Mahatma Gandhi Memorial Medical College

About: Mahatma Gandhi Memorial Medical College is a education organization based out in Indore, Madhya Pradesh, India. It is known for research contribution in the topics: Dyslipidemia & Lipid profile. The organization has 210 authors who have published 123 publications receiving 1085 citations. The organization is also known as: MGM Medical College.

Small bowel obstruction due to subserosal endometriosis: an elusive condition -

Abstract: The bowel is involved in 3.8 to 37% of women with endometriosis, out of which nearly 1% present with signs of bowel obstruction to the surgeon. This report describes a case of acute small bowel obstruction in a 23 years old woman. The patient gave a history of intermittent episodes of pain abdomen and abdominal distension for the past 1 year with significant loss of weight. The menstrual cycles were normal. Although there was no history of Tuberculosis, a positive history of contact was present. The clinical and biochemical picture was suggestive of peritonitis. CECT of the abdomen revealed a long segment distal ileal stricture. With a provisional diagnosis of Tubercular Ileo-Caecal stricture perforation, a midline exploratory laparotomy was performed. The procedure consisted of right limited hemicolectomy and primary ileo-ascending anastomosis with a proximal loop ileostomy. Ileostomy was done to allow the healing of distal anastomosis and closure was done after 4 weeks. Histopathology of the resected segment of ileum revealed subserosal endometriosis. Postoperatively, the patient was not given any hormonal therapy and recovery has been uneventful over the past 1 year of follow up.

Clinicopathologic study of large abdominal masses in gynaecological practice and their outcome

Abstract: Background: In female reproductive tract the differential diagnosis of pelvic mass is quite variable because abnormality may arise from gynaecological or non-gynaecological origin. The aim of the present study is to find out the causes why these patients come with large abdominal masses, to find out the risk factors and to do proper management. Methods: This study is a retrospective study of all cases of large abdominal mass All the patient coming with palpable abdominal and pelvic adnexal mass in the gynaecologic OPD were included in the study. Study population included women of all ages and the relevant population of women with treatment for fibroids and ovarian mass. The data was analysed retrospectively and the results were computed accordingly. Results: Incidence of large ovarian mass was found out to be 2.82% and of large fibroid was 2.31%. Our study showed the peak incidence of ovarian tumors in age group more than 40 years. 90.5% of patients were illiterate and only 10 patients were literate. In the study only 8.57% patients had addiction to some drug and all were tobacco chewer. The incidence of benign tumor was 83.33% (commonest being ovarian tumours) and that of malignant tumors is 16.66%. Conclusions: Ultrasound is effective in detecting the abdominal mass, size and type of abdominal mass, so that early diagnosis can be done and treatment can be given as soon as possible. Apart from already established risk factors, obesity and uterine fibroid have an important association.

Effects and association of pro-oxidants with magnesium in patients with diabetic nephropathy.

Abstract: Diabetic nephropathy (DN) is the most common microvascular complication observed in patients with type-2 diabetes mellitus. Furthermore, magnesium (Mg) deficiency is a common problem in diabetic patients. In this study, we estimated the levels of Mg, which is an important trace element and pro-oxidant marker, and then evaluated the association between serum Mg and pro-oxidants in patients with DN. In the present study, 200 patients were enrolled and were divided into two groups. The control and DN groups consisted of 100 healthy individuals and 100 patients with DN, respectively. Serum Mg, total anti-oxidant capacity (TAC), and superoxide dismutase (SOD) levels were estimated using the Calmagite, Koracevic, and Marklund and Marklund methods, respectively. Glutathione (GSH) and malondialdehyde (MDA) levels were estimated using the Tietze F and Jean CD method, respectively. Mg levels were found to be significantly decreased in the DN group in comparison to the control group. Anti-oxidant markers were statistically significantly reduced (P <0.001), whereas MDA levels were statistically significantly elevated (P <0.001) in the DN group compared to the control group. There was a significant positive association of Mg with TAC, SOD, and GSH. A statistically significant negative association of Mg with MDA (r = -0.302, P <0.001, n = 100) was also observed. An apparent relationship was observed between hypomagnesemia and oxidative stress in patients with DN. Lower levels of Mg and oxidative stress were also strongly linked.