Wisconsin Alumni Research Foundation

About: Wisconsin Alumni Research Foundation is a nonprofit organization based out in Madison, Wisconsin, United States. It is known for research contribution in the topics: Signal & Layer (electronics). The organization has 4209 authors who have published 3523 publications receiving 61017 citations.

Detecting compounds with liquid crystals

Abstract: A device for detecting a compound in a sample includes a substrate and a self-assembled monolayer. The substrate includes a support with a metallized top surface, and the self-assembled monolayer includes an alkanethiol attached to the metallized top surface of the substrate and having a functional group that reversibly or irreversibly interacts with the compound. A liquid crystal is disposed on the self-assembled monolayer opposite the side of the self-assembled monolayer attached to the metallized top surface of the substrate. The liquid crystal includes a moiety that interacts with the functional group of the alkanethiol. When the compound is present in a sample that that contacts the self-assembled monolayer, the orientation of the liquid crystal is altered.

Horizontal gel electrophoresis apparatus

Abstract: A horizontal electrophoresis assembly is described which is designed to utilize very thin gels of polyacrylamide. The assembly allows for water cooling of the gel during electrophoresis so that higher voltages can be applied to the gel without polymer degradation. The gel mold is made from a set of glass plates which are clamped into place defining a gel mold between them. In one embodiment, the site of field introduction is separated from the site of sample introduction so that the electric field is generally linear at the region of sample introduction.

Method and apparatus for measuring blood iodine concentration

Abstract: A method and apparatus for measuring blood iodine concentration draws a continuous specimen of blood containing iodine from the left ventricle of the heart and exposes that specimen to a source of X-rays. The attentuated level of X-rays passing through the specimen is compared with the unobstructed level of X-rays to determine the concentration of iodine in the blood. The measurement is then corrected to account for the effects of dispersion caused by the travel of the specimen from the heart to the measurement zone.

Treatment of blood with oleaginous substance

Abstract: METHOD AND MEANS FOR THE TREATMENT OF BLOOD AND OTHER BODY FLUIDS TO ADD OR SUBTRACT INGREDIENTS WITH RESPECT TO THE BLOOD BY PASSING THE BLOOD IN LIQUID-LIQUID CONTACT WITH AN IMMISCIBLE OLEAGINOUS MATERIAL.

Method of error reduction in nucleic acid populations

Abstract: A method is disclosed for the direct synthesis of double stranded DNA molecules of a variety of sizes and with any desired sequence. The DNA molecule to be synthesis is logically broken up into smaller overlapping DNA segments. A maskless microarray synthesizer is used to make a DNA microarray on a substrate in which each element or feature of the array is populated by DNA of a one of the overlapping DNA segments. The complement of each segment is also made in the microarray. The DNA segments are released from the substrate and held under conditions favoring hybridization of DNA, under which conditions the segments will hybridize to form duplexes. The duplexes are then separated using a DNA binding agent which binds to improperly formed DNA helixes to remove errors from the set of DNA molecules. The segments can then be hybridized to each other to assemble the larger target DNA sequence.