Showing papers in "Experimental Parasitology in 1984"

TL;DR: A cell-free liquid medium has been devised for serial cultivation of Leishmania mexicana pifanoi amastigotes at 33 and 35 C and, when transferred into the modified medium and incubated at 26 C, the amASTigotes entirely transformed into promastigote after three serial passages.

TL;DR: It is demonstrated that autoinfection occurs in dogs infected with S. stercoralis and that, if it is allowed to continue for a sufficiently long time in immunosuppressed hosts, massive hyperinfection, and even disseminated infection, may occur.

TL;DR: There appears that there are significant physiological and pharmacological differences between circular and longitudinal muscles in the adult male schistosome.

TL;DR: The results suggest that 10-R2 serum possesses a heat-labile factor which specifically activate B. glabrata hemocytes to encapsulate and destroy sporocysts whereas PR albino serum lacks this factor.

TL;DR: There are some similarities in the proteolytic activities of all three trichomonad species, and that the two parasites of the urinogenital tracts of mammals possess additional features in common.

TL;DR: The pharmacological evidence is consistent with a neurotransmitter role of acetylcholine, dopamine, dopamine (excitatory), and noradrenaline (inhibitory) and the status of serotonin, which causes a marked stimulation of motility.

TL;DR: It is concluded that recordings of intestinal myoelectric activity provide sensitive, quantifiable correlates of contractile patterns throughout the intestinal phase of trichinellosis in a single host.

TL;DR: An altered thiol status in the G6 PD-deficient erythrocytes could underlie the selective advantage of G6PD deficiency in the presence of malaria.

TL;DR: The effects of a wide range of fasciolicides on the in vitro motility of Fasciola hepatica have been determined by means of an isometric transducer system, finding that mebendazole at 500 micrograms/ml causes total inactivity of the fluke within a 12-hr period.

TL;DR: Parasites were recovered from intravenously inoculated cats as long as 16 weeks after inoculation, but parasites apparently did not locate in the viscera in cats inoculated intradermally.

TL;DR: It appears from this and histological evidence that an erythrocyte substance, released by mosquito digestion, is needed for ookinete invasion of the gut epithelium.

TL;DR: The data presented are consistent with a colloid osmotic mechanism of lysis induced by irreversible acute damage to the normal permeability properties of the trypanosome plasma membrane.

TL;DR: The fraction of asymmetrically labeled trophozoites is consistent with a model in which the nuclei replicate out of phase by 15-30 min, but, due to the small diameter of the nuclea relative to the grain size, the possibility that replication takes place simultaneously in both nuclei of a trophozite throughout the S phase cannot be ruled out.

TL;DR: The fully developed resistance was stable in organisms maintained in the absence of the drug over 2 years, and the substrains with unstable resistance regained the susceptibility to high concentrations of metronidazole after 80 to 100 transfers in drug-free media.

TL;DR: The asexual development cycle of Plasmodium falciparum, a malarial parasite of humans, has been synchronized in culture by treating ring-stage parasites with aphidicolin, an inhibitor of DNA synthesis.

TL;DR: Immunoreactive glycoproteins of Schistosoma mansoni, S. haematobium, and S. japonicum adult worms which are genus-, species-, and gender-specific, or react with sera of patients infected with other parasites, have been identified.

TL;DR: Experimental and supporting evidence is presented that behavioral modification resulted from functional impairments to receptors located within chemosensory sensilla.

TL;DR: This study provides an explanation for the extensive cross-reactivity observed in diagnostic assays which utilize various fractions of schistosomal egg extracts as the antigen.

TL;DR: The fact that similar concanavalin A binding was not seen on microfilariae recovered directly from the infected host implies that there is masking or loss of parasite surface antigens as microFilariae mature in vivo.

TL;DR: Adult flukes, Fasciola hepatica, incubated in Hedon - Fleig saline containing concanavalin A for 10 and 45 min, respectively, exhibited severe alterations to tegumental morphology involving increased secretory activity, blebbing of the apical plasma membrane, increased total surface area, and swelling of the basal infolds.

TL;DR: Measurement of changes in levels of circulating antigens by immunoradiometric assays with stage-specific monoclonal antibodies provides a new means of assessing the efficacy of drugs and their site of action in onchocerciasis.

TL;DR: The cuticular/muscle tissue largely appears to be the primary route of absorption of cholesterol and glucose in adult A. suum, and Occlusion of the digestive tract had no effect on the short-term absorption of 3H-labeled cholesterol, [14C]-3-o-methylglucose or [14 C]glucOSE from the incubation medium into the perienteric cavity.

TL;DR: In all specimens, 5-hydroxytryptamine was the highest while norepinephrine was found to be uniformly low and the female reproductive organ contained the maximum amount of dopamine while intestine was rich in histamine.

TL;DR: Both the agglutination and gel-formation phenomena may facilitate recognition of, and attacks on, sporocysts, thereby contributing to susceptibility and resistance in this host-parasite system.

TL;DR: Although the overall growth rates were consistently lower than in control cultures with plasma, continuous growth occurred in the absence of plasma in cultures containing cis-vaccenic, oleic, and linoleic acids.

TL;DR: The in vivo effects of a single oral dose of oxamniquine on the ultrastructure of Schistosoma mansoni were investigated, and severe disruption of the tegument and gastrodermis took place, and extensive extracellular spaces developed between the cells of the internal tissues.

TL;DR: The results obtained are compatible with resistance being a recessive trait controlled by a single autosomal gene (or gene cluster) and in addition, sex-associated factors appear to confer higher resistance in females.

TL;DR: It appears, in cattle, resistance mechanisms are effective against challenge flukes at or soon after penetration of the liver, as assessed by recovery of flukes from the liver 15-16 weeks after challenge.

TL;DR: The nematode Trichinella spiralis is rejected from the intestine at a time that is characteristic for each inbred strain of mouse, and it is demonstrated that time of rejection is directly proportional to dose in all inbred and F1 mouse strains that the authors have examined.

TL;DR: Results indicate that the gastric hyperplasia is caused by stimulation of growth and major differentiation of stem cells to neutral mucus-producing cells.