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Showing papers in "American Heart Journal in 1990"


Journal ArticleDOI
TL;DR: There is a residual effect for glucose intolerance after all the standard risk factors and fibrinogen have been taken into account, which suggests a thrombogenic explanation for the unique diabetic effect.

372 citations


Journal ArticleDOI
TL;DR: It is suggested that CAD among persons who are predicted to be at low risk by standard risk factors may have a substantial genetic component and that the risk associated with parental history may not be reduced by modification of these factors.

351 citations


Journal ArticleDOI
TL;DR: The results of this study demonstrate that mass, volume, and functional measurements are reproducible in morphologically abnormal ventricles.

310 citations


Journal ArticleDOI
TL;DR: Large, protrusive plaques in the aortic arch and descending aorta, which have mobile projections that move freely with the blood flow are shown; these lesions could be responsible for embolic syndromes, especially after catheter manipulation in theAorta.

296 citations


Journal ArticleDOI
TL;DR: A new angiographic score that assesses the extent of coronary disease is simple to perform and correlates better with age and lipoprotein risk factors than conventional scores do.

277 citations


Journal ArticleDOI
TL;DR: Of the six common methods evaluated, the aortic annular leading edge method measures stroke volume with the best accuracy and is most suitable for clinical application.

259 citations


Journal ArticleDOI
TL;DR: A general introduction to the basics of the mathematics, applications to cardiology, and a brief review of the new tools needed to use the concepts of nonlinear mathematics are given.

253 citations


Journal ArticleDOI
TL;DR: It is suggested that idiopathic VF represents an underestimated cause of sudden cardiac death in ostensibly healthy patients and an international registry of patients with documented VF is warranted.

229 citations


Journal ArticleDOI
TL;DR: Intravascular imaging with high-frequency ultrasound is an accurate method for measuring microanatomic arterial dimensions and the extent of atheromatous involvement of the arterial wall and could represent an important adjunct to traditional angiographic techniques for assessing the severity of atherosclerosis.

206 citations


Journal ArticleDOI
TL;DR: The plasma ir-ET level is increased in the acute phase of AMI, and a pathophysiologic state characterized by cardiac dysfunction, an activated coagulation system, and platelet hyperactivity may be associated with this increase.

203 citations


Journal ArticleDOI
TL;DR: It is indicated that permanent, apically-initiated VVI pacing ultimately predisposes to adverse cellular changes associated with hemodynamic and electrophysiologic deterioration in the intact, developing immature canine heart.

Journal ArticleDOI
TL;DR: The results show that the magnitude of time required to evaluate, transport, and initiate thrombolytic therapy will preclude initiation of treatment to most patients within the first hour of symptoms.

Journal ArticleDOI
TL;DR: Although PTCA in chronic dialysis patients is technically feasible and provides relief of angina, aggressive restenosis limits the long-term benefit andCoronary bypass surgery may be the preferred therapy for this unique patient group.

Journal ArticleDOI
TL;DR: While the crude long-term survival rate for patients with AF was poorer than that of patients without AF for the combined as well as for individual study periods, similar to the in-hospital findings the independent effect of AF on long- term prognosis was not upheld after use of a multivariate analysis.

Journal ArticleDOI
TL;DR: These findings permit the following conclusions on cardiac changes induced by high-performance sports and high levels of training to be drawn.

Journal ArticleDOI
TL;DR: A normal exercise echocardiogram in a patient with good exercise capacity was predictive of an excellent prognosis, even in those who had abnormal exercise ECGs, and myocardial infarction and death were rare events,Even in patients with decreased exercise capacity.


Journal ArticleDOI
TL;DR: Some of the risk factors associated with coronary heart disease are examined, notably, advancing age, hypertension, left ventricular hypertrophy, smoking, elevated serum cholesterol, and reduced high-density lipoprotein, all of which have been investigated by the Framingham Heart Study.

Journal ArticleDOI
TL;DR: In cases in which no pathologic condition was identified, transesophageal echocardiography was useful in ruling out intracardiac shunt, in assessing left ventricular function, and in excluding significant valvular pathologic conditions.

Journal ArticleDOI
TL;DR: Findings suggest that a history of prior angina is not necessarily associated with an unfavorable short-term prognosis after reperfusion therapy, and may be related to the beneficial effects of collateral vessels, myocardial preconditioning, or differences in the native fibrinolytic system.

Journal ArticleDOI
TL;DR: The noncardiac mode of death in a large percentage of the patients suggests that the bypass operation prolonged life to a degree sufficient for another condition to develop, and therapy after the operation must be directed toward prevention of progression of the atherosclerosis in the "new" coronary "arteries."

Journal ArticleDOI
TL;DR: Pericardial effusion may be a frequent manifestation in myxedema, an advanced severe stage, but a rare association of hypothyroidism, an early mild stage, because of the timeliness with which the latter condition is nowadays detected.

Journal ArticleDOI
TL;DR: Inter intravenous dipyridamole thallium scintigraphy is a useful noninvasive test for risk stratification of patients before peripheral vascular surgery and provides prognostic information as to the risk of a cardiac event in the 2-year period after the test.

Journal ArticleDOI
TL;DR: The prevalence of heart failure in Northwest London is 0.4%, a lower figure than that quoted for the United States, and the prognosis for patients admitted to the hospital is poor.

Journal ArticleDOI
TL;DR: Progress of aortic stenosis as assessed by Doppler echocardiography was examined, and patients reported an increase in symptoms from the first to third examination, and their rate of progression was significantly different from that of the rest of the population.

Journal ArticleDOI
TL;DR: Aerobic exercise training favorably alters plasma lipoprotein profiles and a minimum training intensity equal to 75% maximal heart rate is required to the increase HDL cholesterol level.

Journal ArticleDOI
TL;DR: It is concluded that visual estimates of lesion severity are consistently and significantly higher than quantitative measurements, and restenosis rates, using currently applied definitions, differ considerably depending on the method of analyzing lesions severity.

Journal ArticleDOI
TL;DR: The last decade has witnessed an enormous increase in the use and success of percutaneous transluminal coronary angioplasty and of how it relates to the pathophysiology of restenosis, and it is likely that the problem ofrestenosis will be improved, either through existing technology or by methods yet to be discovered.

Journal ArticleDOI
TL;DR: The results suggest that unsuspected coronary artery disease is common in this particular group of patients with diabetes mellitus, particularly in patients with concomitant hypertension and cigarette smoking.

Journal ArticleDOI
TL;DR: Radionuclide angiography in the diagnosis of congenital intrapericardial aneurysm of the left atria1 appendage and cross-sectional echocardiography.