Showing papers in "Computer Methods and Programs in Biomedicine in 1996"

TL;DR: MIXOR provides maximum marginal likelihood estimates for mixed-effects ordinal probit, logistic, and complementary log-log regression models, used for analysis of dichotomous and ordinal outcomes from either a clustered or longitudinal design.

TL;DR: MIXREG is a program that provides estimates for a mixed-effects regression model (MRM) for normally-distributed response data including autocorrelated errors, utilizing both the EM algorithm and a Fisher-scoring solution.

TL;DR: Pre-hepatic insulin secretion is calculated during mealolerance test, frequently sampled intravenous glucose tolerance test, hyperinsulinaemic euglycaemic glucose clamp, and basal conditions with frequent sampling.

TL;DR: A fully automatic technique to detect the breast border and the nipple is developed, this being a necessary prerequisite for further image analysis.

TL;DR: The domain of medical informatics (including health informatics), its aim, methods and tools, and its relevance to other disciplines in medicine and health sciences are outlined.

TL;DR: The digital MacReflex system for wireless recording of movements in three dimensions equipped with real-time video processors for computation of position co-ordinates for the markers and for optimised data transmission and storage is described.

TL;DR: An overview of computer-based prototypes for the provision of therapeutic advice and the generation of glycaemic predictions in insulin-dependent (type 1) diabetic patients is provided, and a model of the glucoregulatory system developed for patient and medical staff education about type 1 diabetes mellitus is reviewed.

TL;DR: This telemedicine CSCW system has been applied to build a cooperative medical imaging diagnosis application, in which two doctors, located in different hospitals, need to achieve a cooperative diagnosis on haemodynamic studies using cardiac angiography images.

TL;DR: An algorithm based on non-adaptive random search followed by stochastic gradient to determine optimal sampling times for parameter estimation in various pharmacokinetic models according to ED, EID and API criteria, which combines the robustness of RS and the speediness of SG.

TL;DR: The objective is to demonstrate several adaptive 'asymmetric' robust estimators which utilize sample selector statistics to identify the underlying distribution and to demonstrate the efficiency of these adaptive estimators.

TL;DR: The results show that the AR method offers a superior performance over the FFT method as regards the assessment of tricuspid and mitral valve stenosis.

TL;DR: Different approaches to the analysis of biological signals based on non-linear methods, despite the greater methodological and computational complexity is, in many instances, more successful compared to linear approaches, in enhancing important parameters for both physiological studies and clinical protocols.

TL;DR: Digital image analysis showed that digital image analysis is a non-invasive technique allowing repetitive and quantitative analysis of skin erythema which can be used to monitor pathophysiological changes in the body as well as the result of their treatment.

TL;DR: A performance evaluation of the DIABETES rule-based expert system prototype for clinical decision making, which facilitates multiple insulin regimen and dose adjustment of insulin dependent Type I or II diabetic patients, shows potential benefits in terms of cost saving and education and training of medical personnel.

TL;DR: The FF approach is a viable alternative for state estimation in a noisy environment and with an uncertain mathematical model of the glucoregulatory system.

TL;DR: A new procedure specific for the determination of the analytical form of the model weighting function of a complex multicomponent pharmacokinetic system with or without a shunt and time delays is described.

TL;DR: The ability of DIAS to identify periods of hypoglycaemia with reasonable accuracy illustrates how the advanced technology it employs may provide reliable decision support to clinicians.

TL;DR: A low cost digital image processing device (frame grabber) together with a program running under MS_WINDOWS for automatic on-line analysis of diameter changes of in vitro pressurized blood vessels with an inner diameter of 80-400 microns is presented.

TL;DR: A menu-driven, user-friendly PC program written in Borland Pascal is introduced which performs linear and quadratic discriminant analysis for g > or = 2 groups allowing for the incorporation of misclassification costs.

TL;DR: It is concluded that mandatory protocol consultation using ProtoVIEW influenced protocol adherence positively and residents changed their treatments almost four times more often towards the protocol than during the control periods.

TL;DR: The general linear parametric multivariate modelling concept is presented, and it is shown that the classic strictly-causal structure must be abandoned in order to utilise the modelling in many practical situations.

TL;DR: Cardionomic is a portable computerised system used for a guided step-by-step performance of several cardiovascular tests for autonomic neuropathy and represents a valid alternative for the routine screening of autonomic Neuropathy.

TL;DR: It is found that a typical hypoglycaemic counter-regulation begins 6-8 h after the Hypoglycaemia, that it lasts 16-18 h, giving a total duration of 24 h, and that it elevates the blood glucose by 4-10 mmol/l.

TL;DR: A compartment model of the transport of oxygen from the alveoli to the tissues is described, and in patients with both pulmonary shunt and alveolar resistance to diffusion of oxygen, the model is used to simulate their response to variations in the inspired oxygen fraction.

TL;DR: A decision support system for laboratory capacity management contains a simulation module for determining the performance of planning rules given the equipment and staffing of the clinical laboratory and the demand for laboratory services.

TL;DR: It is demonstrated that physiologically meaningful information about the causal interactions in the cardiovascular system can be drawn from the routinely available clinical signals.

TL;DR: For both local and remote trouble-shooting, the data provided by the instrument and connected workstation is of paramount importance for the efficiency and accuracy of the diagnosis and the importance of standardization of telemaintenance communication protocols is addressed.

TL;DR: Methods for signal processing of EEG for this purpose must include time domain assessment and recognition of burst suppression pattern, as well as frequency domain information, and provide multivariate pattern recognition.

TL;DR: A nurse with no previous experience of managing type II diabetes was trained to use the system and then undertook the exclusive management of half of all new type II diabetics, from a district population of 300,000, over a 16-month period.

TL;DR: A computer program for use in the design of long-term clinical trials with multiple treatment arms in which the primary outcome variables are censored survival times and Fisher's LSD method is used to adjust for the multiple comparisons.