Wisconsin Alumni Research Foundation

About: Wisconsin Alumni Research Foundation is a nonprofit organization based out in Madison, Wisconsin, United States. It is known for research contribution in the topics: Signal & Layer (electronics). The organization has 4209 authors who have published 3523 publications receiving 61017 citations.

Methods and apparata for precisely dispensing microvolumes of fluids

Abstract: Devices and methods for depositing fluids on substrates in patterns of spots, lines, or other features use a nozzle, which is preferably configured similarly to a micropipette, having a piezoelectric crystal or other ultrasonic actuator coupled to one of its sides. The nozzle may be charged via capillary action by dipping it into a well containing the fluid to be deposited, and may then be positioned over a desired area of a substrate, at which point activation of the ultrasonic actuator at ultrasonic frequencies will eject the fluid onto the substrate. The needle may subsequently be dipped into a well of rinsing fluid for cleaning. Spots or lines on the order of 5 micrometers width may be generated, making the invention particularly suitable for use in biological applications such as microarray production and in microelectronics applications such as the printing of organic circuitry.

Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same

Abstract: Disclosed is a device, such as a cardiovascular stent, autologous venous/arterial graft, prosthetic venous/arterial graft, vascular catheter, or vascular shunt, for stenting a blood vessel. The device has coated thereon, adsorbed thereto, impregnated therein, or covalently or ionically bonded thereto an amount of a protein tyrosine kinase inhibitor. The protein tyrosine kinase inhibitor proliferation of vascular smooth muscle cells in an area within a blood vessel immediately adjacent to and/or proximal to the device, while simultaneously not inhibiting the proliferation of vascular intimal cells. A corresponding method of using the device to stent blood vessels is also disclosed.

Taxol composition for use as organ preservation and cardioplegic agents

Abstract: A composition containing taxol for the ex vivo preservation or perfusion of organs for implantation in a subject requiring such implantation, or for cardioplegia, is disclosed.

System and method for high-frequency amplifier

Abstract: A system and method for operating an amplifier system is provided. The amplifier system includes an input providing a direct coupling configured to receive a high-frequency input signal having a frequency in at least one of a radiofrequency (RF) and microwave range. The amplifier system also includes an amplifier including a dielectric material separating at least two superconducting layers forming an amplifier loop configured to receive the high-frequency input signal and deliver an amplified signal. The amplifier system includes an output providing a direct coupling configured to deliver the amplified signal.

Method and apparatus for wavelength conversion and switching

Abstract: A two-dimensional second order nonlinear lattice formed in a lattice body is utilized for performing a one-step optical carrier wavelength interchange between pairs of input optical signals. The lattice body includes sensitized regions arranged in a two-dimensional array in a matrix material with the sensitized regions differing from the matrix material in the sign of the second order susceptibility. When an optical pump signal is coupled to the lattice body at a frequency corresponding to the sum of the frequencies of the two input signals, nonlinear interactions in the lattice body produce wavelength interchange between the input signals, resulting in angularly deflected optical signals exiting the lattice body in which the signal information on the input signals is interchanged between the carrier frequencies of the two input signals. The apparatus can be utilized to provide switching of optical signals and wavelength interchange for applications such as in wavelength division multiplexed communication systems.