Showing papers in "Biomaterials in 1987"

TL;DR: HEC adhesion in CMS onto (co)polymers of hydroxyethyl methacrylate (HEMA) and methyl methacylate (MMA) was found to be optimal on the moderately wettable copolymer (mol ratio 25 HEMA/75 MMA) and in CM, complete cell spreading in CM was only observed on the positively-charged copolymers.

TL;DR: In vivo and in vitro degradation of high molecular weight poly(L-lactide) used for internal bone fixation has been investigated and a more ductile PLLA exhibiting a lower rate of degradation was prepared by extraction of low molecular weight compounds with ethyl acetate.

TL;DR: This study addresses the problem of antibiotic resistance in adhesive, biomaterial-centred infections by suggesting that this anionic, extracapsular, polysaccharide slime produced by bacteria protects them from antibiotics and sequesters critical ions from the surface of biomaterials.

TL;DR: Besides good mechanical properties the as-polymerized PLLA exhibited a microporous structure and plates and screws of this material were used for the treatment of mandibular fractures, both in dogs and in sheep.

TL;DR: A preclinical (in vitro) technique is described and the results are given for several commercially available dressings which encompass foam, film and hydrogel material categories.

TL;DR: The polymerization shrinkage of a range of poly(n-alkyl methacrylates) in the range C1 to C16, some of their isomers and the polymers of cyclic and heterocyclic methacylates have been measured using densitometry to reflect the fact that the change in molar volume on polymerizing a methacRYlate ester is reasonably constant at 22 cc/mol irrespective of the geometry of the substituent group.

TL;DR: Comparisons with the more widely used so-called 'biodegradable' polymers, poly(glycolic acid), poly(dioxanone) and the glycolic-lactic acid (90:10) copolymers are presented together with the effect of blood plasma on the degradation process.

TL;DR: Monofilaments of PHB homopolymer and two PHV-PHB copolymers have been studied in vivo and in vitro and assessed for changes in mechanical properties and topography and the elastic properties appeared to be relatively unaffected.

TL;DR: The relative phagocytic uptake was found to decrease with increasing adsorbed layer thickness i.e. longer hydrophilic polymer chains of the coating agent and consequently a greater steric stabilization effect.

TL;DR: It was concluded that, since this in vitro method is capable of reproducing some aspects of the known in vivo behaviour of 45S5, such techniques may be developed as a means of batch-testing bioactive biomaterials and investigating bone cell/biomaterial interactions.

TL;DR: Fibroblast replication and collagen synthesis were higher on plastic than on the collagen sponge, and the entire thickness of the sponge was infiltrated by fibroblasts which rapidly replicated.

TL;DR: The in vitro strength and the strength retention of self- reinforced PGA rods are clearly better than the corresponding values for self-reinforced glycolide/lactide copolymer rods which the authors developed recently.

TL;DR: In an attempt to reduce the release of potentially harmful metal ions from Co-Cr-Mo based surgical implants, a thin coating of TiN has been applied via Physical Vapour Deposition (PVD) and in vitro corrosion performance has been investigated.

TL;DR: Self-reinforced PGA/PLA composites may be used for the treatment of fractures in cancellous bone andPositive animal experiments led to clinical studies in vivo that showed that there was no difference in outcome between 2 groups of patients with displaced fractures of the ankle treated with metallic implants or P GA/PLA fibre self-reInforced implants, respectively.

TL;DR: The leptomeninges and cortex beneath the Ag-AgCl implants showed a chronic inflammatory reaction after 8 and 16 wk, and virtually all underlying neurons appeared normal.

TL;DR: These particles make the immediate control of embolus application easy and enable periodical inspection of the polymer to check the successful blockage of the vessel, and open up the method of endovascular occlusion to further improvement.

TL;DR: It was observed that upon immobilization the affinity of GOD towards glucose was substantially decreased, and increasing the GOD content of the membrane adversely affected the activity, and Membranes with the highest enzyme activity were found to be the most permeable.

TL;DR: This study has demonstrated that the use of a bioerodible gelatin coating, with its ability to promote cellular regeneration, is a feasible approach with which to achieve earlier and more complete biological healing.

TL;DR: Chinese hamster ovary fibroblasts, as model cells, have been microencapsulated in a HEMA-MMA by interfacial precipitation to lead to hybrid artificial organs which are capable of ameliorating metabolic disorders such as diabetes.

TL;DR: The data argue for a random distribution of structurally independent anticoagulant and anticomplementary sites along the macromolecular chains of substituted dextrans.

TL;DR: Results indicate that temperatures noted at the tooth surface, within the mouth, during fluid intake were less than the temperatures of the fluid imbibed, and it is suggested that closer alignment with the clinical situation is desirable.

TL;DR: Forty extracted molar teeth were stored in saline and restored with either a microfine or hybrid composite in conjunction with a dentine adhesive, finding that the degree of movement observed with the microfine material was nearly double that recorded with the hybrid.

TL;DR: This study demonstrates that stricter manufacturing standards for metallurgical properties would serve to enhance corrosion resistance and improve the in vivo performance of stainless steel internal fixation devices.

TL;DR: Sepiolite, a magnesium silicate, binds collagen resulting in a complex which has a gel-like structure when hydrated, and this material should be considered in the design of biomaterials.

TL;DR: Copolystyrene resins are described and it is demonstrated that the activity developed by each carboxyl group is at least roughly the same as the activity of one sulphonate group, except in the case of aspartic acid sulphamide resin for which a cooperative effect is shown.

TL;DR: In vivo leucocyte interactions with the NHLBI-DTB primary reference materials, low density polyethylene (LDPE) and silica-free polydimethylsiloxane (PDMS), were qualitatively and quantitatively characterized using a cage implant system over a 21 d implantation period.

TL;DR: The significance and prospects of the use of biochemical methods to characterize connective tissue reaction to implanted synthetic polymer materials and the necessity of carrying out complex quantitative analysis of capsules developing around the implants is emphasized.

TL;DR: The heparin surface showed some specific alterations after implantation but its capacity to inhibit thrombin was not impaired and caused less intimal hyperplasia and thrombi than non-heparinized tubings.

TL;DR: The combination of the easy gelling characteristics of the alginate with the range of desirable properties (e.g. biocompatibility) afforded by the acrylic monomers may have a significant impact on the development of cell microencapsulation technology.