Showing papers in "Neurologic Clinics in 1989"

TL;DR: Myofascial pain syndrome is a regional muscle pain disorder that is the most common physical diagnosis causing chronic pain and management programs involving rehabilitating the affected muscles and controlling the contributing factors are effective if long-term compliance is maintained by the patient.

TL;DR: It is critically important to educate patients about the process of amputation and the physiologic mechanisms of phantom sensation and pain in order to minimize magnification of pain due to stress.

TL;DR: Using new DNA probes, highly accurate genetic counseling can be provided for families with DM and isolation of the DM gene is expected in the near future and may allow planning of effective therapies.

TL;DR: A comprehensive approach to diagnosis of patients with lissencephaly using clinical, CT and MRI scan, and sometimes other laboratory data will allow a specific diagnosis to be made in a large majority of patients.

TL;DR: The schema in Table 1 illustrates the inter-relationship between the major fluid and electrolyte disturbances with their primary site of involvement, that is, the CNS or peripheral nervous system (PNS), their primary effect (nervous system depression or irritability), and the major symptom complex associated with these sites and mechanisms (obtundation, seizures, muscle weakness, and tetany).

TL;DR: Early prognostication can still serve other useful purposes, however, including the counseling of families, triage and DNR decisions, and future clinical investigations of brain-resuscitative measures.

TL;DR: The signs and symptoms, natural history, and diagnosis of trigeminal neuralgia are reviewed, and current views on its pathogenesis and on available medical and surgical treatment modalities are discussed.

TL;DR: As the population of HIV infected individuals continues to grow, the incidence of coincidental non-HIV neurologic disease will also rise, and attention must be directed to identifying coexistent remediable causes of neurologic dysfunction in this population.

TL;DR: Elucidating the details of the changes of neural function associated with chronic pain would help more intelligently to develop treatments to reverse these pathologic changes and thus treat chronic pain more effectively.

TL;DR: Understanding of the mechanisms that underlie neuropathic pain is poor, although there is evidence for widespread changes within the peripheral and central somatosensory nervous systems of such patients.

TL;DR: This article reviews the changing perspectives on migraine and other chronic headache syndromes and addresses the current interest in "central" (brain) pathogenetic mechanisms and various aspects of the diagnostic evaluation, classification, and treatment.

TL;DR: Therapeutic strategies include reduction of dietary cholesterol, apheresis techniques designed to reduce LDL cholesterol available to cells, and reduction of formation of LDL and increase of synthesis of HDL to lower cellular uptake of cholesterol and enhance egress of this lipid from intracellular storage sites.

TL;DR: Renal failure and its treatment are associated with a number of neurologic complications that must be differentiated from the nervous system complications of the disease leading to renal failure, including uremic encephalopathy and peripheral neuropathy.

TL;DR: Chronic intractable pain syndrome can markedly debilitate the patient and needs an aggressive approach with drug therapy as the first-line approach.

TL;DR: It is believed strongly that it is time to lay aside the moral, legal, and ethical conflicts that have needlessly delayed or prevented physicians from complying with the resolute decisions that competent patients have made about their own lives.

TL;DR: Presentations associated with acute systemic sarcoidosis and cranial nerve lesions tend to have a better prognosis, with frequent spontaneous resolution and good response to corticosteroids.

TL;DR: A classification of pain pathophysiology is proposed in an effort to clarify the relationship between clinical phenomena and the diverse findings of studies performed in animal and human models of experimental pain.

TL;DR: The proposed pathophysiology of the various symptoms and signs of glycogen metabolism in muscle will be presented and the many unsolved problems in this area will be discussed.

TL;DR: In this paper, the role and functions of a "neuroethicist" are discussed and common clinical examples that illustrate how a neurologist can be of value in these neuroethical dilemmas in the clinical setting.

TL;DR: People with Prader-Willi syndrome exhibit infantile hypotonia and failure to thrive, genital hypoplasia, childhood-onset obesity, mental deficiency and behavioral abnormalities, hypogonadism, short stature, and characteristic dysmorphology.

TL;DR: Treatment involves a variety of pharmacologic and nonpharmacologic approaches, but therapy must be individualized for each specific pain syndrome according to its own pathophysiology.

TL;DR: New therapeutic and surgical alternatives to the treatment of Wilson disease also enhance the therapeutic options and the fate of patients with Wilson disease with fulminant hepatic disease and those patients unable to tolerate or unresponsive to penicillamine therapy has been greatly improved.

TL;DR: The authors illustrate the application of ethical principles in neurologists' management of patients in persistent vegetative states, dementia, and end-stage neuromuscular disease.

TL;DR: The vasculitides are a heterogeneous group of disorders that cause blood vessel inflammation and necrosis and a systematic diagnostic and therapeutic approach is crucial in these patients, as immunosuppressive therapy is effective in many of these disorders.

TL;DR: The findings seen in disorders of calcium metabolism, thyroid and adrenal disease, diabetes mellitus, and acromegaly are reviewed.

TL;DR: The sleep apnea syndromes are a group of disorders in which abnormal respiratory patterns during sleep result in hypercapnia and hypoxemia, and treatment includes restoring adequate ventilation and improving gas exchange and may require tracheal intubation and assisted ventilation.

TL;DR: The authors outline the clinical course of a demented patient in order to examine how different ethical issues tend to arise in different stages of dementia.

TL;DR: The Charcot-Marie-Tooth syndrome is not a single disease but has a multitude of genetic causes and conditions produced by mutations on the X chromosome such as X-linked HMSN, Fabry trihexoside storage disease, and adrenomyeloneuropathy.

TL;DR: Patients presenting with one of the more distinctive syndromes, such as subacute cerebellar degeneration, opsoclonus-myoclonuses, and the Lambert-Eaton syndrome, should undergo a careful evaluation for the presence of an occult malignancy.

TL;DR: Recognition of the potential neurologic consequences of prolonged deficiency states also is important for the internist, because many of the syndromes are poorly reversible once symptomatic and the benefits of prevention invariably exceed those of treatment.