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Showing papers in "American Journal of Hypertension in 1997"


Journal ArticleDOI
TL;DR: The relationship between the decline in nocturnal blood pressure and mortality was examined and was more pronounced for cardiovascular than for noncardiovascular mortality, and did not change after the data were adjusted for 24-h, daytime, and nighttime blood pressure levels.

433 citations


Journal ArticleDOI
TL;DR: Despite frequent interactions with the health care system, too many Canadians are still not well controlled or are unaware of their hypertension.

376 citations


Journal ArticleDOI
TL;DR: The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study is a double-blind, prospective, parallel group study designed to compare the effects of losartan with those of the beta-blocker atenolol on the reduction of cardiovascular morbidity and mortality in approximately 8,300 hypertensive patients.

349 citations



Journal ArticleDOI
TL;DR: It is suggested that a reduced intracellular magnesium concentration might be the missing link helping to explain the epidemiological association between NIDDM and hypertension.

298 citations


Journal ArticleDOI
TL;DR: The excess of hypertension among blacks has been recognized since early in this century and explains a substantial portion of the black health disadvantage, and no clear cross-population differences are yet apparent.

269 citations


Journal ArticleDOI
TL;DR: Drug choice, comorbidity, and health services utilization were significantly associated with AHT compliance and represent important considerations in the management of high blood pressure.

266 citations


Journal ArticleDOI
TL;DR: The relationship between mean blood pressure and leptin showed a significant positive correlation in all of the subjects, suggesting that leptin may be related to the pathophysiology of essential hypertension.

237 citations


Journal ArticleDOI
TL;DR: Pressure natriuresis in obesity may also be attributable to altered intrarenal forces caused by histologic changes in the renal medulla that may compress the loops of Henle and vasa recta, increase tubular sodium reabsorption, and activate the renin-angiotensin system.

226 citations


Journal ArticleDOI
TL;DR: Among hypertensive subjects, PRA level (without urine sodium), is independently and directly associated with the incidence of MI, and only renin, age, sex, smoking, LVH, and cholesterol were significantly related to MI occurrence.

192 citations


Journal ArticleDOI
TL;DR: The results indicated that the predictive power of home BP level for subsequent mortality was stronger than that of casual screening BP, and the reference value for hypertension is 137/84 mm Hg, and normotension is below 137mm Hg for home systolic BP and between 66 and 83 mm HG for home diastolic BP.

Journal ArticleDOI
TL;DR: It is demonstrated that sympathetic nerve hyperactivity appears to precede hyperinsulinemia and resultant BP elevation in a young, nonobese Japanese population.

Journal ArticleDOI
TL;DR: The results suggested the possible involvement of increased p-AGT in hypertension in obese patients, although this may be a secondary change to hypertension or obesity.


Journal ArticleDOI
TL;DR: The hypothesis that circulating levels of soluble cell adhesion molecules are elevated in older men with uncomplicated essential hypertension, which may contribute to the increased risk of atherosclerosis in this population, is supported.

Journal ArticleDOI
TL;DR: It is strongly suggested that significant interactions exist between aldosterone and central conduit arteries and that ald testosterone might modulate arterial function in subjects with essential hypertension.

Journal ArticleDOI
TL;DR: A patient-directed hypertensive management strategy may be feasible for patients with chronic stable hypertension and may improve blood pressure control compared with usual office-based care, at least in the short term.

Journal ArticleDOI
TL;DR: PMN priming in EH patients reflects an in vivo exposure to a constant stimulus ending in oxidative stress, increased self-necrosis, and cell recruitment, which will result in endothelial damage and atherosclerosis in the long run.

Journal ArticleDOI
TL;DR: In this article, the effects of age and BP on the standard deviation (SD) and variation coefficient (VC) of ambulatory BP were examined in a community-based sample in northeastern Japan.

Journal ArticleDOI
TL;DR: The reproducibility of home blood pressure over time is superior to that of screening blood pressure, suggesting that the reliable blood pressure measurements obtained at home have a clinical significance for the diagnosis and treatment of hypertension and as a tool for evaluating the efficacy of antihypertensive drugs.

Journal ArticleDOI
TL;DR: Smokers seem to have a diminished white coat effect, as well as a lower ambulatory blood pressure throughout the day (diastolic) and at night (systolic and diastolic), which speaks for a consistently lower blood pressure in smokers as compared with nonsmokers.

Journal ArticleDOI
TL;DR: Doppler SV closely parallels independently measured LV SV but slightly underestimates SV in both normotensive and hypertensive adults, whereas aortic stroke distance yields misleading comparisons between genders or individuals of different body sizes.

Journal ArticleDOI
TL;DR: OSA is a common, easily diagnosed, and eminently treatable condition that is associated not only with disturbed sleep, loud snoring and excessive daytime sleepiness, but also with hypertension, especially resistant hypertension, a broad range of cardiovascular problems, decreased sexual functioning, memory deficits, difficulty concentrating, and changes in personality and mood.

Journal ArticleDOI
TL;DR: Results confirm the view that differential responsiveness to endogenous digitalis-like factors is a functional feature of alpha isoforms of Na/K ATPase, and show that mammalian plasma cross-reacts with an antibody to a bufodienolide Na/k ATPase inhibitor, marinobufagenin.

Journal ArticleDOI
TL;DR: A possible role for dietary magnesium in insulin resistance is suggested in a sample of nondiabetic, young adult black Americans who had been followed longitudinally.

Journal ArticleDOI
TL;DR: It is suggested that ACE/DD predicts cerebral infarction, but not cerebral hemorrhage, and that AGN/TT enhances the risk for cerebralinfarction associated with ACE/ DD.

Journal ArticleDOI
TL;DR: The data suggest that the progression of vascular disease may be differently affected in the two sexes by a different circadian blood pressure profile.

Journal ArticleDOI
TL;DR: The results indicate that acute psychological stress associated with a sudden natural disaster causes blood pressure elevation in treated hypertensive patients, and suggest the beneficial effect of beta-blockers on such a stress-associated high blood pressure.

Journal ArticleDOI
TL;DR: The pharmacokinetics and pharmacodynamics of irbesartan are not altered in renally or hepatically impaired patients, probably owing to excretion characteristic by both biliary and renal routes, or by differences in gender or age.