex with Escherichia coli Hsp70 (DnaK). In the complex, hTRF1 is globally unfolded with up to 40% helical secondary structure in regions distal to the binding site. Very similar conformational ensembles are observed for hTRF1 bound to ATP-, ADP- and nucleotide-free DnaK. The patterns in substrate helicity mirror those found in the unfolded state in the absence of denaturants except near the site of chaperone binding, demonstrating that DnaK-bound hTRF1 retains its intrinsic structural preferences. To our knowledge, our study presents the first atomic resolution structural characterization of a client protein bound to each of the three nucleotide states of DnaK and establishes that the large structural changes in DnaK and the associated energy that accompanies ATP binding and hydrolysis do not affect the overall conformation of the bound substrate protein.
78 citations
Authors
Showing all 9958 results
Name | H-index | Papers | Citations |
---|---|---|---|
Philippe Ciais | 149 | 965 | 114503 |
Stanislas Dehaene | 149 | 456 | 86539 |
W. Kozanecki | 138 | 1498 | 99758 |
Christophe Royon | 134 | 1453 | 90249 |
Jean-Luc Starck | 133 | 657 | 76224 |
Lucie Gauthier | 132 | 679 | 64794 |
Eric Lancon | 131 | 1084 | 84629 |
Ahmimed Ouraou | 131 | 1075 | 81695 |
Jean-Francois Laporte | 129 | 910 | 77899 |
Bruno Mansoulie | 129 | 923 | 79222 |
Maarten Boonekamp | 129 | 1005 | 79425 |
Laurent Chevalier | 129 | 982 | 80840 |
Nathalie Besson | 129 | 954 | 78653 |
Claude Guyot | 129 | 920 | 77544 |
Rosy Nicolaidou | 128 | 948 | 76056 |