Showing papers by "Wisconsin Alumni Research Foundation published in 2015"

High throughput semiconductor deposition system

Abstract: A reactor for growing or depositing semiconductor films or devices. The reactor may be designed for inline production of III-V materials grown by hydride vapor phase epitaxy (HVPE). The operating principles of the HVPE reactor can be used to provide a completely or partially inline reactor for many different materials. An exemplary design of the reactor is shown in the attached drawings. In some instances, all or many of the pieces of the reactor formed of quartz, such as welded quartz tubing, while other reactors are made from metal with appropriate corrosion resistant coatings such as quartz or other materials, e.g., corrosion resistant material, or stainless steel tubing or pipes may be used with a corrosion resistant material useful with HVPE-type reactants and gases. Using HVPE in the reactor allows use of lower-cost precursors at higher deposition rates such as in the range of 1 to 5 μm/minute.

Computer with Hybrid Von-Neumann/Dataflow Execution Architecture

Abstract: A dataflow computer processor is teamed with a general computer processor so that program portions of an application program particularly suited to dataflow execution may be transferred to the dataflow processor during portions of the execution of the application program by the general computer processor. During this time the general computer processor may be placed in partial shutdown for energy conservation.

High mass accuracy filtering for improved spectral matching of high-resolution gas chromatography-mass spectrometry data against unit-resolution reference databases

Abstract: The invention provides methods, systems and algorithms for identifying high- resolution mass spectra. In some embodiments, an analyte is ionized and analyzed using high-resolution mass spectrometry (MS) at high mass accuracy (such as ≤ 75 ppm or ≤ 30 ppm) and the obtained mass spectra are matched with one or more prospective candidate molecules or chemical formulas. The invention provide, for example, methods and systems wherein the possible fragments that can be generated from the candidate molecules or chemical formulas are determined as well as the masses of each of these fragments. The invention provide, for example, methods and systems wherein the high-resolution mass spectra are then compared with the calculated fragment masses for each of the candidate molecules or chemical formula, and the portion of the high-resolution mass spectra that corresponds or can be explained by the calculated fragment masses is determined.

Self-loading microfluidic device and methods of use

Abstract: Microfluidic devices and methods for conducting chemical assays and biological assays using microfluidic devices are disclosed. The microfluidic devices do not require external connections, tethers, tubing, valves and actuators. The microfluidic devices are useful in methods for analyzing a wide variety of chemical and biological assays such as, for example, molecule-molecule interactions, enzyme-substrate interactions, molecule identification, minimum inhibitory concentrations, therapeutically effective amounts, and toxic amounts.

Solution growth of single-crystal perovskite structures

Abstract: A method for growing single-crystal perovskite structures comprises immersing a film of a metal precursor compound on a surface of a substrate, the metal precursor compound comprising a metal ion B, in a solution comprising a cation precursor compound, the cation precursor compound comprising a cation ion A and an anion X, at a concentration of the cation precursor compound, a growth time, and a growth temperature sufficient to dissolve the film to release the metal ion B to form a complex with the anion X and sufficient to induce recrystallization of the complex with the cation ion A to form a plurality of single-crystal perovskite structures composed of A, B and X The single-crystal perovskite structures, devices incorporating the same, and methods of using the devices are also provided

Constructs and methods for genome editing and genetic engineering of fungi and protists

Abstract: Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.

Cache Accessed Using Virtual Addresses

Abstract: A computer architecture provides a memory cache that is accessed not by physical addresses but by virtual addresses directly from running processes. Ambiguities that can result from multiple virtual addresses mapping to a single physical address are handled by dynamically tracking synonyms and connecting a limited number of virtual synonyms mapping to the same physical address to a single key virtual address that is used exclusively for cache access.

System And Method For Time-Resolved, Three-Dimensional Angiography With Flow Information

Abstract: A system and method are provided for generating time resolved series of angiographic volume data having flow information integrated therewith. The method includes generating a series of 3D time-resolved vascular volumes from time resolved x-ray projection data and calculating blood velocity in the vascular volumes x-ray projection data to determine a rate of change of calculated contrast material arrival time at positions along the vascular volumes. The method also includes displaying the 3D time-resolved vascular volumes with a graphical indication of blood velocity in the vascular volumes.

Hybrid heterostructure light emitting devices

Abstract: Light-emitting devices having a multiple quantum well (MQW) pin diode structure and methods of making and using the devices are provided. The devices are composed of multilayered semiconductor heterostructures. The devices include one or more interfacial layers of a material that allows current tunneling through lattice mismatched heterogeneous junctions at the interfaces between the intrinsic active region and the p-type and/or n-type doped charge injection layers.

Efficient memory management system for computers supporting virtual machines

Abstract: The translation of virtual guest addresses to host physical addresses in a virtualized computer system provides a compound page table that may simultaneously support nested-paging and shadow-paging for different memory regions. Memory regions with stable address mapping, for example, holding program code, may be treated using shadow-paging while memory regions with dynamic address mapping, for example, variable storage, may be treated using nested-paging thereby obtaining the benefits of both techniques.

Electrochemical and photoelectrochemical oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid and 2,5-diformylfuran

Abstract: Electrochemical and photoelectrochemical cells for the oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid and/or 2,5-diformylfuran are provided. Also provided are methods of using the cells to carry out the electrochemical and photoelectrochemical oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid and/or 2,5-diformylfuran.

Charge Transfer Mediator Based Systems for Electrocatalytic Oxygen Reduction

Abstract: Disclosed are systems for the electrocatalytic reduction of oxygen, having redox mediator/redox catalyst pairs and an electrolyte solution in contact with an electrode. The redox mediator is included in the electrolyte solution, and the redox catalyst may be included in the electrolyte solution, or alternatively, may be in contact with the electrolyte solution. In one form a cobalt redox catalyst is used with a quinone redox mediator. In another form a nitrogen oxide redox catalyst is used with a nitroxyl type redox mediator. The systems can be used in electrochemical cells wherein neither the anode nor the cathode comprise an expensive metal such as platinum.

Permanent magnet synchronous motor

Abstract: A permanent magnet synchronous motor includes a stator, a rotor rotatable relative to the stator, and a magnetic structure with a low coercive force magnet and a high coercive force magnet that are arranged magnetically in series with respect to each other to define a pole-pair of the permanent magnet synchronous motor. A magnetization level of the low coercive force magnet is changeable by a stator current pulse such that a stator magnetomotive force at a rated current is equal to or larger than a product of a magnetic field strength for fully magnetizing the low coercive force magnet and a thickness of the low coercive force magnet.

Medical Imaging System Providing Disease Prognosis

Abstract: A medical imaging system that processes input data (imaging and/or non imaging) having high dimensionality and few samples to learn from, by using multiple ranks of machine learning modules each dealing with a separate portion of the clinical data. The outputs of the individual machine learning modules are the combined to provide a result reflective of the complete image data set.

Microphase separation of block copolymer bottlebrushes

Abstract: Provided herein are microphase-separated materials including a plurality of block copolymers tethered together at their A-B junction points. The tethered-together block copolymers, referred to as a block copolymer bottlebrush, provide microphase-separated materials having smaller domain spacing than previously achievable using block copolymer systems.

System and method for determining dynamic physiological information from four-dimensional angiographic data

Abstract: A system and method are provided for generating time resolved series of angiographic volume data having flow information. The system and method are configured to receive angiographic volume data acquired from a subject having received a dose of a contrast agent using an imaging system and process the angiographic volume data to generate angiographic volume images. The angiographic volume data is processed to derive flow information by determining a distance between two points along a vessel in the angiographic volume images and determining a phase at each of the two points along the vessel in the angiographic volume images. A flow direction or a velocity of flow within the vessel is determined using the distance between the two points along the vessel and the phase at each of the two points along the vessel.

Peg-Style Electrostatic Rotating Machine

Abstract: An electrostatic rotating electrical machine employs interdigitated axial pegs on opposed rotor and stator plates, the pegs immersed in a high dielectric constant fluid. Peg shape, length and positioning may be varied to tailor a changing aspect profile to a desired power source.

Alpha/beta-peptide mimics of z-domain peptides

Abstract: Described are α/β-peptide mimics of Z-domain scaffold peptides, methods of making them, and methods of using them. The α/β-peptide mimics include β-amino acid residues and, optionally, disulfide bonds to stabilize the conformation of the mimics. The compounds may be truncated as compared to conventional Z-domain scaffold peptides and are resistant to proteolytic degradation due to the presence of β-amino acid residues. The mimics can be made so as to bind selectively to a desired target.

Continuous, floating evaporative assembly of aligned carbon nanotubes

Abstract: High density films of semiconducting single-walled carbon nanotubes having a high degree of nanotube alignment are provided. Also provided are methods of making the films and field effect transistors (FETs) that incorporate the films as conducting channel materials. The single-walled carbon nanotubes are deposited from a thin layer of organic solvent containing solubilized single-walled carbon nanotubes that is continuously supplied to the surface of an aqueous medium, inducing evaporative self-assembly upon contacting a solid substrate.

Three-dimension printer with mechanically scanned cathode-comb

Abstract: A 3-D printer scalable to large sizes employs a combination of mechanical and electrical scanning of a linear array of electron beams that operate to melt material of a powder bed. A housing holding the electron beam sources may be maintained at a high vacuum and positioned close to a print surface to minimize electron travel in a softer vacuum surrounding a print bed.

Epitaxial growth of high quality vanadium dioxide films with template engineering

Abstract: Layered oxide structures comprising an overlayer of high quality VO2 and methods of fabricating the layered oxide structures are provided Also provided are high-speed switches comprising the layered structures and methods of operating the high-speed switches The layered oxide structures include high quality VO2 epitaxial films on isostructural SnO2 growth templates

Hydrogel compositions for use in promoting tubulogenesis

Abstract: Hydrogel Compositions and methods of using hydrogel compositions are disclosed. Advantageously, the hydrogel compositions offer the ability to rapidly screen substrate components for influencing cell attachment, spreading, proliferation, migration, and differentiation. In particularly suitable embodiments, the hydrogel compositions of the present disclosure may be used to promote tubulogenesis of endothelial cells.

Derivation of human microglia from pluripotent stem cells

Abstract: The present invention relates to methods for deriving human hematopoietic progenitors, primitive macrophages, and microglial cells from human pluripotent stem cells. In particular, provided herein are highly efficient and reproducible methods of obtaining human primitive macrophages and microglia from human pluripotent stem cells, where the primitive macrophages and microglia can be suitable for clinically relevant therapeutic applications.

Recombinant yeast having enhanced xylose fermentation capabilities and methods of use

Abstract: The present invention relates to the production of biofuels and chemical feedstocks. The present invention provides recombinant yeast having enhanced xylose fermentation capabilities. Methods of using such recombinant yeast for improved biofuel and chemical feedstock production are also provided.

Converter control using reduced link capacitor

Abstract: A controller selects a first switch vector based on a current, voltage, or power of a multi-phase load or power source. The first switch vector identifies a first state for each of a plurality of half-bridges of a converter as on or as off during a first interval. A second switch vector is selected based on the current, voltage, or power of the multi-phase load or power source. The second switch vector identifies a second state for each of the half-bridges as on or as off during a second interval. The first interval is computed based on the selected first switch vector. The second interval is computed based on the selected second switch vector. Each of the plurality of half-bridges is controlled as on or as off during the first interval based on the selected first switch vector and during the second interval based on the selected second switch vector.

Location-Aware Communication System Using Visible Light Transmission

Abstract: A visible light communication system identifies the location of a mobile device using light intensities corrected by mobile device orientation. This location can be used to generate a dynamic cluster of visible light transmitters about the mobile device providing improved “handoff” between transmitters and reduced shadowing.

Interior permanent magnet machine with axially varying permanent magnet size

Abstract: A rotor includes pole portions, a first permanent magnet, a second permanent magnet, and a third permanent magnet. Each pole portion includes a center, a back, and a front rotor core portion. A first slot is embedded in the center rotor core portion. A second slot is embedded in the back rotor core portion. A third slot is embedded in the front rotor core portion. The center rotor core portion is mounted axially between the front rotor core portion and the back rotor core portion. The permanent magnets are mounted, respectively, in the slots of each pole portion. A maximum length of the first permanent magnet is greater than twice a maximum length of the second permanent magnet. The maximum length of the second permanent magnet is equal to a maximum length of the third permanent magnet. The permanent magnets are aligned relative to a pole axis of each pole portion.

Methods and compositions for determining bovine ovulation rate

Abstract: Described herein are methods and compositions for modulating bovine birth rate by following a breeding scheme based on the presence of the trio haplotype, which is strongly linked to the propensity to give birth to multiple calves in one event.

Hybrid tandem solar cells with improved tunnel junction structures

Abstract: Tandem solar cells comprising two or more solar cells connected in a solar cell stack via pn diode tunnel junctions and methods for fabricating the tandem solar cells using epitaxial lift off and transfer printing are provided. The tandem solar cells have improved tunnel junction structures comprising a current tunneling layer integrated between the p and n layers of the pn diode tunnel junction that connects the solar cells.

Epsilon negative loaded traveling wave tube

Abstract: A slow wave structure of a traveling wave tube is provided. The slow wave structure includes an input port, an output port, a first material, and a second material. The second material is mounted in the first material at periodic intervals in a direction of propagation of a radio frequency signal between the input port and the output port. The second material has a real part of permittivity that is negative and a real part of permeability that is positive at an operational frequency of the radio frequency signal.