Showing papers in "Microvascular Research in 1982"
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TL;DR: This method of quantitation of protein leakage in the microcirculation of the rat cremaster muscle gave reproducible data that can be used to determine the time course ofprotein leakage and to compare concentration-dependent phenomena.
101 citations
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TL;DR: Extensive structural similarities between microvessels of the frog mesentery and those of mammalian skeletal muscles were demonstrated, indicating that frog mesenteric capillaries are a useful model of mammalian continuous capillary in general.
87 citations
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TL;DR: It is concluded that insonation of skeletal muscle transiently constricts the small arterioles, but that long-term treatment can improve perfusion in vascularly impaired muscle.
74 citations
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TL;DR: Fuid flux was significantly increased in the lung for 24–36 hr, but protein sieving was normal as demonstrated by a decrease in L P ratio for all protein fractions, indicating the increase in ( L ) to be due to an increase in microvascular hydrostatic pressure.
68 citations
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TL;DR: The number of perfused capillaries at rest and during contractions was estimated in rat extensor digitorum muscle by staining for erythrocytes and expressed as a capillary/muscle fiber ratio (C/F) either in muscles taken quickly out of the animal and fixed in glutaraldehyde, or in muscle frozen in situ.
68 citations
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TL;DR: It is shown that asymmetric cell shapes lead to tank-treading motion of the membrane, and also to a reduction in the driving pressure required to sustain a given cell velocity.
67 citations
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TL;DR: In order to provide a firm basis for the analysis of experiments on the kinetics of ion and solute exchange in bone, the total water space, extracellular space, and vascular space in the tibial diaphysis in adult dogs were estimated.
65 citations
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TL;DR: Results may indicate that administration of PEG-SOD may be an adequate approach for preventing the occurrence of O .
65 citations
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TL;DR: The closest-individual method is potentially of great use to studies of capillarity since it calculates median diffusion distance more accurately than estimates from capillary density alone; it calculates maximal diffusion distance, which cannot be estimated from capillaries density alone.
57 citations
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TL;DR: Over 99% of the developed smooth muscle force is transmitted circumferentially in hamster pouch arterioles, and the manner in which structural parameters affect arteriolar mechanical properties is discussed.
53 citations
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TL;DR: The overall shape of pericytes on the surface of small blood vessels in a rat red muscle, as seen by scanning electron microscopy, suggests that pericytic processes are contractile and that they play a role in microvascular control.
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TL;DR: Fluorescent blood platelets flowing in a microvessel can be localized objectively within a finite and thin optical section, allowing the investigation of their rheological behavior in vivo.
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TL;DR: A method for the measurement of the hematocrit of blood flowing in small-bore glass tubes (HT) is examined which relies upon a linear relationship between the difference in optical densities (ΔOD) at two isobestic wavelengths for oxy- and deoxyhemoglobin and the product of HT and luminal diameter (DT).
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TL;DR: It is concluded that the early increase in perfusion probably reflects the development of a blood supply which is not under the usual constraints and control and probably reflects local mechanical factors which may account for some of the reported differences in tumor growth in various locations.
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TL;DR: Variations of PS in parallel with CBF are evidence of capillary recruitment which constitutes a more efficient way of increasing tissue supply, indicating that autoregulatory mechanisms do not affect the diffusional exchange surface and probably take place at the arteriolar level.
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TL;DR: The results suggest that the adrenergic and cholinergic nerve fibers are distributed in the smooth muscle layers as well as in the adventitia of bovine mesenteric lymphatics.
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TL;DR: The hamster retractor muscle is a long strap-shaped muscle which has its origin on the spinal processes of the last three thoracic vertebrae and inserts proximal to the blind end of the cheek pouch and makes it an attractive vascular bed for mathematical modeling of microcirculatory mass transport experiments.
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TL;DR: Although replicating endothelial cells were not observed in the angiotensin II-treated vessels, endothelial cell replication was found in controls where the vessels were mechanically injured.
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TL;DR: It is concluded that the three methods give the same π i in the same area of human subcutaneous tissue provided equal implantation time and little or no suction in empty wick catheters.
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TL;DR: It is concluded that inflammatory stimuli which lead to alterations in microvessels depend on a facilitatory effect of insulin, and endogenous insulin and glucocorticoids act as modulators of inflammatory responses.
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TL;DR: It is demonstrated that neither endogenous prostanoids nor endogenous histamine are responsible for vascular escape from adrenergic vasoconstriction, and prostaglandin E 2 produced dose-related dilatation of gastric submucosal arterioles.
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TL;DR: Arcade arterioles of cat mesentery were fixed in vivo at normal and elevated intravascular pressures and studied by transmission electron microscopy, revealing a smooth, cylindrical appearance while the intima, media, and adventitia were quite irregular in cross section and longitudinal section.
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TL;DR: A model has been developed to establish the determinants of glomerular function by means of a network analysis and the efferent ultrafiltration pressure was close to the value predicted from the micropuncture data.
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TL;DR: The results demonstrate that whole-organ and single-capillary techniques for studying muscle capillary permeability yield values which comply within a factor of about 2.5, being 5–10 times less permeable to potassium ions although both belong to the category of continuous capillaries.
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TL;DR: It is proposed that relaxation of bradykinin-contracted endothelial cells is a mechanism of microvascular wall repair consistent with those leakage sites which repeatedly respond to brady Kinin stimulation, and platelet plugging of interendothelial gaps may have occurred in those leakage Sites refractory to subsequent applications of br Bradykinin.
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TL;DR: A maximal P if of +5 mm Hg was observed in edematous legs indicating a high compliance of the subcutaneous tissue in patients with postreconstructive leg edema.
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TL;DR: The aggregation of platelets in injured cerebral arterioles was delayed as the wall shear rate rose, over a range of 0.2 to 1.4 sec−1.4 seconds, and the correlation between aggregation latency andShear rate was 0.44, P.
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TL;DR: The concentric-circles method generated estimates of median and maximal distances to the nearest capillary, and provided complete distributions of distances that were statistically similar to predictions, and deviated from predictions by an average of less than 10%.
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TL;DR: The reflection coefficients (σ) and permeability surface area products (PS) were estimated for total plasma proteins in dog-paw lymph in this article, and the results showed that at low lymph flow states convection provides for 70% of the protein transport and diffusion only 30%.
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TL;DR: A new optical system based on the projection of the erythrocyte image onto two photodiodes through a prism grating is extensively applied for the first time and is compared to the two-slit methods, the laser-Doppler-anemometry and high-speed cinematography.