E
Eric S. Loker
Researcher at University of New Mexico
Publications - 61
Citations - 4635
Eric S. Loker is an academic researcher from University of New Mexico. The author has contributed to research in topics: Schistosoma mansoni & Biomphalaria glabrata. The author has an hindex of 31, co-authored 45 publications receiving 4163 citations. Previous affiliations of Eric S. Loker include Oregon State University.
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Invertebrate immune systems--not homogeneous, not simple, not well understood.
TL;DR: Data suggest that novel immune capabilities will be found among the different invertebrate phyla, and a model is presented that supports the adaptive value of diversified non‐self recognition molecules in invertebrates.
Journal ArticleDOI
Diversification of Ig Superfamily Genes in an Invertebrate
TL;DR: It is shown that the IgSF1 domain of the FREP3 subfamily is diversified at the genomic level at higher rates than those recorded for control genes.
Journal ArticleDOI
Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni.
Sandra D. Melman,Michelle L. Steinauer,Charles E. Cunningham,Laura Kubatko,Ibrahim N. Mwangi,Nirvana Barker Wynn,Martin W. Mutuku,Diana M. S. Karanja,Daniel G. Colley,Carla L. Black,William Evan Secor,Gerald M. Mkoji,Eric S. Loker +12 more
TL;DR: Isolates of S. mansoni from some patients in Kisumu have lower susceptibility to PZQ, including one from a patient who was never fully cured after repeated rounds of treatment administered over several years.
Journal ArticleDOI
A family of fibrinogen-related proteins that precipitates parasite-derived molecules is produced by an invertebrate after infection
TL;DR: Three different cDNAs with sequence similarities to peptides derived from the 65-kDa lectins were obtained and unexpectedly found to encode fibrinogen-related proteins (FREPs) and these FREPs contained regions with sequence similarity to Ig superfamily members.
Journal ArticleDOI
Whole genome analysis of a schistosomiasis-transmitting freshwater snail.
Coen M. Adema,LaDeana W. Hillier,Catherine S. Jones,Eric S. Loker,Matty Knight,Matty Knight,Patrick Minx,Guilherme Oliveira,Nithya Raghavan,Andrew M. Shedlock,Laurence Rodrigues do Amaral,Halime D. Arican-Goktas,Juliana G Assis,Elio Hideo Baba,Olga Baron,Christopher J. Bayne,Utibe Bickham-Wright,Kyle K. Biggar,Michael S. Blouin,Bryony C. Bonning,Chris Botka,Joanna M. Bridger,Katherine M. Buckley,Sarah K. Buddenborg,Roberta Lima Caldeira,Julia B. Carleton,Omar dos Santos Carvalho,Maria G. Castillo,Iain W. Chalmers,Mikkel Christensens,Sandra W. Clifton,Céline Cosseau,Christine Coustau,Richard M. Cripps,Yesid Cuesta-Astroz,Scott F. Cummins,Leon di Stephano,Leon di Stephano,Nathalie Dinguirard,David Duval,Scott J. Emrich,Cédric Feschotte,René Feyereisen,Peter C. FitzGerald,Catrina Fronick,Lucinda Fulton,Richard Galinier,Sandra Grossi Gava,Michael E. Geusz,Kathrin K. Geyer,Gloria I. Giraldo-Calderón,Matheus de Souza Gomes,Michelle A. Gordy,Benjamin Gourbal,Christoph Grunau,Patrick C. Hanington,Karl F. Hoffmann,Daniel S.T. Hughes,Judith E. Humphries,Daniel J. Jackson,Liana K. Jannotti-Passos,Wander de Jesus Jeremias,Susan Jobling,Bishoy Kamel,Aurélie Kapusta,Satwant Kaur,Joris M. Koene,Andrea B. Kohn,Daniel Lawson,Scott P Lawton,Di Liang,Yanin Limpanont,Sijun Liu,Anne E. Lockyer,TyAnna L. Lovato,Fernanda Ludolf,Vince Magrini,Donald P. McManus,Mónica Medina,Milind Misra,Guillaume Mitta,Gerald M. Mkoji,Michael J. Montague,Cesar E. Montelongo,Leonid L. Moroz,Monica Munoz-Torres,Umar Niazi,Leslie R. Noble,Francislon Silva de Oliveira,Fabiano Sviatopolk-Mirsky Pais,Anthony T. Papenfuss,Anthony T. Papenfuss,Rob Peace,Janeth J. Pena,Emmanuel A. Pila,Titouan Quelais,Brian J. Raney,Jonathan P. Rast,David Rollinson,Izinara C Rosse,Bronwyn Rotgans,Edwin J. Routledge,Kathryn M. Ryan,Larissa L. S. Scholte,Kenneth B. Storey,Martin T. Swain,Jacob A. Tennessen,Chad Tomlinson,Damian L. Trujillo,Emanuela V. Volpi,Anthony J. Walker,Tianfang Wang,Ittiprasert Wannaporn,Wesley C. Warren,Xiao-Jun Wu,Timothy P. Yoshino,Mohammed Yusuf,Mohammed Yusuf,Si-Ming Zhang,Min Zhao,Richard K. Wilson +120 more
TL;DR: Parts of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata are described and several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis are identified.