Journal ArticleDOI
85-P Near normal ImmuKnow responses in HLA identical renal transplant recipients given donor hematopoetic stem cells and alemtuzumab despite profound T cell depletion
James M. Mathew,Joseph R. Leventhal,John J. Friedewald,Josh Levitsky,Jane Charette,Li Chen,Dhivya Chandrasekaran,Anat R. Tambur,Joshua Miller +8 more
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This article is published in Human Immunology.The article was published on 2011-10-01. It has received 1 citations till now. The article focuses on the topics: Alemtuzumab & Stem cell.read more
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Requirement of Cognate CD4+ T-Cell Recognition for the Regulation of Allospecific CTL by Human CD4+CD127−CD25+FOXP3+ Cells Generated in MLR
Yuming Yu,Yuming Yu,Joshua Miller,Joshua Miller,Joseph R. Leventhal,Anat R. Tambur,Dhivya Chandrasekaran,Josh Levitsky,Xunrong Luo,James M. Mathew,James M. Mathew +10 more
TL;DR: It was concluded that human CD4+CD127−CD25+FOXP3+ MLR-Tregs down-regulate alloreactive cytotoxic responses, and CD8+ CTL regulatory mechanisms include impaired proliferation, reduced expression of cytolytic molecules and CD25+ activation epitopes.