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Showing papers in "European Urology in 2005"


Journal ArticleDOI
Claire L Vale1
TL;DR: In this paper, a systematic review and meta-analysis of updated individual patient data from all available randomised controlled trials comparing local treatment plus adjuvant chemotherapy versus the same local treatment alone was conducted.

1,063 citations


Journal ArticleDOI
TL;DR: Clinical evidence is insufficient to warrant the substitution of the cystoscopic follow-up scheme by any of the currently available urine marker tests, and Microsatellite analysis, ImmunoCyt, NMP22, CYFRA21-1, LewisX and FISH are the most promising markers for surveillance at this time.

467 citations


Journal ArticleDOI
TL;DR: This update presents the state-of-the-art management of testicular cancer patients in 2005, and concludes that guidelines will improve clinical practice only if they are regularly updated.

404 citations


Journal ArticleDOI
TL;DR: This IPD meta-analysis provides the best evidence currently available on the role of adjuvant chemotherapy for invasive bladder cancer, however, at present there is insufficient evidence on which to reliably base treatment decisions.

335 citations


Journal ArticleDOI
TL;DR: Overall, 32.2% of men in this study had ED according to the IIEF-5, and most important risk factors were diabetes, hyperlipidemia, lower urinary tract symptoms, hypertension and psychological stress.

315 citations


Journal ArticleDOI
TL;DR: The genitourinary trauma literature still relies heavily on expert opinion and single-institution retrospective series, and future prospective trials of the most significant issues, when possible, might improve the quality of evidence that dictates practitioner behavior.

305 citations


Journal ArticleDOI
TL;DR: Solifenacin, with a flexible dosing regimen, was found to be superior to tolterodine ER with respect to the majority of the efficacy variables.

295 citations


Journal ArticleDOI
TL;DR: The use of the f/tPSA or cPSA test among men with PSA levels between 2 and 10 ng/ml can reduce the number of unnecessary biopsies whilst maintaining a high cancer detection rate.

267 citations


Journal ArticleDOI
TL;DR: This large-scale, contemporary, nation-wide analysis confirms the higher reoperation rate after TURP compared to open PE and observes no excess risk of myocardial infarction or death after T URP comparedto open PE.

260 citations


Journal ArticleDOI
TL;DR: Metastasectomy nowadays is the best treatment option in cases with technical resectable metastases with as much as possible good prognostic factors (metachronous metastase with long DFI, number up to 6 metastases).

259 citations


Journal ArticleDOI
TL;DR: Chronic therapy with TAD improves endothelial function in patients with increased cardiovascular risk regardless their degree of ED, and the benefit of this therapy is sustained for at least two weeks after the discontinuation of therapy.

Journal ArticleDOI
TL;DR: The need to improve the understanding of the biological nature of PC, especially cancer cells of the NE phenotype and their regulatory products to develop new therapeutic protocols and trials based on NE hormones and their agonists/antagonists is shown.

Journal ArticleDOI
TL;DR: PVP provides excellent intraoperative safety, instant tissue removal, and immediate relief from obstructive voiding symptoms, similar to TURP, and early outcomes 6-months after PVP and T URP are comparable.

Journal ArticleDOI
TL;DR: The antimuscarinics have different tolerability and safety profiles, which are clinically significant, and there were significant differences in rates of withdrawal and rates and range of adverse events and efficacy outcomes.

Journal ArticleDOI
TL;DR: Patients with muscle-invasive bladder cancer and a history of superficial bladder cancer have a worse prognosis than patients with primary Muscle-in invasive bladder cancer.

Journal ArticleDOI
TL;DR: Laroscopic promonto-fixation is feasible and highly effective technique that offers good long-term results with complication rates similar to open surgery, with the added benefits of minimally invasive surgery.

Journal ArticleDOI
TL;DR: After RRP an early supportive rehabilitation program like PFMT significantly reduces continence recovery time and is effective on a large population of patients that had undergone radical retropubic prostatectomy.

Journal ArticleDOI
TL;DR: It appears that the pathophysiological mechanisms of LUTS and the related prostatic enlargement of BPH as well as certain treatments for this condition may have an impact on both the erection and ejaculation components of the sexual response.

Journal ArticleDOI
TL;DR: The issue of an "alternate explanation" to describe the LUTS-ED association appears to be accounted for in that several large studies have provided convincing multiple regression analyses in which the ED-LUTS relationship remains significant.

Journal ArticleDOI
TL;DR: A guideline text is presented providing an overview of key issues involved in the patients' management such as assessment of donors, pre-transplant evaluation, techniques, management, post-trans transplant care, etc.

Journal ArticleDOI
TL;DR: Urologists should be aware that bicycling is a potential and not an infrequent cause of a variety of urological and andrological disorders caused by overuse injuries affecting the genitourinary system.

Journal ArticleDOI
TL;DR: In this complete nation-wide series nuclear grading is important in predicting survival of patients with RCC, and is strongly related to both tumor size and stage, with stage being by far the strongest prognostic factor.

Journal ArticleDOI
TL;DR: The depth of invasion in the TURB specimens is an independent prognostic factor for T1 bladder cancer even in BCG-treated patients and supports that routine pathological assessment of the level of MM invasion in patients with stage T2 bladder cancer should be included in the histopathological report.

Journal ArticleDOI
TL;DR: It is demonstrated that testosterone positively regulates PDE5 expression and in vivo responsiveness to PDE4 inhibitor, tadalafil, in the rat corpus cavernosum.

Journal ArticleDOI
TL;DR: It is demonstrated that decompression of the pudendal nerve is an effective and safe treatment for cases of chronic pUDendal neuralgia that have been unresponsive to analgesia and nerve blocks following surgical intervention.

Journal ArticleDOI
TL;DR: Potassium paraaminobenzoate appears to be useful to stabilize the disorder and prevent progression of penile curvature and a significant protective effect on deterioration of peniles curvature could be demonstrated.

Journal ArticleDOI
TL;DR: PNL is currently the procedure of choice for removal of large renal calculi and the need for well designed prospective randomized trials comparing PNL with alternative treatment modalities arises through the literature review.

Journal ArticleDOI
TL;DR: Moderate to severe ED, but not mild ED is associated with a considerably increased risk for CHD or stroke within 10 years and a thorough medical surveillance seems advisable for men with ED.

Journal ArticleDOI
TL;DR: The high prevalence of OAB in this population, its negative impact of quality of life and sexuality underline the importance of this syndrome.

Journal ArticleDOI
TL;DR: Findings support the strategy that patients with ED should undergo further cardiovascular evaluation, as a considerable proportion of patients withED of vascular origin has angiographically documented silent CAD.