Showing papers in "Kidney International in 1998"

TL;DR: The purpose of this perspective is to understand the results of the recent, largely negative, clinical trials in view of recent advances in the epidemiology of ARF.

TL;DR: The value of the IIF test for ANCA detection can be greatly increased by the addition of a well standardized antigen-specific ELISA, and the diagnostic specificity increased to 99%.

TL;DR: In this article, a Cox regression was used to assess the effect of systolic and diastolic blood pressure (SBP) on the risk of cardiovascular and cerebrovascular morbidity in hemodialysis patients.

TL;DR: It is concluded that post-transplant blood pressure is a highly significant predictor of long-term kidney graft outcome and whether aggressive lowering of blood pressure improves long- term transplant outcome will have to be studied prospectively.

TL;DR: The stereotyped development of the glomerular lesions in many animal models and human forms of progressive renal disease suggests that there are common mechanisms of disease progression, and this work proposes the outline of such a mechanism based on following aspects.

TL;DR: The serum albumin (SAlb) level was not only a predictor of nutritional status, but was independently influenced by age, sex and SCRP, and plasma amino acid levels, with the possible exception of the branched-chain amino acids, seem to be poor predictors of nutritional Status in hemodialysis patients.

TL;DR: The results indicate that CTGF may be a common growth factor involved in renal fibrosis, and an increase in the number of cells expressing CTGF mRNA was observed at sites of chronic tubulointerstitial damage, which correlated with the degree of damage.

TL;DR: Higher levels of circulating proinflammatory cytokines areassociated with mortality, while immune parameters reflecting improved T-cell function are associated with survival in ESRD patients treated with HD, independent of other medical risk factors.

TL;DR: It is postulate that abnormalities of factor H may be involved in the etiology of HUS.

TL;DR: The data of the prospective epidemiological ARF study carried out in Madrid is reviewed using two different approaches: comparing the ARF cases observed in the ICU setting with those ARF studied outside theICU, and comparing the outcome of isolated ARF with the outcomes of ARF as part of a MODS in patients treated in both settings.

TL;DR: Peripheral vasodilation occurs early in pregnancy prior to full placentation in association with renal vasodilated and activation of the renin-angiotensin-aldosterone system, suggesting that ANP increases in response to changes in intravasular volume.

TL;DR: In chronic nephropathies proteinuria is the best independent predictor of both disease progression and ESRF, and mean UProt and mean arterial pressure and systolic blood pressure during follow-up were the only time-dependent covariates that significantly correlated with delta GFR.

TL;DR: Given its chemotactic activity, RANTES released into the interstitium might promote inflammatory cell recruitment and contribute to interstitial inflammation and renal disease progression.

TL;DR: P phenotypic and morphological evidence is provided to support the hypothesis that TEC are pro-fibrogenitor cells capable of tubular epithelial-myofibroblast transdifferentiation in progressive renal fibrosis.

TL;DR: Lower levels of social support, decreased behavioral compliance with the dialysis prescription, and increased negative perception of the effects of illness are independently associated with increased mortality in ESRD patients treated with HD.

TL;DR: Increased adhesion following chronic shear stress has been exploited to generate vascular grafts with confluent EC monolayers, retained after implantation in vivo, thus overcoming a major obstacle to endothelialization of vascular prostheses.

TL;DR: A logistic regression analysis performed using the laboratory variables revealed a strong, independent, and inverse relationships between the serum albumin and creatinine concentrations, total lymphocyte count, and the odds risk of death.

TL;DR: Several studies of long-term PD in the literature now complement each other in providing a picture of what really happens to PD patients, and strategies that maintain nutrition and preserve peritoneal membrane function must be developed.

TL;DR: NHD is more effective in controlling serum phosphate levels than CHD, allowing patients to discontinue their phosphate binders completely and to ingest a more liberal diet.

TL;DR: The present data document that insulin resistance and concomitant hyperinsulinemia are present early in the course of renal disease, that is, even in patients with GFR within the normal range, irrespective of the type of kidney disease.

TL;DR: In patients with ARAS, there is a significant risk of renal atrophy among kidneys exposed to elevated systolic blood pressure and among those with high-grade ARAS and low renal cortical blood flow velocity as assessed by renal duplex scanning.

TL;DR: It is concluded that HCV infection at the time of referral for transplantation is associated with an increased risk of death, irrespective of whether patients remain on dialysis or undergo transplantation.

TL;DR: Smoking increases the risk of ESRF in men with inflammatory and non-inflammatory renal disease in a retrospective multicenter case-control study including 582 patients from Germany, Italy and Austria.

TL;DR: Increased time ondialysis prior to renal transplantation is associated with decreased survival of transplant recipients, and increasing time on dialysis increases the prevalence of both left ventricular hypertrophy and cardiomegaly.

TL;DR: The data strongly support a critical role for iron in mediating tissue injury via hydroxyl radical (or a similar oxidant) in this model of nephrotoxicity.

TL;DR: The current studies demonstrate a previously unrecognized link between Ang II and MC O2- production that may participate in the pathophysiology of progressive renal disease by concomitantly affecting the hemodynamics of the glomerular microcirculation as well as growth related responses of MC to injury.

TL;DR: The data support the concept that the combination of an ACE inhibitor with a non-DHPCA reduce proteinuria to a greater extent than either agent alone and could have ramifications for slowing renal disease progression in patients with nephropathy from type 2 diabetes.

TL;DR: A program for early placement of A-V fistulae, a continuous quality improvement, multidisciplinary program to monitor access outcome, the development of new biomaterials, and a research plan to investigate pharmacological intervention to reduce development of stenosis and clinical interventions to treat those that do develop, prior to thrombosis are proposed.

TL;DR: The patient had recurrent episodes of arthralgia, purpura, and abdominal colic over 2 years, and his blood pressure was markedly elevated, and severe retinal lesions (grade 3 hypertensive retinopathy) were present.