Showing papers in "Journal of Chromatography A in 2021"

TL;DR: This review focuses on recently emerging and modern EV isolation and separation techniques, including size-, charge-, and affinity- based techniques while excluding ultracentrifugation and precipitation-based techniques due to their multiple limitations.

TL;DR: This review focuses on the specificity of recent extraction techniques and the influence of their physical parameters (i.e. pressure, intensity, etc.) on selectivity.

TL;DR: In this paper, the authors compare and contrast sample preparation techniques coupled with high-performance liquid chromatography (HPLC) and describe applications developed in biomedical, forensics, and environmental/industrial hygiene in the last two decades.

TL;DR: The present state of IT-SPME technology is described and its current trends and future perspectives are summarized, including method development and strategies to improve extraction efficiency.

TL;DR: The development status and prospects of SBSE as an efficient sample pretreatment technique in real sample analysis are discussed, along with their respective advantages in extraction process and application in trace analysis.

TL;DR: The aim of this study was to selectively extract bioactive compounds and pigments from rosemary using supercritical fluid extraction and to study how the selected conditions impacted their extraction.

TL;DR: The paper presents the first application of deep eutectic solvents (DES) as stationary phases for gas chromatography and retention data collected indicate the possibility of its application to other separation techniques, i.e. extractive distillation.

TL;DR: In this paper, a review of methods and strategies for reducing the number of stationary and mobile phases of a chiral stationary-phase is presented, with the main objective of this review being to revisit, critically discuss and compile the solutions published over the last two decades.

TL;DR: In this article, the authors summarized current knowledge and applications of the new extraction techniques such as supercritical fluid extraction, pressurized liquid extraction, ultrasound assisted extraction applied to polyphenols extraction from agricultural food byproducts.

TL;DR: This article comprehensively highlights the most historical microsampling technique, the dried blood spot (DBS), and its development and delineates the involvement of other biological fluids and their miniaturized dried matrix forms in TDM.

TL;DR: A review of the most commonly used analytical methodologies for detecting both cannabinoids and terpenes is described in this paper, where well-established and innovative extraction protocols, and chromatographic separations, such as GC and HPLC, are reviewed highlighting their respective advantages and drawbacks.

TL;DR: In this paper, the main theoretical aspects related to deep eutectic solvents (DES), switchable hydrophilicity (SHS) and supramolecular (SUPRAS) are discussed.

TL;DR: In this article, a review examines the recent developments and applications of sample preparation techniques for illicit drugs in solid, liquid, and gas samples, and introduces recently developed instrumental techniques applied to detect illicit drugs.

TL;DR: The present overview is not to present an extensive review of the literature on chiral CEC but to analyze the reasons for this dramatic development and attempt to answer questions such as: Was the potential of CEC reasonably evaluated in 1990s before starting the explosive development in this field?

TL;DR: In this article, a robust eight-dimensional hyphenation of separation and detection techniques is developed, which is applicable for routine, allowing the non-target high-throughput screening of complex samples for individual bioactive compounds.

TL;DR: In this article, a core-shell structured magnetic covalent organic framework named as M-TpDAB was constructed with 3,3′-diaminobenzidine (DAB) and 1,3,5-triformylphloroglucinol (Tp) as building units.

TL;DR: In this article, a new liquid-liquid microextraction approach by applying a deep eutectic solvent was adopted for the extraction of four antibiotics (penicillin G, dihydrostreptomycin, enrofloxacin, and ciprofloxinacin) from honey samples.

TL;DR: An overview of the two commonly employed approaches used for polyphenol analysis, viz RP-LC×-RP-LC and HILIC-LC, can be found in this article.

TL;DR: A unique international collaboration is described that lead to the development of a robust SOP for the measurement of physical-chemical properties of nanopharmaceuticals by multi-detector AF4 (MD-AF4) involving two state of the art infrastructures in the field of nanomedicine.

TL;DR: The proposed method with simple operation, short pre-concentration time and high sensitivity has been successfully applied to mercury speciation at trace levels in the samples with complicated matrices, including underground water, surface water, sea water and fish samples.

TL;DR: Compared analyzing recent developments that address limitations of DEP-FFF is a step forward towards realizing the full potential of the technique as an ideal candidate for point-of-care (POC) devices with diverse applications in the fields of biomedical, chemical, and environmental engineering.

TL;DR: In this paper, an autoTLC−LC−MS system is introduced for orthogonal hyphenation of normal phase high-performance thin-layer chromatography with reversed phase highperformance LC (HPLC) and high-resolution MS (HRMS), taking advantage of open-source hard and software developments as well as 3D printing.

TL;DR: In this paper, the authors proposed a hybrid model based on neural network and mechanistic model to predict the chromatographic unit behavior of a biopharmaceutical process, which can be used to generate representations for the underlying principles such as adsorption equilibria and mass transfer kinetics.

TL;DR: The classification-based methodology for simplifying TCM researches was refined from literature in the past 10 years, and two perspectives are highlighted in this review: set theory is a theoretical basis for all strategies from a conceptual perspective, and liquid chromatography-mass spectrometry is a common tool for all Strategies from a technical perspective.

TL;DR: A triazine-based porous organic polymer was prepared by facile solvothermal polymerization with cyanuric chloride and triphenyl phosphine as functional monomers as mentioned in this paper, which was characterized and then used for the first time as the sorbent for the effective solid-phase extraction of some nitroimidazoles (NDZs) (metronidazole, ronidaxole, secnidazolate, dimetridazole and ornidazola).

TL;DR: A variety of CMC models have been established using different membrane receptors as a stationary phase, and many new methods have been developed by combining CMC with high-performance liquid chromatography (HPLC)/mass spectrometry or HPLC-IT-TOF technologies as discussed by the authors.

TL;DR: In this article, a simple, green, and reliable method combining vortex-assisted liquid-liquid microextraction based on in situ formation of a novel hydrophobic natural deep eutectic solvent (NADES-VA-LLME) and high-performance liquid chromatography (HPLC) was developed for the determination of metoprolol and propranolol in water samples.

TL;DR: In this paper, a 2D bimetallic metal-organic framework (Ni-ZIF-8) was synthesized by pyrolyzing Ni-Zif-8 under argon atmosphere and explored as magnetic solid phase extraction (MSPE) adsorbents for the determination of nitroimidazole antibiotics (NIABs).

TL;DR: In this article, a generic hydrophilic interaction liquid chromatography (HILIC) hyphenated with tandem mass spectrometry method was developed for oligonucleotide and siRNA analysis in the absence of ion-pairing reagents.

TL;DR: In this article, the authors reviewed the application of molecularly imprinted polymer (MIP) in the detection of chemical residues from food in the past five years and discussed the challenges faced by MIP.