Institution
Ronald Reagan UCLA Medical Center
Healthcare•Los Angeles, California, United States•
About: Ronald Reagan UCLA Medical Center is a healthcare organization based out in Los Angeles, California, United States. It is known for research contribution in the topics: Heart failure & Population. The organization has 730 authors who have published 765 publications receiving 13728 citations. The organization is also known as: UCLA Medical Center & The Reagan.
Topics: Heart failure, Population, Medicine, Stroke, Ejection fraction
Papers published on a yearly basis
Papers
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TL;DR: Global HHF registries are reviewed to describe the patient characteristics, management, outcomes and their predictors, quality improvement initiatives, regional differences, and limitations of the available data and propose a roadmap for the design and conduct of future H HF registries.
1,604 citations
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University of Pennsylvania1, Boston University2, University of Maryland, Baltimore3, Arcadia University4, McMaster University5, Rush University Medical Center6, University of North Carolina at Chapel Hill7, University of Chicago8, University of Michigan9, Tufts Medical Center10, University of Toronto11, University of Arizona12, New York University13, University of Delaware14, University of California, Davis15, Ronald Reagan UCLA Medical Center16, Johns Hopkins University School of Medicine17, ECRI Institute18, Cedars-Sinai Medical Center19, American College of Rheumatology20, University of Minnesota21
TL;DR: An evidence‐based guideline for the comprehensive management of osteoarthritis (OA) is developed as a collaboration between the American College of Rheumatology and the Arthritis Foundation, updating the 2012 ACR recommendations for the management of hand, hip, and knee OA.
Abstract: Objective To develop an evidence-based guideline for the comprehensive management of osteoarthritis (OA) as a collaboration between the American College of Rheumatology (ACR) and the Arthritis Foundation, updating the 2012 ACR recommendations for the management of hand, hip, and knee OA. Methods We identified clinically relevant population, intervention, comparator, outcomes questions and critical outcomes in OA. A Literature Review Team performed a systematic literature review to summarize evidence supporting the benefits and harms of available educational, behavioral, psychosocial, physical, mind-body, and pharmacologic therapies for OA. Grading of Recommendations Assessment, Development and Evaluation methodology was used to rate the quality of the evidence. A Voting Panel, including rheumatologists, an internist, physical and occupational therapists, and patients, achieved consensus on the recommendations. Results Based on the available evidence, either strong or conditional recommendations were made for or against the approaches evaluated. Strong recommendations were made for exercise, weight loss in patients with knee and/or hip OA who are overweight or obese, self-efficacy and self-management programs, tai chi, cane use, hand orthoses for first carpometacarpal (CMC) joint OA, tibiofemoral bracing for tibiofemoral knee OA, topical nonsteroidal antiinflammatory drugs (NSAIDs) for knee OA, oral NSAIDs, and intraarticular glucocorticoid injections for knee OA. Conditional recommendations were made for balance exercises, yoga, cognitive behavioral therapy, kinesiotaping for first CMC OA, orthoses for hand joints other than the first CMC joint, patellofemoral bracing for patellofemoral knee OA, acupuncture, thermal modalities, radiofrequency ablation for knee OA, topical NSAIDs, intraarticular steroid injections and chondroitin sulfate for hand OA, topical capsaicin for knee OA, acetaminophen, duloxetine, and tramadol. Conclusion This guideline provides direction for clinicians and patients making treatment decisions for the management of OA. Clinicians and patients should engage in shared decision-making that accounts for patients' values, preferences, and comorbidities. These recommendations should not be used to limit or deny access to therapies.
989 citations
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TL;DR: Management strategies that when properly implemented may help reduce HF rehospitalizations and include adopting a mechanistic approach to cardiac abnormalities, treating noncardiac comorbidities, increasing utilization of evidence-based therapies, and improving care transitions, monitoring, and disease management are highlighted.
617 citations
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TL;DR: PEGylation or covalent attachment of poly(ethylene glycol) improves the pharmacokinetic properties of protein drugs, resulting in improved patient quality of life and in vivo circulation lifetimes and dosages.
584 citations
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Harvard University1, Beth Israel Deaconess Medical Center2, Fudan University Shanghai Medical College3, Shanghai Jiao Tong University4, Peking Union Medical College5, Guangdong General Hospital6, Fourth Military Medical University7, Central University of Finance and Economics8, Huazhong University of Science and Technology9, University of California, Berkeley10, King's College London11, All India Institute of Medical Sciences12, Amrita Institute of Medical Sciences and Research Centre13, Nizam's Institute of Medical Sciences14, Ronald Reagan UCLA Medical Center15, National Research University – Higher School of Economics16, The Breast Cancer Research Foundation17
TL;DR: The overall state of health and cancer control in each country is described and additional specific issues for consideration are described: for China, access to care, contamination of the environment, and cancer fatalism and traditional medicine; for India, affordability of care, provision of adequate health personnel, and sociocultural barriers to cancer control.
Abstract: Summary Cancer is one of the major non-communicable diseases posing a threat to world health. Unfortunately, improvements in socioeconomic conditions are usually associated with increased cancer incidence. In this Commission, we focus on China, India, and Russia, which share rapidly rising cancer incidence and have cancer mortality rates that are nearly twice as high as in the UK or the USA, vast geographies, growing economies, ageing populations, increasingly westernised lifestyles, relatively disenfranchised subpopulations, serious contamination of the environment, and uncontrolled cancer-causing communicable infections. We describe the overall state of health and cancer control in each country and additional specific issues for consideration: for China, access to care, contamination of the environment, and cancer fatalism and traditional medicine; for India, affordability of care, provision of adequate health personnel, and sociocultural barriers to cancer control; and for Russia, monitoring of the burden of cancer, societal attitudes towards cancer prevention, effects of inequitable treatment and access to medicine, and a need for improved international engagement.
400 citations
Authors
Showing all 742 results
Name | H-index | Papers | Citations |
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Gregg C. Fonarow | 161 | 1676 | 126516 |
Deepak L. Bhatt | 149 | 1973 | 114652 |
Jeffrey L. Saver | 116 | 677 | 59170 |
Michael C. Fishbein | 116 | 701 | 50402 |
Ronald W. Busuttil | 109 | 819 | 46281 |
Harry V. Vinters | 108 | 566 | 51351 |
Timothy F. Cloughesy | 106 | 559 | 44370 |
Lee H. Schwamm | 101 | 594 | 44559 |
Adrian F. Hernandez | 100 | 849 | 41095 |
Eric E. Smith | 100 | 544 | 33968 |
Larry B. Goldstein | 85 | 434 | 36840 |
Gary Duckwiler | 80 | 308 | 25690 |
David S Liebeskind | 79 | 773 | 29849 |
Allan J. Pantuck | 74 | 362 | 21728 |
Jiaoti Huang | 73 | 327 | 19148 |