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Showing papers in "Journal of Critical Care in 1999"


Journal ArticleDOI
TL;DR: Based on this physiological background, strategies and techniques are proposed that are useful for the gradual transition to spontaneous ventilation in ventilated patients with difficult to wean patients.

215 citations


Journal ArticleDOI
TL;DR: In comparison with cardiac filling pressures, ITBVI seems to be the more reliable indicator of cardiac preload in patients with sepsis or septic shock.

200 citations


Journal ArticleDOI
TL;DR: It was found that a short period of enteral fasting was associated with significant duodenal mucosal atrophy and abnormal gut permeability in critically ill patients.

167 citations


Journal ArticleDOI
TL;DR: PLV is associated with significant attenuation of lung injury, in comparison to CMV, and this effect is predominantly due to attenuations of injury in the dependent region of the lung.

75 citations


Journal ArticleDOI
TL;DR: A hyperoncotic albumin solution appears to have an inotropic effect in patients following cardiopulmonary bypass procedures, and it is shown that the pattern of respiratory variation in right atrial pressure is a useful guide to predict response to volume loading.

68 citations


Journal ArticleDOI
TL;DR: Intracellular antibody reaction against katacalcin supports the notion that various types of leukocytes contain procalcitonin, a new marker of severity of nonviral, in particular, bacterial infections.

55 citations


Journal ArticleDOI
TL;DR: It is suggested that partial liquid ventilation supports gas exchange and reduces mortality in association with a reduction in the production of reactive oxygen species and the concomitant attenuation of tissue damage during the early phase of acute lung injury.

46 citations


Journal ArticleDOI
TL;DR: It is suggested that early hepatic dysfunction plays an important role in serum lactate elevation in acute circulatory failure.

45 citations


Journal ArticleDOI
TL;DR: This study shows that IL-1ra and E-selectin are released in acute severe pancreatitis, and the levels seem to be comparable to those in patients with severe sepsis, as indicated by high SOFA scores during the first week of disease.

42 citations


Journal ArticleDOI
TL;DR: Development and implementation of a prophylactic ketoconazole practice guideline for ICU patients at high risk of ARDS was associated with a higher prescription of ketoconzole and a lower rate of AR DS in the study hospital than in the control hospital.

33 citations


Journal ArticleDOI
TL;DR: This study suggests that specific antianaerobic therapy may be considered in the choice of empirical antibiotherapy in patients with nosocomial pneumonia.

Journal ArticleDOI
TL;DR: E efficacy of inhaled NO in improving oxygenation was moderate and difficult to predict, response to first NO inhalation was not associated with prognosis, and treatment of the most severe ARDS patients with inhaled No did not influenced their intensive care unit survival.

Journal ArticleDOI
TL;DR: Intagastric tonometry is recommended to be performed in the fasting state and discourage tonometry after feeding as a stress test, because a single test meal changes tonometric PrCO2 in a time-dependent manner until 2 hours after gastric feeding of healthy volunteers.

Journal ArticleDOI
TL;DR: It is concluded that recurrent microembolization in pigs provides a reliable model of sustained pulmonary hypertension and inhaled NO is a selective pulmonary vasodilator, indicating that active vasoconstriction significantly contributes to sustained pulmonary pulmonary hypertension after recurrent micro Embolism.

Journal ArticleDOI
TL;DR: Rats subjected to controlled ventilation and permissive hypercapnia, unlike dogs and perhaps humans, show no augmentation of Hb concentration, and it is speculated that the stronghypercapnia-induced Bohr effect in rats may prevent hypoxia at the tissue level.

Journal ArticleDOI
TL;DR: When confounding factors were controlled, HA-VAP appeared to increase mortality of severe CAP requiring ICU admission, and success of matching was achieved in 198 of 258 variables used for matching.


Journal ArticleDOI
TL;DR: Based on the simulations, the commonly used threshold value for venous [LA]/[PY] = 14 as evidence of tissue hypoxia seems appropriate during severe ischemia.

Journal ArticleDOI
TL;DR: Flow triggering offers an excellent complement to PSV because it improves patient comfort and reduces the magnitude of the inspiratory effort as well as the delay time between inspiratory muscle contraction and gas flow.

Journal ArticleDOI
TL;DR: IL-1ra administration has no effect on cardiac function in septic patients, and no significant differences in hemodynamic parameters were observed between the groups or over time during the study period.

Journal ArticleDOI
TL;DR: Thoracocardiographic reflects characteristics of left ventricular filling similar to Doppler echocardiography, which has the potential for continuous monitoring of mechanical cardiac performance.

Journal ArticleDOI
TL;DR: In this experimental rat model, the catecholamines epinephrine and norepinephrine in a dosage of 0.2 microg.kg(-1).min(-1) neither diminish nor improve mucosal villous blood flow during the early phase of endotoxemia.

Journal ArticleDOI
TL;DR: A small-scale mortality outcome for ARDS is comparable to large tertiary referral institutions, and the PIP, PEEP, and ventilation index are valuable for predicting outcome in ARDS by the third day of conventional therapy.

Journal ArticleDOI
TL;DR: In the early phase of endotoxemia in the dog, the significant reduction in systemic vascular resistance and hepatic arterial resistance are not associated with any measurable NOx release in the systemic circulation or the liver.

Journal ArticleDOI
TL;DR: In this porcine model of sepsis, dobutamine infusion significantly increases myocardial oxygen consumption and the importance of this effect as a fraction of the increase in whole-body oxygen consumption is determined.

Journal ArticleDOI
TL;DR: NO2 concentrations in the lung were significantly increased above commonly accepted toxic concentrations during ventilation with high concentrations of NO (80 ppm) and high fractional concentrations of oxygen.