Noida Institute of Engineering and Technology

About: Noida Institute of Engineering and Technology is a based out in . It is known for research contribution in the topics: Ultimate tensile strength & Microstrip. The organization has 248 authors who have published 369 publications receiving 2616 citations.

Fabrication and characterization of A359/Al2O3 metal matrix composite using electromagnetic stir casting method

Abstract: A composite material is a material consisting of two or more physically and chemically distinct phases. The composite has superior characteristics than those individual components. Usually the reinforcing component is distributed in the continuous or matrix component. When the matrix is a metal, the composite is termed a metal matrix composite (MMC). In MMCs, the reinforcement usually takes the form of particles, whiskers, short fibers, or continuous fibers. An MMC is a composite material with at least two constituent parts, one being a metal. The other material may be a different metal or another material, such as a ceramic or organic compound. Recently, aluminum and its alloy based cast MMCs have gained lot of popularity in all the emerging fields of engineering and technology owing to their superior strength, lower creep rate, better fatigue resistance, lower coefficients of thermal expansion as compared to monolithic materials. The desired properties of the cast MMCs are influenced by the solidification behavior of the cast MMCs. The present paper aimed to investigate the best possible predicted results and to carry out the experimental set up of electromagnetic stir casting process in composite materials. The present paper also shows significant effect of the mechanical properties such as hardness and tensile strength, and analyzes the microstructure of A359/Al2O3.

Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches.

Abstract: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel corona virus that causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the nations with high mortality rate even as very little is known to contain the virus at present. In the current study, we report novel natural metabolites namely, ursolic acid, carvacrol and oleanolic acid as the potential inhibitors against main protease (Mpro) of COVID-19 by using integrated molecular modeling approaches. From a combination of molecular docking and molecular dynamic (MD) simulations, we found three ligands bound to protease during 50 ns of MD simulations. Furthermore, the molecular mechanic/generalized/Born/Poisson-Boltzmann surface area (MM/G/P/BSA) free energy calculations showed that these chemical molecules have stable and favourable energies causing strong binding with binding site of Mpro protein. All these three molecules, namely, ursolic acid, carvacrol and oleanolic acid, have passed the ADME (Absorption, Distribution, Metabolism, and Excretion) property as well as Lipinski's rule of five. The study provides a basic foundation and suggests that the three phytochemicals, viz. ursolic acid, carvacrol and oleanolic acid could serve as potential inhibitors in regulating the Mpro protein's function and controlling viral replication. Communicated by Ramaswamy H. Sarma.

Surface treatments of plant fibers and their effects on mechanical properties of fiber-reinforced composites: A review:

Abstract: The need of natural fiber-reinforced composites is increasing at very fast rate because of their ecofriendly production, decomposition, high specific strength, abundance, good physical and mechanic...