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Showing papers in "Progress in Cardiovascular Diseases in 1989"


Journal ArticleDOI
TL;DR: Etude de mecanisme d'action de l'adenosine sur differentes cellules cardiaques and examen de son metabolisme, discussion du role possible of l' adenosine comme mediateur des fonctions cellulaires cardiaque.

770 citations


Journal ArticleDOI
TL;DR: In patients with stable angina, a prolonged increase in glucose uptake could be demonstrated in the post-ischemic myocardium in the absence of perfusion abnormalities, and a state of chronic metabolic ischemia is proposed.

272 citations





Journal ArticleDOI
TL;DR: Amiodarone can have a tremendous beneficial effect in the proper circumstances, but it is a drug that should command utmost respect because of its side effects and requires constant vigilance from any physician wishing to use it.

112 citations


Journal ArticleDOI
TL;DR: It is believed that carotid sinus hypersensitivity is still a relatively overlooked cause of syncope, partly related to the difficulty of establishing a clear-cut cause and effect relationship between CSH demonstrated at bedside or in the laboratory, and the patient’s previous syncopal attacks.

102 citations


Journal ArticleDOI
TL;DR: The present study evaluates the autopsy experience and findings at UCLA Medical Center with attention focused on cardiac lesions in AIDS patients, including fibrinous pericarditis and Kaposi’s sarcoma which involved the heart.

102 citations


Journal ArticleDOI
TL;DR: An appreciation of the mechanism of the interaction between amiodarone and thyroid hormone metabolism allows the clinician to recognize thyroid dysfunction at an early stage and initiate appropriate therapy, thereby minimizing the morbidity associated with forms of amioarone toxicity.

79 citations


Journal ArticleDOI
TL;DR: The experimental findings described suggest some potential new directions forAntianginal therapy and, along with recent clinical observations, support the use of combinations of antianginal agents that act by different mechanisms.

57 citations


Journal ArticleDOI
TL;DR: The intention of this review is to summarize the methodology and principles of signal averaged electrocardiography and to analyze critically many of the published reports to better define its current status.

Journal ArticleDOI
TL;DR: Its toxicity should temper enthusiasm for the use of the medication in non-life-threatening arrhythmias, but the advent of improved surgical techniques and the relatively low risk of an operation make surgery the treatment of choice.

Journal ArticleDOI
TL;DR: IV amiodarone may be poten- tially useful in the therapy of patients with frequent or incessant arrhythmias, and there may be patients with severe systemic ill- nesses in whom IV therapy may be the only method available for delivering an antiarrhythmic agent.

Journal ArticleDOI
TL;DR: A hypertensive urgency should be distinguished from a hypertensive emergency in order to select the therapeutic approaches that are most appropriate for each patient.

Journal ArticleDOI
TL;DR: In this article, it is shown that patients with multiple recurrences of sustained ventricular tachycardia (VT) may be more hemodynamically stable during their arrhythmia and less prone to sudden cardiac death than other patient populations with ventricular arrhythmias.

Journal ArticleDOI
TL;DR: Therapeutic transcatheter procedures have been developed that can provide palliative or definitive therapy to children with a variety of congenital cardiovascular disorders and some procedures have become the treatment of choice while others remain investigational.

Journal ArticleDOI
TL;DR: Key features that should be used in defining this entity in future studies include: (1) biopsy evidence of alveolitis, (2) diffuse pulmonary infiltrates or infiltrates involving the upper lung zones, (?) dyspnea and cough, and (5) improvement after stopping or decreasing the dose of amiodarone.

Journal ArticleDOI
TL;DR: Until more convincing evidence against coffee is compiled, it appears that, at least in moderate amounts in otherwise healthy persons, coffee is a safe beverage.

Journal ArticleDOI
TL;DR: Antiarrhythmic drugs may increase the minimum energy required for defibrillation, thus rendering implantable cardioverter defibrillators or external DC cardioversion less effective, and the drug-related potentiation of symptomatic arrhythmia by the production of a hemodynamic poorly tolerated tachycardia.

Journal ArticleDOI
TL;DR: This article details an approach to common angioplasty questions, problems, and attempted solutions.