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Showing papers in "Computer Methods and Programs in Biomedicine in 1995"


Journal ArticleDOI
TL;DR: A Monte Carlo model of steady-state light transport in multi-layered tissues (MCML) has been coded in ANSI Standard C; therefore, the program can be used on various computers as mentioned in this paper.

2,678 citations


Journal ArticleDOI
TL;DR: A new computer program is developed that includes those statistical procedures commonly encountered in the medical literature and in statistical textbooks for medical researchers that have been identified as one of the factors involved in the misuse of statistics.

487 citations


Journal ArticleDOI
TL;DR: The paper describes two of these: a library of FORTRAN functions and subroutines and a Pascal PC program that runs under MS-DOS that exists in different versions.

93 citations


Journal ArticleDOI
TL;DR: By applying the inverse atlas transformation, images from a patient can be transformed to conform to the anatomy of the atlas brain, bringing data from different individuals into a compatible form providing possibilities to perform individual-group and group-by-group comparisons between patients and normal controls.

73 citations


Journal ArticleDOI
TL;DR: In a recent review of literature, a committee of the American Institute of Medicine found much support of the weakness of the paper-based patient record, and a local survey was held among practicing clinicians to test whether they could subscribe the Committee's conclusions.

53 citations


Journal ArticleDOI
TL;DR: HUSAR as mentioned in this paper is a collection of third-party, as well as in-house developed or adapted, sequence manipulation and analysis tools, well integrated into the UNIX operating system environment and accessible via consistent menu-aware interface.

51 citations


Journal ArticleDOI
TL;DR: A new 3-D technique for the segmentation and quantification of human spontaneous intra-cerebral brain hemorrhage (ICH) is presented and results are presented which were computed on real ICH patient brain data.

45 citations


Journal ArticleDOI
TL;DR: The authors report the development of artificial intelligence (LISP based) software that can reliably score these Content Analysis Scales, whose achievement facilitates the application of these measures to biomedical and neuropsychiatric research.

41 citations


Journal ArticleDOI
TL;DR: The validation of the DILEMMA model carried out to date is summarised, and a quick look at the place of protocols in the wider context of clinical decision support is taken.

35 citations


Journal ArticleDOI
TL;DR: A data smoothing program, OOPSEG, which automatically quantitates and filters the random measurement error in a given data series, and may have numerous applications in data analysis and experimental design.

35 citations


Journal ArticleDOI
TL;DR: A computer program designed to fit a multi-state Markov model with covariables, with a particular emphasis on the analysis of survival data, is discussed, illustrated by using a four-state model to determine factors influencing diabetic retinopathy in young subjects with insulin-dependent diabetes mellitus.

Journal ArticleDOI
TL;DR: A new approach to structural texture analysis is developed that assumes that texture consists of homogeneous regions (texture primitives), and methods for the segmentation of regions and lines in grayscale images are implemented.

Journal ArticleDOI
TL;DR: The program presented here should provide a useful starting point for those wishing to incorporate genetic algorithm approaches to LabVIEW mediated optimization of closed loop control instruments.

Journal ArticleDOI
TL;DR: An approach to classifying evaluative studies of automated information systems in health care is discussed and it is observed that certain study designs, data collection methods, and effect measures are hardly to be found in the literature.

Journal ArticleDOI
TL;DR: A computer program is described that allowed us to link a physiologically based pharmacokinetic (PBPK) model for lactational transfer of PCE in the lactating mother with the estimate of extra cancer risk for breast-fed infants, according to the U.S. Environmental Protection Agency (EPA) methodology.

Journal ArticleDOI
TL;DR: The present investigations, based on studies of the toxicology of inhaled reactive gases in the respiratory tract of rodents, provide computer programs for the generation of finite element meshes from serial tissue cross-sections that permit simulation of fluid flow in the complex geometries and local solute mass flux to the vessel walls of biological systems.

Journal ArticleDOI
TL;DR: A program for automatic and periodic determination of respiratory mechanics in artificially ventilated patients is described and it proved to work in ICU and anaesthesia patients with various ventilators.

Journal ArticleDOI
TL;DR: A platform to simulate time-varying physiological pharmacokinetic models was developed using the commercially available programming software MATLAB, based upon a library of pharmacokinetics blocks which mimic physiological structure.

Journal ArticleDOI
TL;DR: This computer program was designed to be used instead of a stimulator and an oscilloscope in whole-cell voltage-clamp experiments and can be used without interrupting the experiment, including I-V relationships, cursor measurements, addition and subtraction of obtained currents.


Journal ArticleDOI
TL;DR: MBW effectively differentiates regular and non-regular epochs while ApEn differentiates them in a less optimal manner especially in cases where higher degrees of noise are present but regularity is still observed visually.

Journal ArticleDOI
TL;DR: A dynamic compartmental model is developed to describe the redistribution of fluid and albumin between the circulation and the intact and injured interstitia following burn injury in humans and is in reasonable agreement with the limited experimental data available from the literature.

Journal ArticleDOI
TL;DR: The conclusion of the study is that the development and spread of hypermedia systems in health care may require considerable changes in current design routines and organizations.

Journal ArticleDOI
TL;DR: A marker-free video measurement and image processing method that provides numerical estimation of the 2-D centre of rotation of one rigid segment is tested and its accuracy has been tested by a comparison with in vivo radiological measurements on humans.

Journal ArticleDOI
TL;DR: The developed system described here is used as a research instrument to investigate the impact of automated protocols on the medical decision making of physicians.

Journal ArticleDOI
TL;DR: A semi-automatic segmentation algorithm was developed to reduce the information to a quadriliteral surface-representation of the teeth and the bone in a three-dimensional representation of an ideal human jaw reconstructed from a series of 178 digitized photographic cross-sections.

Journal ArticleDOI
TL;DR: The health resource allocation problem is discussed in this paper and an object-oriented system, which consists of two parts is proposed and its implemented prototype is illustrated.

Journal ArticleDOI
TL;DR: A microbiological image processing system used to determine both morphometry and fluorimetry data on (mainly faecal) bacteria is developed, which can generate scatter plots using the actual bacterial shapes, rather than arbitrary symbols.

Journal ArticleDOI
TL;DR: A computer method designed to recognize eye movements originating from vestibulo-ocular reflex signals seems to function correctly and accurately, and has been taken into use for eye movement investigations of patients suffering from otoneurological diseases.

Journal ArticleDOI
TL;DR: The paper sheds light on the infrastructural and financial aspects until the year 2000 and the need for a strategy on European level is highlighted in order to facilitate the introduction of telemedicine on a European wide scale.