Showing papers in "The American Journal of the Medical Sciences in 2000"
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TL;DR: In this article, the American Heart Association reported that respiratory sinus arrhythmia foreshadows doxorubicin, a drug that is used to prevent doxoring.
456 citations
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TL;DR: A simple approach grounded in the physiology of electrolyte-free water clearance that can be used at the bedside for the management of hypotonic hyponatremia is described.
135 citations
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TL;DR: Delayed orthostatic hypotension and/or tachycardia caused by excessive gravitational venous pooling, which is correctable with external lower-body compression, together with subnormal circulating erythrocyte volume, are very frequent, although not invariably demonstrable, findings in moderate to severe chronic fatigue syndrome.
134 citations
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TL;DR: A wealth of studies performed with a spectrum of methods spanning simple clearance studies to the molecular identification of ion transporters has increased the understanding of how approximately 1.7 kg of NaCl and 180 L of H2O are absorbed by renal tubules in man and how the urinary excretion is fine-tuned to meet homeostatic requirements.
129 citations
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TL;DR: Drugs and alcohol are the most common causes of macrocytosis in hospitalized patients in a New York City teaching hospital, and tentative guidelines for the evaluation of high MCV values are formulated.
119 citations
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TL;DR: In this paper, the authors describe the localization of a stable form of C-reactive protein (CRP) in blood vessels associated with normal human tissues, termed modified CRP or mCRP, which is a tissue-based rather than serum-based molecule.
116 citations
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TL;DR: Using pharmacokinetics and pharmacodynamics of diuretics, the authors can design therapeutic regimens in which satisfactory control of fluid and electrolyte homeostasis can be achieved in the vast majority of patients.
103 citations
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96 citations
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TL;DR: A resistance-training program may be included safely in a multidisciplinary weight management program for obese preadolescent male and female children and may improve program retention especially in severely obese youth.
95 citations
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TL;DR: Data indicate that urinary podocytes may be markers of the severity of lupus nephritis and that steroid therapy may be effective for podocyte injury in lupu nephitis.
91 citations
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TL;DR: A vigorous and growing scholarship and body of experience is propelling the field of literature and medicine to understand all the more clearly how acts of reading and acts of writing might illuminate acts of doctoring.
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TL;DR: The physician should define moderate drinking for the patient and should review consumption patterns associated with high risk and there is no evidence to support endorsement of one type of alcoholic beverage over another.
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TL;DR: The following review summarizes the present knowledge of the role of EDCF and EDRF in such processes with major focus on pulmonary endothelial dysfunction in hypoxia-induced pulmonary hypertension.
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TL;DR: Tuberculous sternal osteomyelitis should be considered in patients with sternal pain and swelling, and based on histologic examination of infected tissues and mycobacterial cultures, in patients in which tuberculosis is endemic.
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TL;DR: A case of hypoplasia of the inferior vena cava with azygous continuation in a 30-year-old man who presented with recurrent deep venous thrombosis is reported.
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TL;DR: The metabolism of glucose through the HBP mediates extracellular matrix production, possibly via the stimulation of TGF-beta in kidney cells, and may play a role in the development of diabetic nephropathy.
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TL;DR: Patients with adynamic bone (with or without aluminum) would have more difficulties in handling and buffering calcium loads; consequently, they would have a higher risk of extraosseous calcifications.
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TL;DR: The ominous prognosis ascribed to generalized BMn seems to reflect the poor outcome of such underlying conditions as leukemia; however, the prognosis of generalized BMN is not so poor in association with SCD and other nonmalignant states.
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TL;DR: Hematitis C virus infection may be more prevalent among hospitalized VA patients (and among other US hospital populations) than previously expected.
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TL;DR: Anginal chest pain may be a marker for myocardial ischemia and, in the presence of abnormal ventricular repolarization, may cause lethal ventricular arrhythmias and sudden death in persons exposed to cocaine.
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TL;DR: A spectrum of EBV- associated diseases in patients with immunodeficiency are summarized and discussed mainly focusing on their pathogenetic mechanism(s).
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TL;DR: Additional research is needed to further elucidate the pathophysiology of RLS, through obtaining post-mortem specimens and refinement of neuroimaging and neurophysiologic techniques, to result in better understanding of this disease at the molecular level.
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TL;DR: It is suggested that 15 to 20% of adults who are long-term survivors of acute leukemia develop iron overload, often with hepatic abnormalities, and routine evaluation should be performed and therapeutic phlebotomy should be used as treatment.
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TL;DR: In the nervous system, ion channels and neurotransmitter receptors that function as ligand-gated ion channels seem to be favored targets for autoantibody attack, and neuromyotonia can now be added to the growing list of autoimmune channelopathies.
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TL;DR: In this paper, the authors present a review of the current understanding of how approximately 1.7 kg of NaCI and 180 L of H2O are absorbed by renal tubules in man and how the urinary excretion is fine-tuned to meet homeostatic requirements.
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TL;DR: Evaluating the reliability and features of concurrent validity of 4 dyspnea scales in illiterate (IL) subjects with COPD showed comparable reliability in both L and IL COPD subjects.
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TL;DR: It is reported that 5 cases of CD are treated in the institute and the literature about the management of this relatively rare disorder is reviewed, with mixed results.
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TL;DR: The aim of this study was to determine whether chronic FR promotes more significant changes in myocardial performance in patients subjected to cardiac overload.
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TL;DR: This work outlines the current approach to teaching medical ethics and believes successful medical ethics teaching requires medical schools to commit significant material and moral support.
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TL;DR: Avoiding the use of drugs that are cytochrome P450 3A4 and/or P-glycoprotein substrates reduces the risk of rhabdomyolysis caused by 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors.