Showing papers in "Journal of Critical Care in 2006"
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TL;DR: This narrative is a guide to the evolution of medical and critical care checklists, and a discussion of the barriers and risks to the implementation of checklists.
565 citations
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TL;DR: The initial retrospective validation of a pediatric severity of illness score has great potential to increase the efficiency of care delivery and to improve the outcomes of care provided to hospitalized children.
332 citations
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TL;DR: A high-quality ICU database has successfully been implemented in Australia and New Zealand and is now used as a routine quality assurance and peer review tool.
234 citations
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TL;DR: The Intensive Care Unit Safety Reporting System provides a mechanism for multiple ICUs to identify hazards and data trends show a correlation between multiple contributing factors and higher rates of harm.
215 citations
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TL;DR: The role of poorcomm unication among clinical discipli nes as a cause ofmedi cal error is investigated and ineffective comm unication is a signi ficantfactor in medi cal erro r.
208 citations
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TL;DR: Intravenous milrinone produces early improvements in oxygenation without compromising systemic blood pressure and there was a nonsignificant trend toward improved blood pressure.
168 citations
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TL;DR: In a large cohort of mechanically ventilated patients, VAP is more likely in patients with underlying lung disease (acute or chronic) and Ventilator-associated pneumonia was associated with a significant increase in ICU length of stay but no increase in mortality.
156 citations
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TL;DR: Retrospective analysis of prospectively collected data in patients admitted to the NNICU over a 6.5-year period found hypernatremia is common in the NnICU, more so in patients treated with mannitol and severe (but not mild or moderate) hypernat Remia is independently associated with increased mortality.
149 citations
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TL;DR: The current understanding of electromagnetic interference as it applies to the technology-rich critical care environment is reviewed.
90 citations
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TL;DR: The potential sources of bias and confounding in critical care research are highlighted and the statistical techniques available (matching, stratification, multivariable adjustment, propensity scores, and instrumental variables) to adjust for confounders are reviewed.
88 citations
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TL;DR: Isolation of Aspergillus in critically ill patients is a poor prognostic marker and is associated with high mortality irrespective of invasion or colonization and those who are neutropenic, on immunosuppressive therapy, on broad-spectrum antibiotics, or had bone marrow transplantation are more likely to have invasive pulmonary aspergillosis.
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TL;DR: A structure for a class of collaborative, community-wide in silico models that use the framework of agent-based modeling that will provide a functional, synthetic data base on the AIR that could be used for directing research, testing hypotheses, teaching and training, and drug discovery/testing.
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TL;DR: It is demonstrated that SIRS reflected the degree of surgical stress, especially thoracotomic procedures, through the IL-6 levels, and affected the postoperative hospital stay.
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TL;DR: Investigating longitudinally over time heart rate dynamics and relation with mortality and organ dysfunction alterations in patients admitted to a multidisciplinary intensive care unit found loss of variability and increase in periodicity in heart rate of critically ill patients are linked with parallel deterioration of organ dysfunction and high mortality.
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Boston Children's Hospital1, Johns Hopkins University2, Primary Children's Hospital3, University of California, San Francisco4, Children's Hospital Oakland5, Monroe Carell Jr. Children's Hospital at Vanderbilt6, Children's Medical Center of Dallas7, Children's Memorial Hospital8, Tufts Medical Center9
TL;DR: The process, multidisciplinary input, and procedures used to support the design of the clinical trial, as well as the challenges faced by the clinical scientists during the conduct of theclinical trial, are described.
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TL;DR: A high CRP concentration within 24 hours before ICU discharge is associated with a higher risk of readmission to the ICU.
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TL;DR: D detection of cognitive abnormalities in acute respiratory distress syndrome survivors using a telephone-administered test battery derived from standard cognitive tests is feasible and has evidence of construct validity.
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TL;DR: Risk of ARDS development is related to the first 24-hour admission variables, including severe physiologic derangements and specific ICD-9-classified injuries.
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TL;DR: Insightful insights are offered into end-of-life decision making, prompting clinicians to be conscious of the contradictions that arise and to use specific strategies to address these contradictions in their communication with families.
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TL;DR: Intrapulmonary percussive ventilation was effective and safe in improving compression atelectasis without adverse effects in obese patients and was assessed at the start of weaning.
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TL;DR: Extubation failure in patients with COPD remains high despite a successful spontaneous breathing on T piece, and Simplified Acute Physiology Score II at ICU admission, home noninvasive MV, and isolated pathogens on quantitative cultures of tracheobronchial secretions within 72 hours preceding extubation were predictors of extubations failure in the study population.
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TL;DR: In this series, ARF treated with CVVHDF was associated with a high overall ICU mortality rate (71.6%).
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TL;DR: The study designs used create opportunity for significant bias, preventing any useful inferences to be drawn, and Methodological limitations and interstudy differences in participants and transport personnel precluded pooling of results.
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TL;DR: Comparing the value of APACHE II and comorbidity scores as adjustment variables in statistical models of hospital mortality and hospital and ICU length of stay after adjustment for other covariates found the value depends on the outcome and population of interest.
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TL;DR: It is speculated that activation of circulating leukocytes and/or direct effect of NH may affect certain peripheral organs independently from the NH-induced pulmonary pathology.
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TL;DR: The HRV markedly decreased, most likely because of autonomic dysfunction, in patients with HFMD and herpangina when complicated with central nervous system involvement and cardiopulmonary failure and may be useful parameters to monitor disease progression.
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TL;DR: Patients who failed weaning in the RCC had had a longer intensive care unit and RCC stay and a worse outcome after leaving theRCC, and patients admitted to the R CC were still critically ill.
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TL;DR: Hemodialysis is not necessary for all cases of severe hyperKalemia and should be reserved for patients with acute or chronic renal failure or those with life-threatening hyperkalemia unresponsive to more conservative measures.
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TL;DR: The use of PAB makes possible a decrease in ventilator WT and a shorter stay in the ICU, with a resulting increase in functional recuperation and decrease in patient mortality.
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TL;DR: It is demonstrated how economic evaluation can link medical outcomes, quality of life, and costs in a common index, even for therapies for different medical conditions and with different health outcomes.