Showing papers in "American Heart Journal in 2002"

TL;DR: Although the precise cause remains unclear, simultaneous multivessel coronary spasm at the epicardial artery or microvascular levels may contribute to the onset of tako-tsubo-like left ventricular dysfunction.

TL;DR: The data may support the rationale of randomized trials to verify the effects on mortality rate of ventricular resynchronization with multisite cardiac pacing in patients with CHF and LBBB.

TL;DR: The Heinz Nixdorf RECALL study will define appropriate methods for identifying high-risk subgroups in the general urban population who may derive the greatest benefit from preventive treatment.

TL;DR: Smoking cessation and hypertension control are important goals in the aim to reduce PAD and its associated impact on quality of life, functional decline, and risk for subsequent cardiovascular disease.

TL;DR: The accuracy of the coding of acute myocardial infarction and other cardiac diagnoses in the Canadian Institute of Health Information hospital discharge abstracts is generally accurately coded in Ontariohospital discharge abstract data.

TL;DR: Patients with severe MR or TR represent high-risk subsets of patients with LVSD and future study is warranted to determine whether pharmaceutical or surgical strategies to relieve MR and TR have a favorable impact on survival.

TL;DR: QRS prolongation is an independent predictor of both increased total mortality and sudden death in patients with heart failure and age, type of cardiomyopathy, and drug treatment group were not predictive of mortality.

TL;DR: This is a first attempt to define cutoff values on the basis of the European Society of Cardiology and American College of cardiology guidelines to provide increased consistency until assays improve to allow full implementation of the guidelines.

TL;DR: Quality of life is better with ICD therapy than with amiodarone therapy, and the beneficial quality-of-life effects from an ICD are not evident in patients who receive numerous shocks from their device.

TL;DR: In this article, the effects of exercise training on functional capacity in patients with heart failure were examined, and significant increases were observed in the exercise group for arm and leg strength compared with the control group.

TL;DR: The independent association of high diuretic doses with mortality suggests that diUREtic resistance should be considered an indicator of prognosis in patients with chronic CHF.

TL;DR: Dobutamine is associated with substantial proarrhythmic and chronotropic effects in patients with decompensated CHF, whereas nesiritide actually reduces ventricular ectopy or has a neutral effect, compared with dobutamine.

TL;DR: Data suggest that current management and aggressive risk factor modification are quite good in this particular group of very young patients with acute myocardial infarction, and overall the mortality rate is very low.

TL;DR: Elderly patients with HF are a heterogeneous group and appear to differ substantially from patients enrolled in clinical trials, and evidence-based guidance for treatment in the context of multiple comorbid conditions, poor renal function, HF with preserved left ventricular systolic function, and residence in long-term care facilities is urgently needed.

TL;DR: In patients with symptomatic AF, QOL improves after treatment, independent of the specific drug used for treatment, especially true for patients in whom treatment prevents AF recurrence.

TL;DR: C-reactive protein is a moderately strong marker of risk of CHD in this cohort of middle-aged adults, consistent with the role of inflammation in the pathogenesis of coronary heart disease events.

TL;DR: Policosanol as discussed by the authors is a mixture of higher primary aliphatic alcohols isolated from sugar cane wax, whose main component is octacosanol, which has been shown to lower cholesterol in animal models, healthy volunteers, and patients with type II hypercholesterolemia.

TL;DR: It is suggested that HDL-mediated increases in eNOS expression may contribute to the observed enhancement in vasorelaxation and thus support a previously unrecognized mechanism for the beneficial cardiovascular effects of HDL.

TL;DR: The results suggest that sex, age, smoking, hypertension, diabetes, and hypercholesterolemia may affect the symptoms of acute myocardial infarction.

TL;DR: ASA+BB is an underused therapy in patients with acute myocardial infarction who have underlying kidney disease who are more likely to be male, free of earlier cardiac disease, and recipients of thrombolysis.

TL;DR: In this article, B-Type natriuretic peptide (BNP) was used to diagnose and evaluate the severity of congestive heart failure (CHF) based on the New York Heart Association (NYHA) classification system.

TL;DR: It is suggested that fenoldopam mesylate is a promising prophylactic agent for RCN and that larger multicenter trials should be conducted to prove its efficacy.

TL;DR: Elderly patients are seen in a more advanced stage of HF, are less likely to receive evidence-based treatments, show more frequently preserved systolic function, and have a worse prognosis, Consequently, there is a need to develop more effective and targeted management strategies for this escalating health problem.

TL;DR: A rational and pragmatic risk stratification process with symptom-limited cardiopulmonary exercise testing in CHF should include both peak VO2 and VE/VCO2 slope, the latter index effectively predicting outcome in almost one fourth of patients with intermediate exercise capacity.

TL;DR: The data favor treating asymptomatic patients, if <40 years old at the time of diagnosis, with beta-adrenergic blockers, and the long-term treatment is aimed at reducing the QT-interval duration and preventing the torsades and sudden death.

TL;DR: Compared with atorvastatin, rosuVastatin produced greater reductions in LDL-C, which may offer advantages in LDL -C goal attainment over existing lipid-lowering therapies.

TL;DR: The pharmacokinetic and pharmacodynamic profiles after enoxaparin administration are consistent across a broad range of patients with ACS, and creatinine clearance emerged as the most influential factor on apparent clearance, area under the curve, and anti-Xa activity.

TL;DR: Bivalirudin with planned or provisional abcximab may be at least as safe and effective as low-dose heparin plus abciximab during percutaneous coronary intervention.

TL;DR: The association between the minK 38G allele and clinical atrial fibrillation is reported and suggest possible genetic control on the pathogenesis of atrialfibrillation.

TL;DR: Rosuvastatin reduced LDL-C levels more than pravastatin or simvastatin in patients with hypercholesterolemia in a 52-week dose-titration study.