Showing papers in "Kidney International in 1993"

TL;DR: A schema for international standardization of nomenclature and criteria for the histologic diagnosis of renal allograft rejection was developed in Banff, Canada on August 2-4, 1991 and validated by the circulation of sets of slides for scoring by participant pathologists.

TL;DR: It is suggested that peritoneal dialysis, perhaps by maintaining calcium at higher levels, may more effectively suppress the parathyroid gland.

TL;DR: Vascular deposition of complement fragment C4d therefore represents a clinically relevant factor that contributes to early graft dysfunction and its assessment is helpful for an individual graft prognosis.

TL;DR: The patient was discharged to his home two months later with a BUN of 10 mg/dl and a serum creatinine of 1.1 mgldl, and the hospital course was complicated by anoxic encephalopathy, recurrent sepsis, and respiratory failure.

TL;DR: In transgenic mice bearing Epo-TAg at homologous and heterologous insertion sites, renal expression was restricted to a population of cells in the interstitium of the cortex and outer medulla, and characterization shows that these are the fibroblast-like type I interstitial cells.

TL;DR: A 24-year-old woman with chronic renal failure secondary to membranoproliferative glomerulonephritis underwent living-related renal transplantation from her 56-year old mother and received cyclosporine, prednisone, and azathioprine as immunosuppressive therapy post transplant.

TL;DR: It is concluded that hemodialysis vascular access malfunction causes much hospitalization among ESRD patients, and women, Blacks, the elderly, and diabetics appear to be at particularly high risk, and additional studies are needed to understand these patterns.

TL;DR: TGF-beta 1 is increased at the transcriptional level and thus may play a role in initiating fibrogenesis in obstructive nephropathy and the effect of thromboxane on extracellular matrix synthesis does not appear to be mediated by TGF- beta 1.

TL;DR: Data suggest that persons with nephrotic syndrome are at increased risk of CHD.

TL;DR: The predictive value of various clinical variables in assessing survival in chronic hemodialysis patients who were under treatment with hemodIALysis as of January 1991 in Okinawa, Japan and who were followed up until April 1992 was examined.

TL;DR: Intrarenal localization of cytokine producing cells and the correlation between cytokine production and histological signs of activity suggest that TNF-α and IL-1β are important locally acting mediators in the vasculitic/glomerulonephritic process.

TL;DR: The aplastic lesion is the most common form of renal osteodystrophy, with aluminum intoxication implicated in only 1/3 of the cases, and additional risk factors included treatment with peritoneal dialysis, ingestion of calcium carbonate, diabetes mellitus and advanced age.

TL;DR: The aim of this investigation was to analyze factors which influence the dietary protein intake, the energy intake and the utilization of ingested protein, and to determine the relationship between various types of nitrogen losses in stable continuous ambulatory peritoneal dialysis (CAPD) patients.

TL;DR: A 63-year-old, hypertensive, nondiabetic man with a 4-year history of gout was hospitalized because of painful swelling of his right foot, and a diagnosis of acute gouty attack was made.

TL;DR: The results showed that ETA receptor blocker reduced the abnormal permeability to proteins, limited glomerular injury and prevented renal function deterioration thus confirming the working hypothesis and suggesting that this class of compounds may eventually prove useful in the treatment of human progressive nephropathies.

TL;DR: An open, prospective, randomized, multicentric, controlled study for parallel groups, stratified for adults and children, comparing the efficacy and safety of cyclosporine with those of supportive therapy in patients with steroid-resistant idiopathic nephrotic syndrome.

TL;DR: Fasting plasma level of total, protein-bound Hcy was significantly higher in 20 patients (16 males) who had past histories of occlusive arterial disease than in the 59 (31 male) who did not (30.9 +/- 19.1 vs. 19.6 +/- 9.7 mumol/liter, P < 0.001); linear regression analysis showed a significant correlation between plasma creatinine and Hcy concentrations.

TL;DR: Examining the human peritoneal mesothelial cell (HPMC) as a possible source of this secreted IL-6 and characterize the released product and examine its regulation by other cytokines found it to be inhibited by coincubation with anti-IL-1β and/or anti-TNFα antibodies.

TL;DR: The Han:SPRD rat is the only well-documented animal model of inherited PKD with an autosomal-dominant inheritance pattern and appears to have several features which resemble human ADPKD.

TL;DR: Data indicated that plasma L-arginine was higher in uremics than in controls, uremic platelets generated more NO than control platelets, and intraplatelet levels of cGMP (the NO second messenger) were also higher in Uremic than in control platelet levels.

TL;DR: It is hypothesized that Vvmes/glom, Vvint/T, arteriolar hyalinosis, and %GS represent multiple but probably interrelated pathologic mechanisms leading to the functional disturbances of diabetic nephropathy.

TL;DR: It is suggested that NO synthesis is increased in diabetic rats manifesting hyperfiltration and is consistent with the view that excess NO synthesis contributes to renalhyperfiltration.

TL;DR: IpTH is the most helpful non-invasive investigation in this group of patients with end-stage renal failure, but single measurements of bone density are not diagnostic.

TL;DR: Parallel studies on CsA pharmacokinetics, renal function parameters (GFR and RPF), as inulin and p-aminohippurate (PAH) clearances, respectively, and urinary excretion of the vasoconstrictor endothelin in 10 consecutive renal transplant patients given Cs a as a part of their immunosuppressive therapy were performed.

TL;DR: In this article, the effects of recombinant human erythropoietin (rHuEPO) intravenously (i.v.) had higher mean arterial pressure and plasma endothelin-1 (ET-1) levels than those in which the hormone was administered subcutaneously (s.c).

TL;DR: The results confirm the importance of blood pressure control and nutritional status in chronic dialysis patients and confirm the prevalence of cerebral hemorrhage, which occurred at 10 years younger than that of the general population and was associated with high prevalence of hypertension and low levels of serum albumin and cholesterol.

TL;DR: The effects of interruption of the renin-angiotensin system in rats that were volume depleted by water deprivation for 48 hours (AWD) with/without furosemide were studied to examine effects of a specific bradykinin antagonist (Hoe).

TL;DR: The association of severely and medium deficient PI phenotypes with anti-PR3 positive systemic vasculitis, and postulate a pathogenetic role for alpha 1-AT deficiency and the occurrence of ANCA are described.